China journal of Chinese materia medica
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#1Zhen-Dong Liu (Henan University)
#2Jin-Xu Lan (Henan University)
Last. Sui-Qing Chen (Henan University)H-Index: 3
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As a local variety of medicinal material, Citri Trifoliatae Fructus is widely used in many places, whereas its harvest time remains unclear. Therefore, studying its harvest time can make more reasonable use of this medicinal material. In this study, we determined the flavonoids content and compared the color of Citri Trifoliatae Fructus harvested in different time, aiming to guide the harvest of this medicinal material. The fresh fruits of Citrus trifoliata were collected from Xinxiang city, Hen...
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#1Bing-Zhi Ma (CJFH: China-Japan Friendship Hospital)H-Index: 4
#2Dong Li (CJFH: China-Japan Friendship Hospital)
Last. Xiao Liu (CJFH: China-Japan Friendship Hospital)
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This paper aims to explore active components and mechanism of Scutellariae Radix(SR)-Phellodendri Chinensis Cortex(PCC) drug pair in treatment of psoriasis by network pharmacology and molecular docking. Specifically, the chemical components of SR and PCC were retrieved from literature and TCMSP, as well as targets of these components from PharmMapper and UniProt, and the targets related to psoriasis from OMIM, TTD, PharmGkb, and DrugBank. Then the chemical component-medicinal target, protein-pro...
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#2Fei Teng (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)
Last. Wei-Hong Feng (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 5
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Based on the textual research on literature, the key information of Wenjing Decoction were tested and identified, and 15 batches of lyophilized powder samples of Wenjing Decoction were prepared. The specific components, including paeoniflorin, glycyrrhizin, ginsenosides(Rg_1, Re and Rb_1), glycyrrhizic acid, and paeonol, were used as indexes to establish the HPLC method for quantitative evaluation, and the content ranges and transfer rates of these components were determined. The results showed ...
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#1Shu-di Li (Henan University)
#2Su-Ling Li (Henan University)
Last. Pei-Pei Yuan (Henan University)
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The present study explored the mechanism of action of Gynostemma pentaphyllum in the treatment of metabolism associa-ted fatty liver disease(MAFLD) by network pharmacology and molecular docking. The main active components and action targets of G. pentaphyllum were collected from TCMSP. Disease-related targets were obtained from GeneCards, OMIM and TTD, and the common targets of the three databases were screened out, which were converted to the genes with standard names by UniProt. The drug-disea...
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#1Xiao-Yu Zheng (BUCM: Beijing University of Chinese Medicine)
#2Yehao Zhang (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 3
Last. Jian-Xun Liu (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 25
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Buyang Huanwu Decoction, a representative prescription in traditional Chinese medicine(TCM) for tonifying Qi and activating blood, has been proved to be effective in preventing and treating acute cerebral infarction(ACI). It consists of Astragali Radix, Angelicae Sinensis Radix, Paeoniae Radix Rubra, Pheretima, Chuanxiong Rhizoma, Carthami Flos, and Persicae Semen, possessing multiple active ingredients. The neurovascular unit is a functionally and structurally interdependent multicellular compl...
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#1Yu-Jie Wu (BUCM: Beijing University of Chinese Medicine)
#2Zhibo Wang (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 1
Last. Jian-Xun Liu (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 25
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Compound Renshen Buqi Granules have been widely used to treat chronic heart failure(CHF) due to Qi deficiency and blood stasis, but the mechanism of action remains unclear. This paper explored the pathogenesis of CHF due to Qi deficiency and blood stasis and the intervention mechanism of Compound Renshen Buqi Granules based on quantitative proteomics for uncovering the biological basis. SD rats were divided into the normal control(N) group, normal+Compound Renshen Buqi Granules(ND) group, model(...
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#1Xiaoyan Xu (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 1
#2Luo Xia (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 1
Last. Mengyao Yu (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 1
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Polysaccharide is among the main active components of Ganoderma lucidum for tumor prevention and treatment. Howe-ver, it remains unclear whether it has synergy with tumor immunotherapy. This study evaluated the effect of G. lucidum polysaccharides(GLP) on the infiltration of T lymphocytes into tumor and the underlying mechanism, in order to provide a reference for its application in tumor immunotherapy. GLP were prepared by water extraction and alcohol precipitation combined with Sevag method an...
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#1Zheng Wang (BUCM: Beijing University of Chinese Medicine)
#2Yawen Wang (BUCM: Beijing University of Chinese Medicine)
Last. Bing Xu (BUCM: Beijing University of Chinese Medicine)H-Index: 12
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The high shear wet granulation(HSWG) process of Chinese medicine has a complicated mechanism. There are many influencing factors that contribute to this process. In order to summarize the manufacturability of different kinds of materials in HSWG, this paper constructed a material library composed of 11 materials, including 4 Chinese medicine extracts and 7 pharmaceutical excipients. Each material was described by 22 physical parameters. Several binders were employed, and their density, viscosity...
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#1Yue Wang (MOE: Ministry of Education of the People's Republic of China)H-Index: 1
#2Kai-Lin Yang (MOE: Ministry of Education of the People's Republic of China)H-Index: 1
Last. Xiao Peigen (MOE: Ministry of Education of the People's Republic of China)
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Withania somnifera, also known as Indian ginseng, is an important traditional medicine in the Ayurvedic medical system of India, which has a significant effect of adaptation. Modern studies have shown that the main chemical components of W. somnifera are withanolides, which have antioxidant, anti-tumor, enhancing immunity, cardiovascular protection, neuroprotection, anti-stress, anti-stress reaction and hypoglycemic activities. Studies on human, animal, mutagenesis, genotoxicity, reproductive to...
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#2Wu-Li-Ji Ao (IMUN: Inner Mongolia University for Nationalities)H-Index: 5
Last. Xiao-Hua Bao (IMUN: Inner Mongolia University for Nationalities)H-Index: 4
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Mongolians have a long history of using prescriptions, which can be classified into four stages as follows: the germination and experience accumulation stage before the 13 th century, the theoretical formation stage from the 13 th to 16 th century, the rapid development stage from the 17 th to 20 th century, and the leaping development stage from the mid-20 th century to the present. The prescriptions from the ancient classical or representative medical books have always been used by Mongolian p...
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