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Semb AG, Rollefstad S, Ikdahl E, et al. SURF-RA collaborators. Diabetes mellitus and cardiovascular risk management in patients with rheumatoid arthritis: an …
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#1Ayşe A Küçükdeveci (Ankara University)H-Index: 20
#2Atilla Halil Elhan (Ankara University)H-Index: 46
Last. Gerold Stucki (University of Lucerne)H-Index: 106
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INTRODUCTION The importance of patient-reported outcome measures (PROMs) for rheumatoid arthritis (RA) clinical studies has been recognised for many years. The current study aims to describe the RA PROMs used over the past 20 years, and their performance metrics, to underpin appropriate tool selection. METHODS The study included a systematic search for PROMs that have been in use over the period 2000-2019, with detailed documentation of their psychometric properties, and a user-friendly presenta...
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#1Daniel Aletaha (Medical University of Vienna)H-Index: 86
#2Rene Westhovens (Katholieke Universiteit Leuven)H-Index: 64
Last. Zhaoyu YinH-Index: 4
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OBJECTIVE This analysis evaluated efficacy and safety of filgotinib, a Janus-associated kinase 1-preferential inhibitor, in methotrexate (MTX)-naive patients with rheumatoid arthritis (RA) with multiple poor prognostic factors (PPFs). METHODS This was a post hoc analysis of the phase III, randomised, double-blind, active-controlled, FINCH 3 study (clinicaltrials.gov NCT02886728). Patients received once-daily oral filgotinib 200 or 100 mg plus once-weekly oral MTX ≤20 mg (FIL200 + MTX and FIL100 ...
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#1Elisabeth Gjefsen (University of Oslo)
#2Kristina Gervin (Oslo University Hospital)H-Index: 18
Last. Are Hugo Pripp (Oslo University Hospital)H-Index: 30
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Background null Low back pain (LBP) is a leading cause of disability worldwide, but the aetiology remains poorly understood. Finding relevant biomarkers may lead to better understanding of disease mechanisms. Patients with vertebral endplate bone marrow lesions visualised on MRI as Modic changes (MCs) have been proposed as a distinct LBP phenotype, and inflammatory mediators may be involved in the development of MCs. null Objectives null To identify possible serum biomarkers for LBP in patients ...
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#1Magdalena Zasada (RMIT: RMIT University)H-Index: 4
#2Mark Yates ('KCL': King's College London)H-Index: 6
Last. Cath Taylor (RMIT: RMIT University)H-Index: 19
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Background null Evidence from a national clinical audit of early inflammatory arthritis (EIA) shows considerable variability between hospitals in performance, unexplained by controlling for case-mix. null Objective null To explore the macro-level, meso-level and micro-level barriers and facilitators to the provision of good quality EIA care. null Methods null A qualitative study within 16 purposively sampled rheumatology units across England and Wales. Quality was assessed in relation to 11 qual...
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#1Francesco UrsiniH-Index: 18
#2Jacopo CiaffiH-Index: 5
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OBJECTIVE: Postacute COVID-19 syndrome (PACS) is an emerging entity characterised by a large array of manifestations, including musculoskeletal complaints, fatigue and cognitive or sleep disturbances. Since similar symptoms are present also in patients with fibromyalgia (FM), we decided to perform a web-based cross-sectional survey aimed at investigating the prevalence and predictors of FM in patients who recovered from COVID-19. METHODS: Data were anonymously collected between 5 and 18 April 20...
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#2Christoph LadelH-Index: 16
Last. Paco M J WelsingH-Index: 30
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OBJECTIVES To describe the relations between baseline clinical characteristics of the Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) participants and their predicted probabilities for knee osteoarthritis (OA) structural (S) progression and/or pain (P) progression. METHODS Baseline clinical characteristics of the IMI-APPROACH participants were used for this study. Radiographs were evaluated according to Kellgren and Lawrence (KL p<0.001, KL p=0.028). Parti...
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#1Hieronymus T W Smeele (EUR: Erasmus University Rotterdam)H-Index: 3
#2Marco W. J. Schreurs (EUR: Erasmus University Rotterdam)H-Index: 35
Last. Radboud J E M Dolhain (EUR: Erasmus University Rotterdam)H-Index: 28
view all 5 authors...
Objectives null Guidelines advise to test for anti–Sjogren9s-syndrome-related antigen A (anti-SSA) and anti–Sjogren9s-syndrome-related antigen B (anti-SSB) antibodies in all patients with rheumatoid arthritis (RA) who wish to conceive. Our objective was to determine the prevalence and titres of anti-SSA and anti-SSB autoantibodies in patients with RA with a wish to conceive or pregnant. null Methods null Patients were derived from two large cohorts on RA and pregnancy (PARA cohort and PreCARA co...
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#1Claudia Kedor (Charité)H-Index: 4
#2Jacqueline Detert (Charité)H-Index: 17
Last. Frank Buttgereit (Charité)H-Index: 71
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Objectives null Hand osteoarthritis (OA) is a condition characterised by cartilage degradation and frequently erosive changes. Analgesics and non-steroidal anti-inflammatory drugs are used for symptomatic relief but are often poorly tolerated or contraindicated. Previous publications suggest hydroxychloroquine (HCQ) as a possible treatment for hand OA. The OA-TREAT study aimed to investigate the efficacy and safety of HCQ in patients with inflammatory and erosive hand OA (EOA). null Methods null...
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#1Nasim A. KhanH-Index: 14
#2Karina D. Torralba (LLU: Loma Linda University)H-Index: 13
Last. Fawad Aslam (Mayo Clinic)H-Index: 11
view all 3 authors...
Objectives null To analyse the amount, reporting and handling of missing data, approach to intention-to-treat (ITT) principle application and sensitivity analysis utilisation in randomised clinical trials (RCTs) of rheumatoid arthritis (RA). To assess the trend in such reporting 10 years apart (2006 and 2016). null Methods null Parallel group drug therapy RA RCTs with a clinical primary endpoint. null Results null 176 studies enrolling a median of 160 (IQR 62–339) patients were eligible. In term...
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