Emerging microbes & infections
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#1Jianqing Zhao (HAU: Huazhong Agricultural University)H-Index: 1
#2Zhang Yijing (HAU: Huazhong Agricultural University)
Last. Ming Zhou (HAU: Huazhong Agricultural University)H-Index: 12
view all 9 authors...
Rabies remains a public health threat in most parts of the world. Dogs, especially stray dogs, are the main sources of rabies transmission in developing countries, while wild animals are primarily responsible for the spread of rabies in developed countries and play an emerging role in rabies transmission in developing countries. Oral vaccination is the most practical method for rabies control in these animals, and the greatest challenge for oral vaccination is the hostile environment and large q...
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#2Erik ArabyanH-Index: 6
Last. Hovakim ZakaryanH-Index: 10
view all 20 authors...
African swine fever virus (ASFV) is the causal agent of a highly fatal disease of domestic swine for which no effective vaccines and antiviral drugs are available. Recently, it has been shown that microtubule-targeting agents hamper the infection cycle of different viruses, raising the idea that microtubules can be potential host targets for antiviral drug development. In this study, we conducted in silico screening against the colchicine binding site (CBS) of tubulin and found three new compoun...
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#1Andreina Baj (University of Insubria)H-Index: 16
#2Federica NovazziH-Index: 6
Last. Riccardo CapuanoH-Index: 2
view all 15 authors...
We report 11 cases of SARS-CoV-2 infection in healthcare workers (HCW) naive for COVID-19 and seropositive after the second dose of the BNT162b2 mRNA vaccine. Based on voluntary-based surveillance,...
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#1Víctor Neira (University of Chile)H-Index: 7
#2Barbara Brito (UTS: University of Technology, Sydney)H-Index: 12
Last. Rafael A. Medina (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 15
view all 22 authors...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected in domestic and wild cats. However, little is known about natural viral infections of domestic cats, although their importance for modelling disease spread, informing strategies for managing positive human-animal relationships and disease prevention. Here, we describe the SARS-CoV-2 infection in a household of two human adults and sibling cats (one male and two females) using real-time RT-PCR, an ELISA test, viral seq...
11 CitationsSource
#1Yun Liao (Peking Union Medical College)H-Index: 14
#2Ying Zhang (Peking Union Medical College)H-Index: 18
Last. Qihan Li (Peking Union Medical College)H-Index: 21
view all 13 authors...
Neutralizing antibodies in the subjects of an inactivated SARS-CoV-2 vaccine clinical trial showed a decreasing trend over months. An investigation studying the third immunization suggested that the waning of neutralizing antibodies in individuals administered two doses of inactivated vaccine does not mean the disappearance of immunity.
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#1Pierre H. Boyer (UDS: University of Strasbourg)H-Index: 4
Last. Benoît Jaulhac (UDS: University of Strasbourg)H-Index: 31
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Neoehrlichia mikurensis is an intracellular bacterium transmitted in Europe and Asia by ticks of the Ixodes ricinus complex. Interest in this bacterium has increased since it was demonstrated to be responsible for febrile syndromes in patients. To date, most clinical cases have been reported in northern Europe, but case series have also been described in central Europe and China. Notably, thrombotic events occurred during the course of the disease.We investigated the presence of N. mikurensis in...
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#1Liubov I. Kozlovskaya (MSMU: I.M. Sechenov First Moscow State Medical University)H-Index: 15
#2Anastasia Piniaeva (RAS: Russian Academy of Sciences)H-Index: 1
Last. Liliya P Antonova (RAS: Russian Academy of Sciences)
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AbstractThe unprecedented in recent history global COVID-19 pandemic urged the implementation of all existing vaccine platforms to ensure the availability of the vaccines against COVID-19 to every country in the world. Despite the multitude of high-quality papers describing clinical trials of different vaccine products, basic detailed data on general toxicity, reproductive toxicity, immunogenicity, protective efficacy and durability of immune response in animal models are scarce. Here, we develo...
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#1C. Joaquín Cáceres (UGA: University of Georgia)H-Index: 2
#2Yanmei Hu (UA: University of Arizona)H-Index: 14
Last. Qing-Yu Zhang (UA: University of Arizona)
view all 0 authors...
Seasonal influenza A virus (IAV) infections are among most important global health problems. FDA-approved antiviral therapies against IAV include neuraminidases inhibitors, M2 inhibitors, and polymerase inhibitor baloxavir. Resistance against adamantanes (amantadine and rimantadine) is widespread as virtually all IAV strains currently circulating in the human population are resistant to adamantanes through the acquisition of the S31N mutation. The neuraminidase inhibitor resistant strains also c...
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Shigella sonnei (S. sonnei) is sometimes sexually transmitted. Men, who have sex with men (MSM), may have sexual behaviours different from heterosexual population, and thus may be at risk for S. so...
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AbstractAvian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1 (NS1) of influenza viruses is an essential interferon antagonist. It commonly consists of 230 amino acids, but variations in the disordered C-terminus resulted in truncation or extension of NS1 with a possible impact on virus fitness in mammals. Here, we analysed NS1 sequences from 1902 to 202...
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