Biomaterials Science
Papers 2477
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#1Haruko Takahashi (Hiroshima University)
#1Haruko TakahashiH-Index: 13
Last. Kenichi KurodaH-Index: 26
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#1Irene Anton-Sales (ICMAB: Institute of Cost and Management Accountants of Bangladesh)H-Index: 3
#2Soledad Roig-Sanchez (ICMAB: Institute of Cost and Management Accountants of Bangladesh)H-Index: 3
Last. Anna Roig (ICMAB: Institute of Cost and Management Accountants of Bangladesh)H-Index: 40
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The use of surgical meshes to reinforce damaged internal soft tissues has been instrumental for successful hernia surgery; a highly prevalent condition affecting yearly more than 20 million patients worldwide. Intraperitoneal adhesions between meshes and viscera are one of the most threatening complications, often implying reoperation or side effects such as chronic pain and bowel perforation. Despite recent advances in the optimization of mesh porous structure, incorporation of anti-adherent co...
#1Ciarstan McArdle (National University of Ireland, Galway)
#2Sunny A. Abbah (National University of Ireland, Galway)H-Index: 15
Last. Abhay Pandit (National University of Ireland, Galway)H-Index: 54
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Hypertrophic scarring (HS) is an intractable complication associated with cutaneous wound healing. Although transforming growth factor β1 (TGF-β1) has long been documented as a central regulatory cytokine in fibrogenesis and fibroplasia, there is currently no cure. Gene therapy is emerging as a powerful tool to attenuate the overexpression of TGF-β1 and its signaling activities. An effective approach may require transferring multiple genes to regulate different aspects of TGF-β1 signaling activi...
Efficacious cancer treatment largely relies on accurate imaging diagnosis and imaging-guided surgery, which can be achieved by combining different mode imaging probes on one single nanoplatform. Herein, a novel radiolabeled NIR-II nanoprobe (125I-MT NP) was developed to enable versatile single-photon emission computed tomography (SPECT) and second near-infrared (NIR-II) fluorescence dual-modal imaging against breast cancer. 125I-MT was precipitated with an amphiphilic triblock copolymer (PEO-PPO...
#1Thomas Distler (FAU: University of Erlangen-Nuremberg)H-Index: 7
#2L. Kretzschmar (FAU: University of Erlangen-Nuremberg)H-Index: 1
Last. Silvia Budday (FAU: University of Erlangen-Nuremberg)H-Index: 17
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3D-printing technologies, such as biofabrication, capitalize on the homogeneous distribution and growth of cells inside biomaterial hydrogels, ultimately aiming to allow for cell differentiation, matrix remodeling, and functional tissue analogues. However, commonly, only the mechanical properties of the bioinks or matrix materials are assessed, while the detailed influence of cells on the resulting mechanical properties of hydrogels remains insufficiently understood. Here, we investigate the pro...
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#1Manjyot Kaur Chug (UGA: University of Georgia)
#1Manjyot Kaur ChugH-Index: 4
Last. Elizabeth J. BrisboisH-Index: 14
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The current use of implantable and indwelling medical is limited due to potential microbial colonization leading to severe ailments. The aim of this work is to develop bioactive polymers that can be customized based on patient needs and help prevent bacterial infection. Potential benefits of additive manufacturing technology are integrated with the antimicrobial properties of nitric oxide (NO) to develop NO-releasing biocompatible polymer interfaces for addressing bacterial infections. Using fil...
#1Eiji YubaH-Index: 22
Last. Kenji KonoH-Index: 44
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For the establishment of advanced medicines such as cancer immunotherapy, high performance carriers that precisely deliver biologically active molecules must be developed to target organelles of the cells and to release their contents there. From the viewpoint of antigen delivery, endosomes are important target organelles because they contain immune-response-related receptors and proteins of various types. To obtain carriers for precision endosome delivery, a novel type of polyamidoamine dendron...
#1Lijun Wu (Soochow University (Suzhou))H-Index: 1
Last. David L. Kaplan (Tufts University)H-Index: 155
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The development of hydrogels that support vascularization to improve the survival of skin flaps, yet establishing homogeneous angiogenic niches without compromising the ease of use in surgical settings remains a challenge. Here, pressure-driven spreadable hydrogels were developed utilizing beta-sheet rich silk nanofiber materials. These silk nanofiber-based hydrogels exhibited excellent spreading under mild pressure to form a thin coating to cover all the regions of the skin flaps. Deferoxamine ...
#1Sueon KimH-Index: 4
Last. Tai-Gyu KimH-Index: 25
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#1Gema Dura (Newcastle University)H-Index: 3
#2Maria Crespo-Cuadrado (Newcastle University)H-Index: 1
Last. David A. Fulton (Newcastle University)H-Index: 25
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Demand continues to grow for biomimetic materials able to create well-defined environments for modulating the behaviour of living cells in culture. Here, we describe hydrogels based upon the polymeric bacterial fimbriae protein capsular antigen fragment 1 (Caf1) that presents tunable biological properties for enhanced tissue cell culture applications. We demonstrate how Caf1 hydrogels can regulate cellular functions such as spreading, proliferation and matrix deposition of human dermal fibroblas...
Top fields of study
Organic chemistry
In vivo
Drug delivery