Bioactive Materials
Papers 968
1 page of 97 pages (968 results)
#1Fei Feng (CUMS: Capital Medical University)H-Index: 5
#2Mengmeng Chen (CUMS: Capital Medical University)H-Index: 2
Last. Hai Tang (CUMS: Capital Medical University)H-Index: 6
view all 6 authors...
Abstract null null Spinal acrylic bone cements (ABCs) are used clinically for percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) to treat osteoporotic vertebral compression fractures. Product translation of spinal ABC products followed the design control processes including design verification and validation. The bench to bedside translation of the first Chinese spinal ABC product (Alliment®, namely Alliment Cement) approved by National Medical Products Administration of China was investiga...
#1Zhenyu Zhong (HUST: Huazhong University of Science and Technology)H-Index: 1
#2Xiaodan Wu (HUST: Huazhong University of Science and Technology)H-Index: 2
Last. Yingying Du (HUST: Huazhong University of Science and Technology)H-Index: 8
view all 11 authors...
Abstract null null The immune microenvironment induced by biomaterials played vital roles in bone regeneration. Hydroxyapatite (HA) and its ion-substituted derivates represent a large class of core inorganic materials for bone tissue engineering. Although ion substitution was proved to be a potent way to grant HA more biological functions, few studies focused on the immunomodulatory properties of ion-doped HA. Herein, to explore the potential osteoimmunomodulatory effects of ion-doped HA, zinc a...
#1Siqi He (UCD: University of California, Davis)H-Index: 1
#2Tanaya Walimbe (UCD: University of California, Davis)H-Index: 4
Last. Kit S. Lam (UCD: University of California, Davis)H-Index: 62
view all 13 authors...
Abstract null null Diabetic ischemic wound treatment remains a critical clinical challenge. Neovascularization plays a significant role in wound healing during all stages of the tissue repair process. Strategies that enhance angiogenesis and neovascularization and improve ischemic pathology may promote the healing of poor wounds, particularly diabetic wounds in highly ischemic conditions. We previously identified a cyclic peptide LXW7 that specifically binds to integrin αvβ3 on endothelial proge...
#1D Williams (Forest Institute)H-Index: 64
Abstract null null This essay analyzes the scientific evidence that forms the basis of bioactive materials, covering the fundamental understanding of bioactivity phenomena and correlation with the mechanisms of biocompatibility of biomaterials. This is a detailed assessment of performance in areas such as bone-induction, cell adhesion, immunomodulation, thrombogenicity and antimicrobial behavior. Bioactivity is the modulation of biological activity by characteristics of the interfacial region th...
#1Yuxiang Sun (SEU: Southeast University)H-Index: 3
#2Xin Liu (SEU: Southeast University)H-Index: 2
Last. Fei Xiong (SEU: Southeast University)H-Index: 13
view all 10 authors...
Abstract null null SOD-like activity of CeO2 nanoparticles (Ce NPs) is driven by Ce3+/Ce4+, high oxidative stress can oxidize Ce3+ to reduce the ratio of Ce3+/Ce4+, inactivating the SOD activity of Ce NPs. Herein, we found Au@Ce NPs, assembled by Au NPs and Ce NPs, exhibited high-performance of SOD mimetic enzyme activity even upon the oxidation of H2O2. Ce NPs supported by nano-Au can acquire the electrons from Au NPs through the enhanced localized surface plasmon resonance (LSPR), maintaining ...
#1Fangping Chen (ECUST: East China University of Science and Technology)H-Index: 11
#2Qing Liang (ECUST: East China University of Science and Technology)H-Index: 1
Last. Changsheng Liu (ECUST: East China University of Science and Technology)H-Index: 54
view all 7 authors...
Abstract null null Osteoporosis is a reduction in skeletal mass due to the decrease of osteogenic ability and the activation of the osteoclastic function. Inhibiting bone resorption and accelerating the new bone formation is a promising strategy to repair the bone defect of osteoporosis. In this study, we first systematically investigated the roles of Chinese medicine Asperosaponin VI (ASP VI) on osteogenic mineralization of BMSCs and osteoclastogenesis of BMMs, and then explored the synergistic...
#1Jiaxin TianH-Index: 2
#2Xu Song (SCU: Sichuan University)H-Index: 1
Last. Minghui Wang (SCU: Sichuan University)H-Index: 1
view all 11 authors...
Abstract null null Combination products with a wide range of clinical applications represent a unique class of medical products that are composed of more than a singular medical device or drug/biological product. The product research and development, clinical translation as well as regulatory evaluation of combination products are complex and challenging. This review firstly introduced the origin, definition and designation of combination products. Key areas of systematic regulatory review on th...
#1Caroline D. Hoemann (Polytechnique Montréal)H-Index: 3
#1Caroline D. Hoemann (Polytechnique Montréal)H-Index: 35
Last. Basil D. Favis (Polytechnique Montréal)H-Index: 52
view all 6 authors...
Abstract null null This study tested whether osseous integration into poly (e-caprolactone) (PCL) bioplastic scaffolds with fully-interconnecting 155 ± 8 μm pores is enhanced by an adhesive, non-inflammatory 99% degree of deacetylation (DDA) chitosan coating (99-PCL), or further incorporation of pro-inflammatory 83% DDA chitosan microparticles (83-99-PCL) to accelerate angiogenesis. New Zealand White rabbit osteochondral knee defects were press-fit with PCL, 99-PCL, 83-99-PCL, or allowed to blee...
#1Dawei Jin (SJTU: Shanghai Jiao Tong University)H-Index: 4
#2Shuofei Yang (SJTU: Shanghai Jiao Tong University)
Last. Haizhu Kuang (SZU: Shenzhen University)H-Index: 1
view all 5 authors...
Abstract null null Pericardial barrier destruction, inflammatory cell infiltration, and fibrous tissue hyperplasia, trigger adhesions after cardiac surgery. There are few anti-adhesion materials that are both functional and sutureable for pericardial reconstruction. Besides, a few studies have reported on the mechanism of preventing pericardial adhesion. Herein, a functional barrier membrane with sutureability was developed via a modified electrospinning method. It was composed of poly( l -lacti...
#1Huaiyu Shi (SU: Syracuse University)H-Index: 2
#2Xiangjun Wu (SU: Syracuse University)
Last. Zhen Ma (SU: Syracuse University)H-Index: 17
view all 10 authors...
Abstract null null Focal adhesion complexes function as the mediators of cell-extracellular matrix interactions to sense and transmit the extracellular signals. Previous studies have demonstrated that cardiomyocyte focal adhesions can be modulated by surface topographic features. However, the response of focal adhesions to dynamic surface topographic changes remains underexplored. To study this dynamic responsiveness of focal adhesions, we utilized a shape memory polymer-based substrate that can...
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