Inflammatory Bowel Diseases
Papers 9036
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#1Rocio Sedano (UWO: University of Western Ontario)H-Index: 3
#2Tran M NguyenH-Index: 16
Last. Christopher Ma (U of C: University of Calgary)H-Index: 21
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Background null Several indices exist to measure pouchitis disease activity; however, none are fully validated. As an initial step toward creating a validated instrument, we identified pouchitis disease activity indices, examined their operating properties, and assessed their value as outcome measures in clinical trials. null Methods null Electronic databases were searched to identify randomized controlled trials including indices that evaluated clinical, endoscopic, or histologic pouchitis dise...
#1Jens Walldorf (MLU: Martin Luther University of Halle-Wittenberg)H-Index: 9
#2Ulrike von Arnim (Otto-von-Guericke University Magdeburg)H-Index: 14
Last. Philipp A. ReukenH-Index: 11
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#1Sapir Choshen (Shaare Zedek Medical Center)
#2Dan Turner (Shaare Zedek Medical Center)H-Index: 57
Last. Eva Coppenrath (LMU: Ludwig Maximilian University of Munich)H-Index: 19
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Background As part of the prospective multicenter ImageKids study, we aimed to develop and validate the pediatric MRI-based perianal Crohn disease (PEMPAC) index. Methods Children with Crohn disease with any clinical perianal findings underwent pelvic magnetic resonance imaging at 21 sites globally. The site radiologist and 2 central radiologists provided a radiologist global assessment (RGA) on a 100 mm visual analog scale and scored the items selected by a Delphi group of 35 international radi...
#1Tiffany Taft (NU: Northwestern University)H-Index: 16
#2Sarah Quinton (NU: Northwestern University)H-Index: 3
Last. Stephen B. Hanauer (NU: Northwestern University)H-Index: 125
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BACKGROUND Patients with chronic illness are at increased risk for traumatic stress because of medical trauma. Initial studies of posttraumatic stress (PTS) in patients with inflammatory bowel disease (IBD) have found that approximately one-third of patients may experience significant PTS symptoms including flashbacks, nightmares, hypervigilance, disrupted sleep, and low mood. We aim to better characterize PTS in IBD and its relationship with patient outcomes in a large cohort of patients with I...
#1Jurij Hanzel (Ljubljana University Medical Centre)H-Index: 5
#2Erwin Dreesen (Katholieke Universiteit Leuven)H-Index: 14
Last. Ron A. A. MathôtH-Index: 32
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BACKGROUND Higher serum concentrations of vedolizumab have been associated with improved outcomes in inflammatory bowel disease. It is unclear how vedolizumab exposure is linked to endoscopic remission in Crohn disease (CD). We aimed to develop a pharmacokinetic-pharmacodynamic model linking vedolizumab exposure to endoscopic remission in CD. METHODS Data were obtained from the first 110 patients participating in a phase 4 prospective multicenter trial (LOVE-CD; identifier: NC...
#1Heather J. Galipeau (McMaster University)H-Index: 18
#2Alberto Caminero (McMaster University)H-Index: 19
Last. Elena F. Verdu (McMaster University)H-Index: 69
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#1Antonietta Lamazza (Sapienza University of Rome)H-Index: 14
#2Enrico Fiori (Sapienza University of Rome)H-Index: 17
Last. Antonio V. Sterpetti (Sapienza University of Rome)H-Index: 28
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#1Jennie G David (Nationwide Children's Hospital)H-Index: 1
#2Douglas L. Chute (Drexel University)H-Index: 16
Last. Brian P. Daly (Drexel University)H-Index: 16
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#1Lingqi Gong (CSU: Central South University)H-Index: 1
#2Jintao Xiao (CSU: Central South University)
Last. Xiaowei Liu (CSU: Central South University)H-Index: 1
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Background null Exosomes are extensively reported to be strongly associated with many immunologic diseases, including Crohn disease (CD). Meanwhile, the dysfunction of macrophage activation has been proposed to be critical for the pathogenesis of CD. However, it is an unsettled issue whether serum exosomes from CD could activate macrophages and participate in its pathogenesis. Our study intended to clarify the role of CD-derived exosomes on macrophages to elucidate a novel mechanism and possible...
Top fields of study
Inflammatory bowel disease
Crohn's disease
Ulcerative colitis
Diabetes mellitus