Journal of diabetes & metabolism
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ong-term hyperglycemia can impair renal microvessels and lead to diabetic nephropathy (DN). Early treatment can delay or prevent its progression. Efficacy of monoclonal antibody (mAb) therapies for human diseases can often be tested only in nonhuman primates (NHPs) but no other species due to lack of human mAb cross-reactivity. To test if DN in NHPs is similar to the human disease, this study analyzed the blood and urine biochemistry data from a large pool (n=129) of cynomolgus monkeys (Macacafa...
Background: Ensuring the quality of pharmaceutical services in hospitals is an integral aspect of ensuring the quality of health care. In this regard, it has long been proven that adoption of the concept of pharmaceutical care is essential to improve the quality of pharmaceutical services. Hence, this study aimed to assess type 2 Diabetes mellitus (DM) patients’ satisfaction with pharmacy services in Wollega university referral hospital, West Ethiopia. Method: Descriptive cross-sectional study d...
Diabetes prevalence is increasing, according to the International Diabetes Federation report in 2013, 382 Millions have diabetes, and the number is expected to rise beyond 592 million by 2035, an increase of approximately 55%. Type2 Diabetes Mellitus(T2DM) is associated with Obesity, Dyslipidemia, and Hypertension. Hypertension plays a major role in the development of Cardiovascular Disease (CVD). The prevalence of hypertension is higher in people with T2DM than the general public. Macro vascula...
We introduced the hospital policy on the management of severe symptomatic hyponatraemia (SSH), with hypertonic saline (HS) of 1.8% and 5% saline in 2017. This is one of the few UK centres to offer this treatment, therefore the evidence is limited. The policy was based on European and American guidelines (1) (2). Objectives To study the adherence, and effectiveness, of this guideline in managing patients with SSH. Methods Patients were identified using the Biochemistry tracking system between 01/...
Background: This is a prospective, open-label, drug and dose-controlled study. The primary objective of this study is to evaluate the safety and efficacy of cannabidiol (CBD) sublingual tablets for the treatment of patients with chronic diabetic neuropathic pain. The secondary objects are to evaluate the impact of CBD tablets on sleep quality and anxiety. We describe the effectiveness data at the completion of a 21-day study. Methods: Subjects who met all inclusion/exclusion criteria and met the...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver disease which may progress to non-alcoholic steatohepatitis (NASH). Currently there are no therapeutic strategies for such disease. Only lifestyle modification through diet and exercise were proven to afford some benefit in patients with NAFLD. No pharmacologic agents have so far been approved for the treatment of NAFLD or NASH. Therefore, most clinical efforts have been directed at treating the components...
This study took place from November 2019-March 2020. Blood samples were collected from patients after informed consent by finger pricking. Stool samples were examined using normal saline and the Kato-Katz technique for the presence and intensity of IPs. Thick blood films were prepared, Giemsa-stained and examined under x100 to detect the presence of parasites and estimate GMPD. Hb values were determined using a haemoglobinometer. Data was analysed using SPSS version 23 and the significance level...
Background: Type I diabetes mellitus affects the quality of life of children. Measuring the quality of life of such patients would be important for evaluating treatment outcomes and decision making. Objective: the aim of this study is to assess the quality of life of children with type I diabetes mellitus attending the pediatric endocrine clinic of a tertiary hospital. Patients and Methods: This study is a hospital-based descriptive cross-sectional study conducted between April 31 and July 1, 20...
The incidence of obesity is increasing in mammoth proportions so much so that associated comorbidity T2DM incidence is increasing markedly that we had to coin a term Diabesity to target both together. Earlier trying to review etiopathogenesis of both obesity and type 2 DM we found that whatever drugs that are formulated usually do not work with some complications and till now other than bariatric surgery we have no permanent cure for long term maintenance.Further T2DM might be a disease of 2 eti...
Journal of Diabetes & Metabolism has been started in the year 2010 and it released its first volume in the same year. Till now, the journal has released 10 volumes by the end of 2020 and is successfully running its 12th Volume.
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Top fields of study
Endocrinology
Type 2 diabetes
Insulin
Diabetes mellitus
Medicine