Advanced Science
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#1Guangtao Zan (Tongji University)H-Index: 3
#2Tong Wu (Tongji University)H-Index: 2
Last. Qingsheng Wu (Tongji University)H-Index: 34
view all 12 authors...
In flexible electronics, appropriate inlaid structures for stress dispersion to avoid excessive deformation that can break chemical bonds are lacking, which greatly hinders the fabrication of super-foldable composite materials capable of sustaining numerous times of true-folding. Here, mimicking the microstructures of both cuit cocoon possessing super-flexible property and Mimosa leaf featuring reversible scatheless folding, super-foldable C-web/FeOOH-nanocone (SFCFe) conductive nanocomposites a...
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#1Hyun-Joong Kim (SNU: Seoul National University)H-Index: 58
#2Tae Yong Yoo (SNU: Seoul National University)H-Index: 2
Last. Taeghwan Hyeon (SNU: Seoul National University)H-Index: 151
view all 6 authors...
Noble metal-based multimetallic nanoparticles (NMMNs) have attracted great attention for their multifunctional and synergistic effects, which offer numerous catalytic applications. Combined experimental and theoretical studies have enabled formulation of various design principles for tuning the electrocatalytic performance through controlling size, composition, morphology, and crystal structure of the nanoparticles. Despite significant advancements in the field, the chemical synthesis of NMMNs w...
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#1Qing Liu (BIT: Beijing Institute of Technology)H-Index: 1
#2Bo Wu (Center for Excellence in Education)
Last. Lele Li (Center for Excellence in Education)H-Index: 33
view all 5 authors...
Heterostructure nanoparticles (NPs), constructed by two single-component NPs with distinct nature and multifunctional properties, have attracted intensive interest in the past few years. Among them, heterostructures made of upconversion NPs (UCNPs) and metal-organic frameworks (MOFs) can not only integrate the advantageous characteristics (e.g., porosity, structural regularity) of MOFs with unique upconverted optical features of UCNPs, but also induce cooperative properties not observed either f...
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#1Philip Chiu-Tsun Tang (CUHK: Chinese University of Hong Kong)H-Index: 6
#2Jeff Yat-Fai Chung (CUHK: Chinese University of Hong Kong)H-Index: 6
Last. Hui-Yao Lan (CUHK: Chinese University of Hong Kong)H-Index: 34
view all 16 authors...
Cancer-associated fibroblasts (CAFs) are important in tumor microenvironment (TME) driven cancer progression. However, CAFs are heterogeneous and still largely underdefined, better understanding their origins will identify new therapeutic strategies for cancer. Here, the authors discovered a new role of macrophage-myofibroblast transition (MMT) in cancer for de novo generating protumoral CAFs by resolving the transcriptome dynamics of tumor-associated macrophages (TAM) with single-cell resolutio...
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#1Yuxia Sun (XMU: Xiamen University)H-Index: 2
#2Xiang Chen (XMU: Xiamen University)H-Index: 5
Last. Ying Chen (XMU: Xiamen University)H-Index: 18
view all 8 authors...
Depression is a mental disorder affecting more than 300 million people in the world. Abnormalities in white matter are associated with the development of depression. Here, the authors show that mice with oligodendrocyte-specific deletion of Nerve injury-induced protein 2 (Ninj2) exhibit depressive-like behaviors. Loss of Ninj2 in oligodendrocytes inhibits oligodendrocyte development and myelination, and impairs neuronal structure and activities. Ninj2 competitively inhibits TNFα/TNFR1 signaling ...
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#1Xiaodong Meng (BUCT: Beijing University of Chemical Technology)H-Index: 3
#2Xing Liu (SHU: Shanghai University)
Last. Jianxin Geng (BUCT: Beijing University of Chemical Technology)H-Index: 33
view all 13 authors...
Electrocatalysis is critical to the performance displayed by sulfur cathodes. However, the constituent electrocatalysts and the sulfur reactants have vastly different molecular sizes, which ultimately restrict electrocatalysis efficiency and hamper device performance. Herein, the authors report that aggregates of cobalt single-atom catalysts (SACs) attached to graphene via porphyrins can overcome the challenges associated with the catalyst/reactant size mismatch. Atomic-resolution transmission e...
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#1Yongqi Chen (Sun Yat-sen University)H-Index: 2
#2Junlong Huang (Sun Yat-sen University)H-Index: 10
Last. Dingcai Wu (Sun Yat-sen University)H-Index: 60
view all 10 authors...
Carbon-based nanomaterials have been regarded as promising non-noble metal catalysts for renewable energy conversion system (e.g., fuel cells and metal-air batteries). In general, graphitic skeleton and porous structure are both critical for the performances of carbon-based catalysts. However, the pursuit of high surface area while maintaining high graphitization degree remains an arduous challenge because of the trade-off relationship between these two key characteristics. Herein, a simple yet ...
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#1Dong Yang (Hebei University)H-Index: 3
#2Xiangbo Wu (Hebei University)H-Index: 1
Last. Zhenshan Wang (Hebei University)H-Index: 11
view all 5 authors...
Neuronal primary cilia are crucial for body weight maintenance. Type III adenylyl cyclase (AC3) is abundantly enriched in neuronal cilia, and mice with global AC3 ablation are obese. However, whether AC3 regulates body weight through its ciliary expression and the mechanism underlying this potential regulation are not clear. In this study, humanized AC3 knock-in mice that are resistant to high-fat diet (HFD)-induced obesity are generated, and increases in the number and length of cilia in the ve...
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#1Quinton Smith (HHMI: Howard Hughes Medical Institute)H-Index: 9
#2Jennifer L. Bays (Wyss Institute for Biologically Inspired Engineering)H-Index: 5
Last. Sangeeta N. BhatiaH-Index: 115
view all 6 authors...
Patients with Alagille syndrome carry monogenic mutations in the Notch signaling pathway and face complications such as jaundice and cholestasis. Given the presence of intrahepatic ductopenia in these patients, Notch2 receptor signaling is implicated in driving normal biliary development and downstream branching morphogenesis. As a result, in vitro model systems of liver epithelium are needed to further mechanistic insight of biliary tissue assembly. Here, primary human intrahepatic cholangiocyt...
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#1Shun YaoH-Index: 1
#2Yuetong Wang (SEU: Southeast University)H-Index: 11
Last. Yongan WangH-Index: 2
view all 7 authors...
Patches with the capacity of controllable delivering active molecules toward the wound bed to promote wound healing are expectant all along. Herein, a novel porous metal-organic framework (MOF) microneedle (MN) patch enabling photothermal-responsive nitric oxide (NO) delivery for promoting diabetic wound healing is presented. As the NO-loadable copper-benzene-1,3,5-tricarboxylate (HKUST-1) MOF is encapsulated with graphene oxide (GO), the resultant NO@HKUST-1@GO microparticles (NHGs) are imparte...
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