European Urology Oncology
Papers
331
Papers 463
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#1Brandon A. Mahal (UM: University of Miami)H-Index: 28
#2Travis GerkeH-Index: 16
Last. Lorelei A. Mucci (Harvard University)H-Index: 86
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Abstract null null Context null Prostate cancer (PCa) is a complex disease that disproportionately impacts Black men in the USA. The structural factors that drive heterogeneous outcomes for patients of differing backgrounds are probably the same ones that result in population-level disparities. The relative contribution of drivers along the PCa disease continuum is an active area of investigation and debate. null null null Objective null To critically synthesize the available evidence on PCa dis...
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#1Adam K. Aragaki (Johns Hopkins University)
#2Yuezhou Jing (Johns Hopkins University)
Last. Burles A. Johnson (Johns Hopkins University)H-Index: 5
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Abstract null null Background null There is a great need to identify biomarkers that can accurately identify patients who will obtain the most clinical benefit from immune checkpoint inhibitor (ICI) therapy. While high intratumoral B cell gene expression correlated with an ICI response in melanoma, whether it adds predictive value in other cancers is unknown. null null null Objective null To examine the relationship between B cell gene signature (BCGS) expression and overall survival (OS) follow...
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#1Hendrik Van Poppel (Katholieke Universiteit Leuven)H-Index: 82
#2Renée Hogenhout (Erasmus University Medical Center)H-Index: 1
Last. Monique J. Roobol (Erasmus University Medical Center)H-Index: 76
view all 6 authors...
Abstract null null Context null Overdiagnosis as the argument to stop prostate cancer (PCa) screening is less valid since the introduction of new technologies such as risk calculators (RCs) and magnetic resonance imaging (MRI). These new technologies result in fewer unnecessary biopsy procedures and fewer cases of both overdiagnosis and underdetection. Therefore, we can now adequately respond to the growing and urgent need for a structured risk assessment to detect PCa early. null null null Obje...
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#1Tessel E. Galesloot (Radboud University Nijmegen)H-Index: 22
#2Anne J. Grotenhuis (Radboud University Nijmegen)H-Index: 14
Last. Neil Fleshner (Princess Margaret Cancer Centre)H-Index: 73
view all 19 authors...
BACKGROUND Non-muscle-invasive bladder cancer (NMIBC) is characterized by frequent recurrences and a risk of progression in stage and grade. Increased knowledge of underlying biological mechanisms is needed. OBJECTIVE To identify single nucleotide polymorphisms (SNPs) associated with recurrence-free (RFS) and progression-free (PFS) survival in NMIBC. DESIGN, SETTING, AND PARTICIPANTS We analyzed outcome data from 3400 newly diagnosed NMIBC patients from the Netherlands, the UK, Canada, and Spain...
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#1M. KuppenH-Index: 4
#2Hans M. WestgeestH-Index: 6
Last. Winald R. Gerritsen (Radboud University Nijmegen)H-Index: 30
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Abstract Background Cross resistance between androgen-receptor targeting therapies (ARTs) (abiraterone acetate plus prednisone [ABI + P] or enzalutamide [ENZ]) for treatment of metastatic castration-resistant prostate cancer (mCRPC) may affect responses to second ART (ART2). Objective To establish treatment duration and prostate-specific antigen (PSA) response of ART2 in real-world mCRPC patients treated with or without other life-prolonging drugs (LPDs; ie, docetaxel, cabazitaxel, or radium-223...
1 CitationsSource
#1Shahrokh F. Shariat (Medical University of Vienna)H-Index: 132
#2Paolo GonteroH-Index: 52
Last. James W.F. Catto (University of Sheffield)H-Index: 73
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Abstract A relatively young (64-yr old) long-term heavy smoker but otherwise very healthy man is diagnosed with a primary unifocal left-side tumour (urothelial, T1 high grade), but no lymphovascular invasion and no variant histology. We discuss whether treatment with intravesical bacillus Calmette-Guerin vaccine will be sufficient or early radical cystectomy is at least equally preferred regarding patient benefit, safety, and quality of life. Patient summary A patient with a single high-grade T1...
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#1Anne Sofie FribergH-Index: 2
Last. Klaus BrassoH-Index: 28
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Abstract Background Development of depression in prostate cancer patients depends on multiple disease- and patient-related factors. Objective To investigate the risk of depression following radical prostatectomy focussing on the impact of surgery and subsequent treatment with salvage radiation or androgen deprivation therapy. Design, setting, and participants A population-based cohort study of 5570 men who underwent radical prostatectomy in Denmark from 1998 to 2011 was identified in the Danish ...
3 CitationsSource
#1Armando Stabile (UniSR: Vita-Salute San Raffaele University)H-Index: 17
#2Elio Mazzone (UniSR: Vita-Salute San Raffaele University)H-Index: 11
Last. Samir S. Taneja (NYU: New York University)H-Index: 69
view all 10 authors...
Abstract Context The diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) for prostate cancer (PCa) diagnosis has been extensively explored. Little is known about the prognostic value of mpMRI suspicion scores and other quantitative mpMRI information. Objective To systematically review the current literature assessing the relationship between pretreatment mpMRI and oncological outcomes after primary treatment for PCa to assess the role of mpMRI as a prognostic tool. Evidence...
2 CitationsSource
#1Alessia Cimadamore (United Hospitals)H-Index: 17
#2Liang Cheng (IU: Indiana University)H-Index: 132
Last. Rodolfo Montironi (United Hospitals)H-Index: 96
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Abstract Context Whole-mount histopathology, that is, large format histology or whole-mount sectioning, refers to the histopathological examination of tissue sections from specimens processed with large tissue cassette. In some institutions, it is applied routinely to specimens with genitourinary cancers. Objective To give an overview of the application of the large format histology to the morphological examination of the radical prostatectomy (RP) specimens. Evidence acquisition A comprehensive...
1 CitationsSource
#1Mikael Anttinen (TYKS: Turku University Hospital)H-Index: 3
#2Otto Ettala (TYKS: Turku University Hospital)H-Index: 11
Last. Peter J. Boström (TYKS: Turku University Hospital)H-Index: 27
view all 22 authors...
Abstract Background Computed tomography (CT) and bone scintigraphy (BS) are the imaging modalities currently used for distant metastasis staging of prostate cancer (PCa). Objective To compare standard staging modalities with newer and potentially more accurate imaging modalities. Design, setting, and participants This prospective, single-centre trial (NCT03537391) enrolled 80 patients with newly diagnosed high-risk PCa (International Society of Urological Pathology grade group ≥3 and/or prostate...
8 CitationsSource
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Cancer
Oncology
Prostatectomy
Prostate cancer
Bladder cancer
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