Therapeutic Advances in Medical Oncology
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8.17
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556
Papers 855
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Newest
#1Junmiao Wen (Fudan University)H-Index: 7
#2Jiayan Chen (Fudan University)H-Index: 7
Last. Jian ShuH-Index: 1
view all 15 authors...
Background:We aim to assess the prognostic ability of three common lymph node–based staging algorithms, namely, the number of positive lymph nodes (pN), the lymph node ratio (LNR), and log odds of ...
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#1Alice de Malet (University of Paris)
#2Magali Svrcek (Paris IV: Paris-Sorbonne University)
Last. Jérôme Cros (University of Paris)H-Index: 33
view all 11 authors...
Background:Ovarian metastases (OM) of pancreatic adenocarcinoma (PA) (OM-PA) can mimic primary ovarian mucinous carcinoma (POMC) on imaging and histology. These metastases are often symptomatic and...
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Background The objective of this study was to construct a risk classification system integrating cell-free Epstein-Barr virus (cfEBV) DNA with T- and N- categories for better prognostication in nasopharyngeal carcinoma (NPC). Methods Clinical records of 10,149 biopsy-proven, non-metastatic NPC were identified from two cancer centers; this comprised a training (N = 9,259) and two validation cohorts (N = 890; including one randomized controlled phase 3 trial cohort). Adjusted hazard ratio (AHR) me...
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#1Kei Morikawa (St. Marianna University School of Medicine)H-Index: 5
#2Masahiro Iinuma (St. Marianna University School of Medicine)H-Index: 5
Last. Masamichi Mineshita (St. Marianna University School of Medicine)H-Index: 15
view all 6 authors...
Driver mutations in lung cancer have been generally considered mutually exclusive; however, multiple gene screenings have recently become mainstream. Therefore, it is not uncommon to identify two o...
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#1Anna Patrikidou (UCLH: University College Hospital)
#2Thomas Zilli (Geneva College)H-Index: 22
Last. Karim Fizazi (Institut Gustave Roussy)H-Index: 107
view all 6 authors...
Biochemical recurrence is an evolving space in prostate cancer, with increasing multidisciplinary involvement. Androgen deprivation therapy has shown proof of its value in complementing salvage rad...
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#1Amalia Anastasopoulou (UoA: National and Kapodistrian University of Athens)H-Index: 9
#2Panagiotis T. Diamantopoulos (UoA: National and Kapodistrian University of Athens)H-Index: 12
Last. Helen Gogas (UoA: National and Kapodistrian University of Athens)H-Index: 62
view all 7 authors...
Sarcoidosis and sarcoid-like reactions (SLR) have been repeatedly reported in patients with melanoma treated with BRAF and MEK inhibitors. In the current study we present three patients that developed SLR under treatment with BRAF and mitogen-activated protein kinase (MEK) inhibitors for melanoma. Two patients developed mediastinal lymphadenitis with histological features of an SLR while on targeted therapy in the adjuvant setting, whereas one patient with metastatic melanoma developed granuloma...
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#1Christelle Bouchart (ULB: Université libre de Bruxelles)H-Index: 3
#2Jean-Luc Engelholm (ULB: Université libre de Bruxelles)H-Index: 3
Last. Maria Antonietta Bali (ULB: Université libre de Bruxelles)H-Index: 16
view all 15 authors...
Background:Our aim was to evaluate the feasibility and safety of isotoxic high-dose (iHD) stereotactic body radiation therapy (SBRT) in a total neoadjuvant sequence for the treatment of localized p...
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#1Gabriel Rinnerthaler (Paracelsus Private Medical University of Salzburg)H-Index: 14
#2Simon Peter Gampenrieder (Paracelsus Private Medical University of Salzburg)H-Index: 12
Last. Cornelia Hauser-Kronberger (Paracelsus Private Medical University of Salzburg)H-Index: 30
view all 13 authors...
Background:Bendamustine, a medication approved for the treatment of indolent non-Hodgkin lymphoma, has already shown anticancer activity in metastatic breast cancer (MBC). Here, we present the resu...
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#1Dhanusha Sabanathan (Macquarie University)H-Index: 3
#2Maria E. LundH-Index: 11
Last. Howard Gurney (Macquarie University)H-Index: 55
view all 5 authors...
Radioimmunotherapy (i.e., the use of radiolabeled tumor targeting antibodies) is an emerging approach for the diagnosis, therapy, and monitoring of solid tumors. Often using paired agents, each targeting the same tumor molecule, but labelled with an imaging or therapeutic isotope, radioimmunotherapy has achieved promising clinical results in relatively radio-resistant solid tumors such as prostate. Several approaches to optimize therapeutic efficacy, such as dose fractionation and personalized d...
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#1Lorena Incorvaia (University of Palermo)H-Index: 17
#2Giuseppe Badalamenti (University of Palermo)H-Index: 22
Last. Marco Bono (University of Palermo)H-Index: 5
view all 24 authors...
Background Although the gastrointestinal stromal tumor (GIST) genotype is not currently included in risk-stratification systems, a growing body of evidence shows that the pathogenic variant (PV) type and codon location hold a strong prognostic influence on recurrence-free survival (RFS). This information has particular relevance in the adjuvant setting, where an accurate prognostication could help to better identify high-risk tumors and guide clinical decision-making. Materials and Methods Betwe...
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