The American Journal of Surgical Pathology
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VGLL2-rearranged rhabdomyosarcomas (RMS) are rare low-grade tumors with only favorable outcomes reported to date. We describe 4 patients with VGLL2-rearranged RMS confirmed by molecular studies, who experienced local progression and distant metastases, including 2 with fatal outcomes. Tumors were diagnosed at birth (n=3) or at 12 months of age (n=1), and were all localized at initial diagnosis, but unresectable and therefore managed with chemotherapy and surveillance. Metastatic progression occu...
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#1David Meredith (Brigham and Women's Hospital)H-Index: 41
#2Gregory W. Charville (Stanford University)H-Index: 15
Last. Jason L. Hornick (Brigham and Women's Hospital)H-Index: 73
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#1Takuji Tsuyuki (Aichi Medical University)H-Index: 1
#2Akira SatouH-Index: 8
Last. Toyonori TsuzukiH-Index: 18
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Segmental absence of the intestinal musculature (SAIM) can cause intestinal perforation in adults. However, its prevalence and clinicopathologic features have not been well-described. This study aimed to determine the prevalence of SAIM-associated perforation and characterize its clinicopathologic features. We retrospectively examined 109 cases of intestinal perforation that underwent surgical resection from January 2009 to December 2019. SAIM was defined as the complete absence of the musculari...
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#1Nida Safdar (Harvard University)
#2Jennifer N. StallH-Index: 7
Last. Robert H. YoungH-Index: 96
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#1Alejandro A. Gru (UVA: University of Virginia)H-Index: 9
#2Govind Bhagat (Columbia University)H-Index: 66
Last. Jose A. Plaza (The Ohio State University Wexner Medical Center)H-Index: 1
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#1Lisa M. Rooper (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 15
#2Mena Mansour (WashU: Washington University in St. Louis)H-Index: 7
Last. William H. Westra (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 99
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#1Glorimar Rivera-Colon (Parkland Health & Hospital System)
Last. Elena LucasH-Index: 5
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