Journal of the American Heart Association
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4.61
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5368
Papers 6499
1 page of 650 pages (6,499 results)
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#1Kyeong Ho Yun (Wonkwang University)H-Index: 17
#2Seung Yul Lee (Wonkwang University)H-Index: 11
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Background This study sought to investigate the safety of 3‐month dual antiplatelet therapy (DAPT) in patients receiving ultrathin sirolimus‐eluting stents with biodegradable polymer (Orsiro). Meth...
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#1Xuejing Sun (South University)
#2Mengli Zhou (South University)
Last. Jingjing Cai (South University)
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Background ADRB1 (adrenergic receptor beta 1) responds to neuroendocrine stimulations, which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) is an essential regu...
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Background Contrast-associated acute kidney injury (CA-AKI) is associated with substantial morbidity and may be prevented by using less contrast during percutaneous coronary intervention (PCI). However, tools for determining safe contrast volumes are limited. We developed risk models to tailor safe contrast volume limits during PCI. Methods and Results Using data from all PCIs performed at 18 hospitals from January 2015 to March 2018, we developed logistic regression models for predicting CA-AKI...
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#1Leonardo Maciel (UFRJ: Federal University of Rio de Janeiro)H-Index: 5
#2Dahienne Ferreira de Oliveira (UFRJ: Federal University of Rio de Janeiro)H-Index: 3
Last. Debora Foguel (UFRJ: Federal University of Rio de Janeiro)H-Index: 36
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Background CDNF (cerebral dopamine neurotrophic factor) belongs to a new family of neurotrophic factors that exert systemic beneficial effects beyond the brain. Little is known about the role of CDNF in the cardiac context. Herein we investigated the effects of CDNF under endoplasmic reticulum-stress conditions using cardiomyocytes (humans and mice) and isolated rat hearts, as well as in rats subjected to ischemia/reperfusion (I/R). Methods and Results We showed that CDNF is secreted by cardiomy...
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#2Rohit M. Oemrawsingh (Albert Schweitzer Hospital)
Last. Eric BoersmaH-Index: 117
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Background Detailed insights in temporal evolution of high-sensitivity cardiac troponin following acute coronary syndrome (ACS) are currently missing. We aimed to describe and compare the post-ACS kinetics of high-sensitivity cardiac troponin I (hs-cTnI) and high-sensitivity cardiac troponin T (hs-cTnT), and to determine their intra- and interindividual variation in clinically stable patients. Methods and Results We determined hs-cTnI (Abbott) and hs-cTnT (Roche) in 1507 repeated blood samples, ...
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#1Oktay Tutarel (LMU: Ludwig Maximilian University of Munich)
#2Karishma P. Ramlakhan (Erasmus University Medical Center)H-Index: 1
Last. Jolien W. Roos-Hesselink (Erasmus University Medical Center)H-Index: 18
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Background In the past 3 decades, the arterial switch procedure has replaced the atrial switch procedure as treatment of choice for transposition of the great arteries. Although survival is superio...
1 CitationsSource
#1Hilmi Alnsasra (Mayo Clinic)H-Index: 3
#2Rabea Asleh (Mayo Clinic)H-Index: 17
Last. Sudhir S. Kushwaha (Mayo Clinic)H-Index: 39
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Background Myocardial fibrosis is an important contributor for development of diastolic dysfunction. We investigated the impact of sirolimus as primary immunosuppression on diastolic dysfunction and fibrosis progression among heart transplantation recipients. Methods and Results In 100 heart transplantation recipients who were either treated with a calcineurin inhibitor (CNI) (n=51) or converted from CNI to sirolimus (n=49), diastolic function parameters were assessed using serial echocardiogram...
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Background Large‐scale studies describing modern populations using an implantable cardioverter‐defibrillator (ICD) are lacking. We aimed to analyze the incidence of arrhythmia, device interventions...
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#1Matthew J. Singleton (Wake Forest University)H-Index: 3
#2Charles A. German (Wake Forest University)H-Index: 2
Last. Joseph Yeboah (Wake Forest University)H-Index: 26
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Background Higher body mass index (BMI) is associated with increased risk of incident atrial fibrillation (AF), but it is not known whether this relationship varies by race/ethnicity. Methods and Results Eligible participants (6739) from MESA (Multi-Ethnic Study of Atherosclerosis) were surveilled for incident AF using MESA hospital surveillance, scheduled MESA study ECG, and Medicare claims data. After a median 13.8 years of follow-up, 970 participants (14.4%) had incident AF. With BMI modeled ...
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#1Kevin R. Bainey (U of A: University of Alberta)H-Index: 16
#2Wendimagegn Alemayehu (U of A: University of Alberta)H-Index: 6
Last. Ajay J. Kirtane (CUMC: Columbia University Medical Center)H-Index: 64
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Background The ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial failed to show a reduction in hard clinical end points with an early invasive strategy in stable ischemic heart disease (SIHD). However, the influence of left main disease and high-risk coronary anatomy was left unaddressed. In a large angiographic disease-based registry, we examined the modulating effect of revascularization on long-term outcomes in anatomically high-risk...
1 CitationsSource
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