Journal of the Pancreas
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Context Vildagliptin is an oral anti-diabetic agent of the dipeptidyl-peptidase 4 inhibitor (DPP-4i) class of drugs. Together with glucagon-like peptide analogs (GLP1a), DPP-4i drugs are being known as incretin-based therapies (IBT). Results of clinical trials are conflicted about a potential association between IBT and acute pancreatitis. Case Reports We present the history, clinical progress, and diagnostic findings of two cases of acute pancreatitis occurred in a patient treated with vildagli...
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#1Manami IkemuneH-Index: 2
#2Kazushige UchidaH-Index: 30
Last. Kazuichi OkazakiH-Index: 85
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Introduction Type 1 autoimmune pancreatitis is a chronic fibro-inflammatory disorder. We previously reported the involvement of M2 macrophages and basophils in autoimmune pancreatitis. It is reported that Group 2 innate lymphoid cells (ILC2s) and basophils play an important role in asthma. Thus, this study investigated the roles of innate lymphoid cells in autoimmune pancreatitis. Subjects and methods We recruited 28 patients with autoimmune pancreatitis (25 men and 3 women; mean age, 68.4 years...
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Teratoma is a common germ cell tumor, which most cases can be diagnosed by imaging examination. At present, surgical treatment is the main treatment method, but the occurrence of teratoma in some cases brings lots of trouble. Our case was a 2-month-old baby boy with abdominal distension as main manifestation at the beginning, and was diagnosed by CT as a large mass in the left abdomen (teratoma). The mass adjoined closely to the pancreas and brought much complexity for surgical excision. We ther...
Neuroendocrine tumors are a heterogenous group of tumors arising most commonly in the gastrointestinal tract and in the bronchus pulmonary tree. Other rare sites include parathyroid and adrenal glands. Peripancreatic lymph-node as a primary site for neuroendocrine tumor is extremely rare and no reports could be seen in literature. A thorough search of literature found a case report of a primary neuroendocrine tumor of the inguinal lymph-node. Reporting the case report of a 48year old man who pre...
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Context Pancreatic cancer is the fourth most common cause of cancer death in Europe characterized by disappointing tumor response rates and high levels of resistance to standard treatments. Understanding genomic variations in pancreatic cancer is crucial, as they are known to contribute to pancreatic carcinogenesis and may provide fundamental knowledge for new and effective treatment strategies. Objective The main purpose of this exploratory study was to try to characterize the genomic profile o...
Introduction Central pontine myelinolysis (CPM) is a rare osmotic demyelination syndrome. Myelinolysis following patients with acute pancreatitis (AP) is extremely rare. To the best of our knowledge, only two cases have been reported in prior literatures. However, the associated mechanisms on patients with CPM secondary to AP have remained unclear. Patient concerns (1) A 58-year-old woman, with upper abdomen pain complicating nausea and vomiting for ten days, had a fever and abdominal pain (firs...
Introduction Solid pseudopapillary tumours (SPN) of pancreas are increasingly being diagnosed and reported. Understanding the management of these tumours is getting better but still there are many unanswered questions. Materials and Methods this is a retrospective analysis of prospectively maintained surgical database at the department of GI Surgery and GI Oncology, Medanta, Gurugram, Haryana. The clinicopathological and surgical parameters of 34 patients who underwent surgery for SPN, over a 10...
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Top fields of study
Surgery
Pancreatitis
Pancreas
Context (language use)
Pancreatic cancer
Medicine