Papers 985
1 page of 99 pages (985 results)
#1Ya Liu (Chalmers University of Technology)H-Index: 4
#2Changhong Zhao (Xinxiang Medical University)H-Index: 5
Last. Johan Liu (SHU: Shanghai University)H-Index: 54
view all 0 authors...
#1Satoko Hayashi (Wakayama University)H-Index: 25
#2Taro Nishide (Wakayama University)H-Index: 2
Last. Waro Nakanishi (Wakayama University)H-Index: 25
view all 0 authors...
#1Patricia Korn (RWTH Aachen University)
#2Arno Classen (RWTH Aachen University)H-Index: 3
Last. Giulia Rossetti (Forschungszentrum Jülich)H-Index: 19
view all 0 authors...
Intracellular ADP-ribosyltransferases catalyze mono- and poly-ADP-ribosylation and affect a broad range of biological processes. The mono-ADP-ribosyltransferase PARP10 is involved in signaling and DNA repair. Previous studies identified OUL35 as a selective, cell permeable inhibitor of PARP10. We have further explored the chemical space of OUL35 by synthesizing and investigating structurally related analogs. Key synthetic steps were metal-catalyzed cross-couplings and functional group modificati...
#1Aritomo Yamaguchi (AIST: National Institute of Advanced Industrial Science and Technology)H-Index: 24
#2Yuka Murakami (AIST: National Institute of Advanced Industrial Science and Technology)
Last. Kazuaki WakitaH-Index: 1
view all 0 authors...
Hydrogenolysis of the furan rings of furfural and furfuryl alcohol, which can be obtained from biomass, has attracted attention as a method for obtaining valuable chemicals such as 1,2-pentanediol. In this study, we examined the hydrogenolysis of furfuryl alcohol to 1,2-pentanediol over Pd/C, Pt/C, Rh/C, and various supported Ru catalysts in several solvents. In particular, we investigated the effects of combinations of solvents and supports on the reaction outcome. Of all the tested combination...
#1Takashi Nomura (Kyoto University)H-Index: 2
#2Eiji Minami (Kyoto University)H-Index: 13
Last. Haruo Kawamoto (Kyoto University)H-Index: 37
view all 3 authors...
Hydrogen bond donor solvents such as aromatic solvents inhibit the secondary degradation of cellulose-derived primary pyrolysis products. In a previous study, we found that the formation of solid carbonized products was completely inhibited during cellulose pyrolysis in aromatic solvents, with 5-hydroxymethylfurfural (5-HMF) recovered in certain yields instead. This indicated that 5-HMF is an intermediate in cellulose carbonization. To confirm this hypothesis, the thermal reactivity of 5-HMF was...
The electrochemical conversion of carbon dioxide (CO2 ) to carbon monoxide (CO) is a favorable approach to reduce CO2 emission while converting excess sustainable energy to important chemical feedstocks. At high current density (>100 mA cm-2 ), low energy efficiency (EE) and unaffordable cell cost limit the industrial application of conventional CO2 electrolyzers. Thus, a crucial and urgent task is to design a new type of CO2 electrolyzer that can work efficiently at high current density. Here w...
#2Stanislav Kafka (Tomas Bata University in Zlín)H-Index: 10
3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position is the methyl group. In the methanol solution, the reaction proceeds by an addition mechanism to form 2-oxo-1a,2,3,7b-tetrahydrooxireno[2,3-c]quinoline-7b-carbonitriles, from which 4-hydroxy-3-methoxy-2-oxo-1,2,3,4-tetrahydroquinoline-4-carbonit...
Two novel alkaloids compounds together with fifteen know metabolites were identified from Aspergillus ochraceus. The stereochemistry features of the new molecules were determined via HRESIMS, NMR, ECD, and XRD analyses. Amongst these, compounds two compounds exhibited potential efficacy as anti-Parkinson's disease with the EC50 values of 2.30 and 2.45 μM, respectively. ADMET prediction showed that these compounds owned favorable drug-like characteristics and safe toxicity scores towards CNS drug...
Top fields of study
Organic chemistry
Inorganic chemistry
Materials science
Chemical engineering