Inflammatory Bowel Diseases
Papers 9,178
1 page of 918 pages (9,178 results)
#1Kevin Chin Koon Siw (University of Ottawa)H-Index: 1
#2Jake Engel (University of Ottawa)
Last. Jeffrey D. McCurdy (Ottawa Hospital Research Institute)H-Index: 19
view all 7 authors...
Background null Management of perianal fistulas differs based on fistula type. We aimed to assess the ability of diagnostic strategies to differentiate between Crohn's disease (CD) and cryptoglandular disease (CGD) in patients with perianal fistulas. null Methods null We performed a diagnostic accuracy systematic review and meta-analysis. A systematic search of electronic databases was performed from inception through February 2021 for studies assessing a diagnostic test's ability to distinguish...
#1Sumona Bhattacharya (UMAB: University of Maryland, Baltimore)H-Index: 2
#2Gianna Stoleru (UMMC: University of Maryland Medical Center)H-Index: 3
Last. Raymond K. Cross (UMAB: University of Maryland, Baltimore)H-Index: 29
view all 6 authors...
#1Costantino A (UNIMI: University of Milan)
#2Daniele Noviello (UNIMI: University of Milan)H-Index: 3
Last. Flavio Caprioli (UNIMI: University of Milan)H-Index: 40
view all 5 authors...
#1Lester Tsai (UCSD: University of California, San Diego)H-Index: 2
#2Jeffrey D. McCurdy (Ottawa Hospital Research Institute)H-Index: 19
Last. Siddharth Singh (UCSD: University of California, San Diego)H-Index: 71
view all 5 authors...
Background and aims null Perianal Crohn's disease (pCD) is a potentially severe phenotype of CD. We conducted a systematic review with meta-analysis to estimate cumulative incidence, risk factors, and outcomes of pCD in population-based cohort studies. null Methods null Through a systematic literature review through March 1, 2021, we identified population-based inception cohort studies reporting cumulative incidence of perianal disease (primarily abscess and/or fistula) in patients with CD. We e...
#1Karin Westberg (KI: Karolinska Institute)H-Index: 4
#2Ola Olén (KI: Karolinska Institute)H-Index: 25
Last. Caroline Nordenvall (Karolinska University Hospital)H-Index: 17
view all 8 authors...
Background null Restorative surgery after colectomy due to ulcerative colitis (UC) may be performed simultaneously with colectomy (primary) or as a staged procedure. Risk factors for failure after restorative surgery are not fully explored. This study aimed to compare the risk of failure after primary and staged reconstruction. null Methods null This is a national register-based cohort study of all patients 15 to 69 years old in Sweden treated with colectomy due to UC and who received an ileorec...
#1Qiu-Feng Zhao (SHU: Shanghai University)
#2Song Wang (SHU: Shanghai University)
#1Anurag Sachan (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 1
#2Anupam Kumar Singh (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 5
#1Jean-Paul Motta (UFTMP: Federal University of Toulouse Midi-Pyrénées)H-Index: 23
#2Céline Deraison (UFTMP: Federal University of Toulouse Midi-Pyrénées)H-Index: 21
Last. Nathalie Vergnolle (UFTMP: Federal University of Toulouse Midi-Pyrénées)H-Index: 76
view all 5 authors...
A new paradigm has been added for the treatment of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. In addition to resolving symptoms and inflammatory cell activation, the objective of tissue repair and mucosal healing is also now considered a primary goal. In the search of mediators that would be responsible for delayed mucosal healing, protease-activated receptor-1 (PAR-1) has emerged as a most interesting target. Indeed, in Crohn's disease, the endogenous PAR-1 agon...
#1Yunki Y. Yau (UNSW: UNSW Sydney)H-Index: 7
#2Valerie C. Wasinger (UNSW: UNSW Sydney)H-Index: 26
Last. Shaoying N. LeeH-Index: 2
view all 14 authors...
Despite recent developments in therapy for inflammatory bowel diseases (IBDs), there have been limited advances in diagnostic tools available to aid in disease management. A growing body of evidence suggests that there are important host-microbe interactions at the mucosal interface that modulate the inflammatory response in patients with IBD. Additionally, the importance of mucosal integrity and its disruption appears to be important in the pathophysiology and perpetuation of the disease. The a...
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