Biofabrication
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Papers 912
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#1Gabriella Nilsson Hall (Katholieke Universiteit Leuven)H-Index: 4
#2Iene Rutten (Katholieke Universiteit Leuven)H-Index: 4
Last. Ioannis Papantoniou (Katholieke Universiteit Leuven)H-Index: 17
view all 7 authors...
Spheroids have become essential building blocks for biofabrication of functional tissues. Spheroid formats allow high cell-densities to be efficiently engineered into tissue structures closely resembling the native tissues. In this work, we explore the assembly capacity of cartilaginous spheroids (d~150 µm) in the context of endochondral bone formation. The fusion capacity of spheroids at various degrees of differentiation was investigated indicating decreased kinetics as well as decreased remod...
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#1Shaohua Wu (Qingdao University)H-Index: 18
#2Jiao Liu (Qingdao University)
Last. Bin Duan (UNMC: University of Nebraska Medical Center)H-Index: 30
view all 6 authors...
Fiber constructed yarns are the elementary building blocks for the generation of implantable biotextiles, and there are always needs for designing and developing new types of yarns to improve the properties of biotextile implants. In the present study, we aim to develop novel nanofiber yarns by combining nanostructure that more closely mimic the extracellular matrix (ECM) fibrils of native tissues with biodegradability, strong mechanical properties and great textile processibility. A novel elect...
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#1Anna Nakamura (Saga University)H-Index: 3
#2Daiki Murata (Saga University)H-Index: 7
Last. Koichi Nakayama (Saga University)H-Index: 18
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Osteoarthritis is a leading cause of pain and joint immobility, the incidence of which is increasing worldwide. Currently, total joint replacement is the only treatment for end-stage disease. Scaffold-based tissue engineering is a promising alternative approach for joint repair but is subject to limitations such as poor cytocompatibility and degradation-associated toxicity. To overcome these limitations, a completely scaffold-free Kenzan method for bio-3D printing was used to fabricate cartilage...
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#1Elia A. Guzzi (ETH Zurich)H-Index: 4
#2Raffaele Bischof (ETH Zurich)
Last. Mark W. Tibbitt (ETH Zurich)H-Index: 25
view all 8 authors...
Recent advances in additive manufacturing (AM) technologies provide tools to fabricate biological structures with complex three-dimensional (3D) organization. Deposition-based approaches have been exploited to manufacture multimaterial constructs. Stimulus-triggered approaches have been used to fabricate scaffolds with high resolution. Both features are useful to produce biomaterials that mimic the hierarchical organization of human tissues. Recently, multitechnology biofabrication approaches ha...
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#1Park Yejin (POSTECH: Pohang University of Science and Technology)
#2Seung Taek Ji (PNU: Pusan National University)H-Index: 9
Last. Jinah Jang (POSTECH: Pohang University of Science and Technology)H-Index: 31
view all 8 authors...
Intercellular interaction is the most crucial factor in promoting cell viability and functionality in an engineered tissue system. Of the various shapes available for cell-laden constructs, spheroidal multicellular microarchitectures (SMMs) have been introduced as building blocks and injectable cell carriers with substantial cell-cell and cell-extracellular matrix (ECM) interactions. Here, we developed a precise and expeditious SMM printing method that can create a tissue-specific microenvironme...
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#1Shun Li (University of Electronic Science and Technology of China)H-Index: 15
#2Kaifu Yang (University of Electronic Science and Technology of China)
Last. Xiang Qin (University of Electronic Science and Technology of China)H-Index: 12
view all 15 authors...
Cell culture systems are indispensable in vitro tools for biomedical research. Although conventional two-dimensional (2D) cell cultures are still used for most biomedical and biological studies, the three dimensional (3D) cell culture technology attracts increasing attention from researchers, especially in cancer and stem cell research. Due to the different spatial structures, cells in 2D and 3D cultures exhibit different biochemical and biophysical phenotypes. Therefore, a new platform with bot...
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#1Seong Jin Lee (POSTECH: Pohang University of Science and Technology)H-Index: 5
#2Yoojun Nam (Catholic University of Korea)H-Index: 9
Last. Dong Sung Kim (POSTECH: Pohang University of Science and Technology)H-Index: 27
view all 6 authors...
The pellet formation has been regarded as a golden standard for in vitro chondrogenic differentiation. However, a spatially inhomogeneous chondrogenic microenvironment around a pellet resulted from the use of a traditional impermeable narrow tube, such as the conical tube, undermines the differentiation performance and therapeutic potential of differentiated cartilage pellet in defective articular cartilage treatment. To address this drawback, a perichondrium-inspired permeable nanofibrous tube ...
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#1Kyung-Seob Kim (KU: Korea University)
#2Hyung Joon Joo (KU: Korea University)H-Index: 16
Last. Tae Hoon Ahn (KU: Korea University)H-Index: 19
view all 14 authors...
A novel tissue engineering strategy using 3D bio-print technology has become a promising therapeutic method for acute myocardial infarction (AMI) in an animal model. However, the application of 3D bio-printed tissue remains limited due to poor graft survival. Therefore, it is a scientific priority to enhance graft survival by precisely adjusting the 3D environment of encapsulated cells. In this study, novel transplantable 3D cardiac mesh (cMesh) tissue with a porous mesh structure was presented ...
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#1Se-Ra Park (Gachon University)H-Index: 9
#2Soo-Rim Kim (Gachon University)H-Index: 7
Last. In-Sun Hong (Gachon University)H-Index: 11
view all 6 authors...
Thin endometrium lining or severe endometrial injury which may occur during artificial abortion can cause defective endometrial receptivity and subsequent infertility. Therefore, much effort has been devoted toward regenerating thin or damaged endometrial lining by applying multiple types of stem cells. Even though there are some positive preliminary outcomes, repairing the injured endometrium with stem cells is considerably challenging, due to the lack of an adequate microenvironment for the ad...
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#1Benjamin J. Carberry (CU: University of Colorado Boulder)H-Index: 2
#2John E. Hergert (CU: University of Colorado Boulder)H-Index: 1
Last. Kristi S. Anseth (CU: University of Colorado Boulder)H-Index: 123
view all 8 authors...
Biofabrication allows for the templating of structural features in materials on cellularly-relevant size scales, enabling the generation of tissue-like structures with controlled form and function. This is particularly relevant for growing organoids, where the application of biochemical and biomechanical stimuli can be used to guide the assembly and differentiation of stem cells and form architectures similar to the parent tissue or organ. Recently, ablative laser-scanning techniques was used to...
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Top fields of study
Biomedical engineering
Composite material
Nanotechnology
Materials science
Tissue engineering
Scaffold