International Journal of Antimicrobial Agents
Papers 9805
1 page of 981 pages (9,805 results)
#2Tanguy Déméautis (UCBL: Claude Bernard University Lyon 1)
Last. Gilles Devouassoux (UCBL: Claude Bernard University Lyon 1)H-Index: 24
view all 16 authors...
ABSTRACT null null Aspergillus fumigatus resistance to triazoles is increasingly reported in Europe. As few data are available in Southern France, our objectives were to assess the burden of A. fumigatus isolates with azole resistance from clinical specimens in Lyon and explore the involved resistance mechanisms. In this retrospective cross-sectional study, 221 consecutive A. fumigatus isolates from respiratory samples were identified during an eight-month period from 195 patients attending the ...
1 CitationsSource
#1Piergiorgio CojuttiH-Index: 15
#2Matteo Rinaldi (UNIBO: University of Bologna)H-Index: 31
Last. Federico Pea (UNIBO: University of Bologna)H-Index: 37
view all 6 authors...
Abstract null null Dalbavancin is increasingly used for the treatment of staphylococcal osteoarticular infections. Some population pharmacokinetic studies suggest that a two 1500 mg dosing regimen one-week apart could ensure effective treatment for several weeks. Here we want to provide clinicians with a proof-of-concept of the potential role that therapeutic drug monitoring (TDM) may have in giving a real-time feedback of the estimated duration of optimal treatment of staphylococcal osteoarticu...
#1Yuki Yoshikawa (Harvard University)
#2Isabelle Feldhaus (OECD: Organisation for Economic Co-operation and Development)
Last. Michele Cecchini (OECD: Organisation for Economic Co-operation and Development)H-Index: 17
view all 5 authors...
Abstract null null Improving prudent use of antibiotics is one way to limit the spread of antimicrobial resistance (AMR). The objective of this systematic review was to assess the effects of financial strategies targeting healthcare providers on the prudent use of antibiotics. null A systematic review of the literature was conducted searching PubMed, Embase and Cochrane databases, and the grey literature. Search terms related to antibacterial agents, drug resistance, financial strategies, and he...
#1Chidozie Declan Iwu (University of Pretoria)H-Index: 6
#2Sean Mark Patrick (University of Pretoria)H-Index: 6
Abstract null null Introduction null The Global Action Plan (GAP) on antimicrobial resistance (AMR) delivers a ‘One Health’ strategy for the development of the national action plan. It encourages the optimal use of antimicrobials and strengthens the evidence base through surveillance and research. null null null Methods null This study evaluated the current status of implementation of the GAP on AMR in World Health Organization (WHO) African countries via a retrospective, cross-sectional analysi...
#1Harald Seifert (University of Cologne)H-Index: 76
#2Marie-Louise von Linstow (Copenhagen University Hospital)H-Index: 12
Last. Michael J. Dowzicky (Pfizer)H-Index: 26
view all 4 authors...
Abstract null null Aims null Data on antimicrobial resistance (AMR) in the pediatric patient population are scarce. Here, we assess the AMR rates and phenotype distribution of Gram-negative isolates in pediatric patients in Europe from 2004-2012 and 2013-2018. null null null Methods null Isolates collected were stratified by age groups ( null null null Results null In the overall pediatric patient population (0-17 years), extended-spectrum beta-lactamase (ESBL) production significantly decreased...
Abstract null null We investigated the prevalence, resistance mechanisms and activity of ceftazidime/avibactam, meropenem/vaborbactam, imipenem/relebactam and comparator agents against carbapenem-resistant Enterobacterales (CRE) that did not carry carbapenemase genes. Among 304 CRE isolates collected in US hospitals during 2016–2018 (1.1% of the overall Enterobacterales), 45 (14.8%) isolates did not carry carbapenemases. These isolates were mainly Klebsiella aerogenes (n = 11), Enterobacter cloa...
#1Cindy Lau (USYD: University of Sydney)H-Index: 2
#2Deborah Marriott (UNSW: University of New South Wales)H-Index: 61
Last. Stephanie E. Reuter (UniSA: University of South Australia)H-Index: 12
view all 9 authors...
Abstract null null Background null Cefepime-induced neurotoxicity (CIN) is an increasingly reported adverse event; however, the toxicity threshold remains unclear. This study was conducted to provide a comprehensive examination of the most appropriate threshold for CIN, and evaluate the ability of current dosing regimens to attain therapeutic targets. null null null Methods null Data of CIN incidence and cefepime plasma concentrations were collected retrospectively from patients administered cef...
#1Joseph Meletiadis (UoA: National and Kapodistrian University of Athens)H-Index: 40
#2Paschalis Paranos (UoA: National and Kapodistrian University of Athens)
Last. Spyros Pournaras (UoA: National and Kapodistrian University of Athens)H-Index: 53
view all 8 authors...
Abstract null null Metallo-beta-lactamase (MBL)-producing Gram-negative bacteria are increasing worldwide and very few agents are active against these pathogens. Taniborbactam (formerly VNRX-5133) is a newly developed bicyclic boronate beta-lactamase inhibitor that directly inhibits all four Ambler classes of beta-lactamases. In the present study the in vitro activity of cefepime or meropenem combined with taniborbactam against 100 Klebsiella pneumoniae and cefepime combined with taniborbactam a...
#1Jesus Magallon (CSUF: California State University, Fullerton)H-Index: 2
#2Peter Vu (CSUF: California State University, Fullerton)H-Index: 1
Last. Marcelo E. Tolmasky (CSUF: California State University, Fullerton)H-Index: 44
view all 8 authors...
1 CitationsSource
#1M.E. Faure ('KCL': King's College London)
#2Agostino Cilibrizzi ('KCL': King's College London)H-Index: 14
Last. Robert C. Hider ('KCL': King's College London)H-Index: 82
view all 5 authors...
Abstract null null Background null There is growing concern regarding the lack of novel antimicrobial agents and increasing resistance of microorganisms to existing agents. This has stimulated the exploration of novel strategies for infection treatment. null null null Objective null To investigate synergistic interactions between five tetracyclines and tobramycin with an iron chelator (CP762) against two reference strains and nine clinical isolates of Pseudomonas aeruginosa from cystic fibrosis ...
Top fields of study
Intensive care medicine
Antibacterial agent