Journal of investigative medicine high impact case reports
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#1Natia Murvelashvili (UTSW: University of Texas Southwestern Medical Center)
#2Alex H. Tessnow (UTSW: University of Texas Southwestern Medical Center)H-Index: 2
The emergence of a novel coronavirus and global pandemic raised the need for the rapid development of new vaccines to reduce the morbidity and mortality associated with Covid-19. Common side effects of these vaccines such as myalgia, arthralgia, nausea, fatigue, and injection site reaction are usually self-resolving. Recognition of other potential adverse effects of these novel vaccines is important due to their rapid and widespread distribution. We report a case of a 51-year-old man admitted to...
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#1Sumit PatelH-Index: 2
#2Sasmit Roy (UVA: University of Virginia)H-Index: 1
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Immune checkpoint inhibitors (ICIs) are novel anticancer therapy approved in multiple tumors and their use is rapidly increasing. They are associated with various systemic side effects that are immune-mediated and clinically coined as "immune-related adverse effects" (irAE). Hyponatremia is a possible side effect in patients receiving ICIs. Fever is another side effect that is mostly non-infectious. There are different mechanisms leading to hyponatremia in patients on ICIs, which could be (1) hy...
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#1Kristen Farraj (Nassau University Medical Center)H-Index: 1
#2Atul Sinha (Nassau University Medical Center)
Last. Krishnaiyer Subramani (Nassau University Medical Center)H-Index: 6
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While diverticulosis is a common phenomenon in the large intestine, it is a rare disease found in the small intestine accounting for only 0.06% to 1.3% of cases. Although most cases are asymptomatic, roughly 30% to 40%, it is crucial that it is on the differential of acute abdominal pain as it can be life-threatening and potentially require surgical management. Here, we describe a case of a 61-year-old Hispanic man who was found to have a perforated jejunal diverticula after initially presenting...
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#1Abdulbaril Olagunju (Creighton University)
#2Nawfal Mihyawi (Creighton University)H-Index: 1
Last. Mehrdad Saririan (Creighton University)H-Index: 2
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Secundum atrial septal defect (ASD) is the most common type of ASD. Symptoms including dyspnea on exertion usually manifest in the third and fourth decade of life. The transcatheter closure is the treatment of choice for secundum ASD. The transfemoral venous approach has been the mainstay. However, this approach can be challenging or impossible in patients with congenital absence or interruption of the inferior vena cava (IVC). The latter has been reported in patients with situs ambiguus and inv...
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#1Amar S. Shah (Kern Medical Center)
#2Valerie F. Civelli (Kern Medical Center)
Last. Arash Heidari (Kern Medical Center)H-Index: 7
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Genomic variants of the hepatitis B virus (HBV) preS/S protein are well-known to occur. Typically, immunity is gained through recovered HBV infection or by immunization. Very rarely, there are cert...
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#1Prarthana Jain (MUSC: Medical University of South Carolina)
#2Sagar Patel (MUSC: Medical University of South Carolina)
Last. Katherine Silver (MUSC: Medical University of South Carolina)H-Index: 2
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Nodular regenerative hyperplasia (NRH) is a rare disease that is characterized by benign transformation of the hepatic parenchyma into small nodules with little to no fibrosis. Nodular regenerative...
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Patients chronically infected with hepatitis B virus (HBV) may travel to areas with high endemicity of malaria. The overlap between malaria and HBV infection can be clinically severe and present a diagnostic challenge as both diseases manifest similar symptoms. This case describes a fatal case of a 43-year-old man with chronic HBV infected with Plasmodium falciparum malaria that presents as acute kidney injury (AKI) and jaundice following a trip to malaria-endemic region. Despite administering a...
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#1Razwana Khanam (University of Pittsburgh)
#2Pranali Santhoshini Pachika (University of Pittsburgh)
Last. Proshikha Saha (Sir Salimullah Medical College)
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Neuroendocrine tumors usually originate from the neuroendocrine cells of gastrointestinal tract and their presence in the liver is mostly in the form of metastases. A primary neuroendocrine tumor in the liver concomitantly with hepatocellular carcinoma is an infrequent phenomenon. We present a 66-year-old woman with a remote history of breast cancer coming with postprandial fullness, later found to have multiple liver masses. After a thorough investigation, she was found to have a combined type ...
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#1Manasa Dondapati (St. George's University)
#2Jonathan Vincent M Reyes (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 1
Last. Joseph Lieber (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 3
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Rhabdomyosarcoma is a malignant soft tissue sarcoma of primitive mesenchymal cells, showing varying degrees of striated skeletal muscle cell differentiation. It is a very common cancer of childhood and adolescence, but rarely seen in the adult population. Here, we present a case of a 33-year-old male presented with a poorly differentiated desmin positive alveolar rhabdomyosarcoma in the left arm. The prognosis of alveolar rhabdomyosarcoma in adults is very poor, frequently detected at advanced s...
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#1John Dayco (WSU: Wayne State University)
#2Zeinab El-Reda (WSU: Wayne State University)
Last. Shaheena Raheem (WSU: Wayne State University)
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As more patients recover from COVID-19 infection, long-term complications are beginning to arise. Our case report will explore a debilitating long-term complication, Post-COVID Interstitial Lung Disease (PC-ILD). We will introduce a patient who developed PC-ILD in the setting of diffuse large B-cell lymphoma, outlining a difficult hospital course, including a positive COVID-19 polymerase chain reaction (PCR) for more than 3 months. We will then discuss the human body's physiological response to ...
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