BMJ open diabetes research & care
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3.18
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618
Papers 985
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#1Masayuki YamanouchiH-Index: 17
#2Kengo Furuichi (Kanazawa Medical University)H-Index: 6
Last. Yasunori Iwata (Kanazawa University)H-Index: 27
view all 33 authors...
Introduction null Data on the association between longitudinal trajectory patterns of albuminuria and subsequent end-stage kidney disease (ESKD) and all-cause mortality in diabetic kidney disease (DKD) are sparse. null Research design and methods null Drawing on nationally representative data of 329 patients with biopsy-proven DKD and an estimated glomerular filtration rate above 30 mL/min/1.73 m2 at the time of biopsy, we used joint latent class mixed models to identify different 2-year traject...
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#1Fariba Ahmadizar (EUR: Erasmus University Rotterdam)H-Index: 15
#2Kan Wang (EUR: Erasmus University Rotterdam)
Last. Maryam Kavousi (EUR: Erasmus University Rotterdam)H-Index: 62
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Introduction null Data on sex-specific lifetime risk of cardiovascular disease (CVD) across the glycemic spectrum, in particular in impaired fasting glucose (IFG) state, are scarce. Whether overweight/obesity modifies the CVD burden also remains unclear. null Research design and methods null Using a prospective population-based Rotterdam Study, normoglycemia, IFG, and type 2 diabetes mellitus (T2D) were defined. First incident cases of coronary heart disease, heart failure, and stroke during a f...
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#1Shiro Tanaka (Kyoto University)H-Index: 34
#2Jakob Langer (Novo Nordisk)H-Index: 12
Last. Rei Aida (Kyoto University)H-Index: 2
view all 13 authors...
Introduction null Cost-effectiveness analyses are becoming increasingly important in Japan following the introduction of a health technology assessment scheme. The study objective was to develop an economic model to evaluate the cost-effectiveness of two interventions for type 2 diabetes in a Japanese population. null Research design and methods null The Japan Diabetes Complications Study/Japanese Elderly Diabetes Intervention Trial risk engine (JJRE) Cost-Effectiveness Model (JJCEM) was develop...
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#1Junfeng Zhang (Ha Tai: Xiamen University)
#2Qiaoyan Xu (Ha Tai: Xiamen University)
Last. Zhibin Li (Ha Tai: Xiamen University)H-Index: 10
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INTRODUCTION We aimed to evaluate the joint associations of metabolically healthy abdominal obesity (MHAO) with non-alcoholic fatty liver disease (NAFLD) on risks of diabetes and prediabetes. RESEARCH DESIGN AND METHODS Baseline information of 1318 adults with abdominal obesity (waist circumference ≥90 cm for men and 80 cm for women) from an ongoing cohort study in Xiamen, China were analyzed. Metabolic health was identified as none of the criteria of metabolism syndrome, except for obesity, was...
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#1Efe Yagiz Akinci (UM: University of Michigan)
#2Sabine Boutros (UM: University of Michigan)
Last. Elif A. Oral (UM: University of Michigan)H-Index: 31
view all 9 authors...
Provocative rodent studies taken together with cross-sectional human epidemiological data have shown that there may be a cross-talk between circulating leptin levels and whole-body iron metabolism.1 2 In this study, we aim to discover the effects of recombinant leptin administration on iron parameters in patients with partial lipodystrophy. We studied serum samples from 19 patients with partial lipodystrophy (median age: 42 years, IQR: 34–57, male/female: 3/16) gathered from an open-label study ...
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#1Jana Anderson (Glas.: University of Glasgow)H-Index: 18
#2Paul Welsh (Glas.: University of Glasgow)H-Index: 62
Last. James G. Boyle (Glas.: University of Glasgow)H-Index: 9
view all 17 authors...
Introduction: Early detection and treatment of diabetes as well as its prevention help lessen longer-term complications. We determined the prevalence of pre-diabetes and undiagnosed diabetes in the UK Biobank and standardized the results to the UK general population. Research design and methods: This cross-sectional study analyzed baseline UK Biobank data on plasma glycated hemoglobin (HbA1c) to compare the prevalence of pre-diabetes and undiagnosed diabetes mellitus in white, South Asian, black...
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#1Danielle E. HaslamH-Index: 6
#2Liming Liang (Harvard University)H-Index: 74
Last. David T.W. Wong (UCLA: University of California, Los Angeles)H-Index: 95
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INTRODUCTION We investigated whether network analysis revealed clusters of coregulated metabolites associated with prevalent type 2 diabetes (T2D) among Puerto Rican adults. RESEARCH DESIGN AND METHODS We used liquid chromatography-mass spectrometry to measure fasting plasma metabolites (>600) among participants aged 40-75 years in the Boston Puerto Rican Health Study (BPRHS; discovery) and San Juan Overweight Adult Longitudinal Study (SOALS; replication), with (n=357; n=77) and without (n=322; ...
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#1Sian Louise Grace (University of Exeter)
Last. Timothy J. McDonald (University of Exeter)H-Index: 32
view all 4 authors...
INTRODUCTION Zinc transporter 8 autoantibodies (ZnT8A) are biomarkers of beta cell autoimmunity in type 1 diabetes that have become more widely available to clinicians in recent years. Robust control population-defined thresholds are essential to ensure high clinical specificity in islet autoantibody testing. We aimed to determine the optimal cut-offs for ZnT8A testing. RESEARCH DESIGN AND METHODS 97.5th and 99th centile cut-offs were determined using residual clinical sera from 1559 controls ag...
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#1Elizabeth M. Vaughan (BCM: Baylor College of Medicine)H-Index: 6
#2Aanand D. Naik (Michael E. DeBakey Veterans Affairs Medical Center in Houston)H-Index: 39
Last. John P. Foreyt (BCM: Baylor College of Medicine)H-Index: 67
view all 9 authors...
INTRODUCTION Community clinics often face pragmatic barriers, hindering program initiation and replication of controlled research trial results. Mentoring is a potential strategy to overcome these barriers. We piloted an in-person and telehealth mentoring strategy to implement the Telehealth-supported, Integrated Community Health Workers (CHWs), Medication-access, group visit Education (TIME) program in a community clinic. RESEARCH DESIGN AND METHODS Participants (n=55) were low-income Latino(a)...
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