Frontiers in Molecular Neuroscience
IF
4.06
Papers
2016
Papers 2409
1 page of 241 pages (2,409 results)
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#2Claudia G. Almeida (NOVA: Universidade Nova de Lisboa)H-Index: 15
Last. Sara XapelliH-Index: 19
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#2Casper René Gøtzsche (UCPH: University of Copenhagen)H-Index: 11
Last. David P. D. Woldbye (UCPH: University of Copenhagen)H-Index: 33
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In recent years, gene therapy has been raising hopes towards viable treatment strategy for rare genetic diseases for which there has been almost exclusively supportive treatment. We here review this progress at the preclinical and clinical trial levels as well as market approvals within diseases that specifically affect the brain and spinal cord, including degenerative, developmental, lysosomal storage, and metabolic disorders. The field reached an unprecedented milestone when Zolgensma® (onasem...
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#1Motokazu Uchigashima (Niigata University)H-Index: 1
#2Amy CheungH-Index: 4
Last. Kensuke FutaiH-Index: 18
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Last. Fuzhou Hua (NCU: Nanchang University)H-Index: 7
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Last. Horacio F Cantiello (CONICET: National Scientific and Technical Research Council)H-Index: 2
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#1Kayla Farrell (VT: Virginia Tech)H-Index: 2
#2Madeline Musaus (VT: Virginia Tech)H-Index: 2
Last. Timothy J. Jarome (VT: Virginia Tech)H-Index: 5
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Ubiquitin-proteasome mediated protein degradation has been widely implicated in fear memory formation in the amygdala. However, to date, the protein targets of the proteasome remain largely unknown, limiting our understanding of the functional significance for protein degradation in fear memory formation. Additionally, whether similar proteins are targeted by the proteasome between sexes has yet to be explored. Here, we combined a degradation-specific K48 Tandem Ubiquitin Binding Entity (TUBE) w...
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#2Jun YingH-Index: 2
Last. Fuzhou Hua (NCU: Nanchang University)H-Index: 7
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Top fields of study
Neuroscience
Chemistry
Biochemistry
Medicine
Biology
Cell biology
Synaptic plasticity