Journal of Cancer Research and Therapeutics
Papers 3,772
1 page of 378 pages (3,772 results)
#1Syed Lidia Hossain (Sir M. Visvesvaraya Institute of Technology)
#2Manoj Mathews (St. Joseph's College, Bangalore)H-Index: 15
Last. C. Rajendra Singh (Sir M. Visvesvaraya Institute of Technology)H-Index: 3
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Objective null To evaluate the antiproliferative and apoptosis inducing activity of different sydnones on cancer cell lines and their interaction with cancer proteins by molecular docking studies. null Material and methods null Antiproliferative activity was carried out by MTT assay and apoptosis inducing activity was performed by DAPI and Annexin V and propidium iodide staining. Molecular docking studies were performed using AutoDock Tools 1.5.6. Pharmacokinetics properties like ADME and toxici...
Objective The purpose of this study is to analyze predisposing factors for a higher risk of recurrence in esophageal cancer patient who underwent surgery for curative intent and to do survival analysis of prognostic factors. Materials and Methods Between February 2018 and March 2020, we retrospectively identified 28 cases staged T1b to T4a managed electively at our institute as per multidisciplinary management plan. Demographic, clinical, radiological, operative, histopathological parameters, up...
#1Cui-min Zhu (Chengde Medical College)H-Index: 1
#2Xiang-yao Lian (Chengde Medical College)H-Index: 1
Last. Qing-shan Li (Chengde Medical College)H-Index: 1
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Objective The objective of this study was to perform a meta-analysis comparing the efficiency of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) with chemotherapy to EGFR TKI treatment alone in patients with EGFR mutation-positive non-small cell lung cancer (NSCLC). Materials and Methods Following keyword queries in databases and identification of randomized control trials for inclusion, hazard ratios (HRs), relative risks (RRs), and associated 95% confidence intervals ...
Purpose The replication protein A3 (RPA3) is a subunit of the RPA protein complex, which plays an essential role in multiple processes of DNA metabolism. However, the involvement of RPA3 bladder urothelial carcinoma (UC) prognosis has not yet been elucidated. The aim of our study is to investigate the prognostic role of RPA3 expression in patients with bladder UC. Materials and Methods Bladder UC tissue specimens from 155 consecutively treated patients who underwent surgery between 2013 and 2018...
#1Yunfang Li (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)
#2Yuan-Ming Li (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 3
Last. Xiaoguang Li (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 7
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Purpose: The purpose was to evaluate the effect of thermal ablation combined with activated functional killer (AFK) cells immunotherapy for patients with malignant tumors. Materials and Methods: A cohort of 10 patients with malignancies received thermal ablation combined with AFK cells immunotherapy. Progression-free survival (PFS), overall survival, laboratory test, and postoperative complications were assessed. Results: The success rate of the combination therapy was 100% and no severe complic...
Objectives The aim of the study was to compare the relative diagnostic utility of low-dose computed tomography (LDCT) and standard-dose computed tomography (SDCT)-guided lung biopsy approaches. Materials and Methods The PubMed, Embase, and Cochrane Library databases were searched for relevant studies published through August 2020. Data pertaining to endpoints including technical success, diagnostic performance, operative time, radiation dose, and complications, were extracted, and meta-analysis ...
#1Yang LiangH-Index: 1
#2Chuang LiH-Index: 4
Last. Ruoyu WangH-Index: 9
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Aims This study aimed to investigate the clinical value of 125I radioactive particle implantation combined with regional arterial chemotherapy perfusion in the treatment of pancreatic cancer. Subjects and Methods The clinical data of 23 patients with pancreatic cancer were retrospectively analyzed, and the patients were divided into two groups. In the observation group, 11 patients were injected with radioactive particles in combination with regional arterial chemotherapy. In the control group, ...
#1Xujian Han (SDU: Shandong University)
Last. Ximing Wang (SDU: Shandong University)
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Objectives The aim of this study was to evaluate the feasibility, accuracy, and safety of computed tomographic (CT)-guided coil localization before video-assisted thoracoscopic surgery. Methods One hundred and eighty-four consecutive patients with 200 pulmonary nodules who underwent CT-guided percutaneous coil localization before thoracoscopic surgery were retrospectively analyzed in this study. Success rate for localization, complication rates, CT findings, and pathological results of the lesio...
#1Baodong Gai (Jilin University)H-Index: 2
#2Qingchun Li (Jilin University)H-Index: 5
Last. Dongyan Yang (Jilin University)H-Index: 1
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Objective The objective of the study was to identify the advantages of interstitial radioactive seed implantation for the treatment of Stage III pancreatic cancer. Materials and Methods Clinical data of 160 patients with pancreatic cancer implanted with radioactive seeds were retrospectively analyzed. Patients were grouped according to tumor size, lymph node metastasis, and tumor invasion to important blood vessels, and survival time statistics were obtained. Results The mean postoperative survi...
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