Last. Zhi Chen(ZJU: Zhejiang University)H-Index: 33
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Abstract null null Background null Liver cirrhosis is associated with immune deficiency, which causes these patients to be susceptible to various infections, including cryptococcus infection. Mortality in cirrhotic patients with cryptococcosis has increased. The present study was to explore the risk factors of mortality and the predictive ability of different prognostic models. null null null Methods null Forty-seven cirrhotic patients with cryptococcosis at a tertiary care hospital were include...
#1Paschalis Gavriilidis(University Hospitals Birmingham NHS Foundation Trust)H-Index: 11
#2Keith J. Roberts(University Hospitals Birmingham NHS Foundation Trust)H-Index: 21
Last. Robert P. Sutcliffe(University Hospitals Birmingham NHS Foundation Trust)H-Index: 24
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Abstract null null Background null Gold standard for colorectal liver metastases (CRLM) remains hepatic resection (HR). However, patients with severe comorbidities, unresectable or deep-situated resectable CRLM are candidates for ablation. The aim of the study was to compare recurrence rate and survival benefit of the microwave ablation (MWA), radiofrequency ablation (RFA) and HR by conducting the first network meta-analysis. null null null Data sources null Systematic search of the literature w...
#1Zhong-Hua Wang(Fudan University Shanghai Medical College)
#2Kenneth I. Zheng(First Affiliated Hospital of Wenzhou Medical University)H-Index: 18
Last. Jian Wu(Fudan University Shanghai Medical College)H-Index: 105
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Abstract null null Background null Nonalcoholic fatty liver disease (NAFLD) is one of the main liver diseases, and its pathologic profile includes nonalcoholic fatty liver (NAFL) and nonalcoholic steatohepatitis (NASH). However, there is no reliable non-invasive parameter in distinguishing NASH from NAFL in clinical practice. The present study was to find a non-invasive way to differentiate these two categories of NAFLD via lipidomic analysis. null null null Methods null Lipidomic analysis was u...
BACKGROUND This study aimed to assess the association between metabolic syndrome (MetS) and severity of non-alcoholic fatty liver disease (NAFLD), and to discuss the pathological relevance of the diagnostic criteria in metabolic (dysfunction) associated fatty liver disease (MAFLD). METHODS This was a multicenter, cross-sectional study. Patients with NAFLD confirmed by liver biopsy were enrolled between July 2016 and December 2018 from 14 centers across the mainland of China. Anthropometric and m...
Last. Xiao Xu(ZJU: Zhejiang University)H-Index: 20
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Background null Non-alcoholic fatty liver disease and its advanced stage, nonalcoholic steatohepatitis (NASH), are the major cause of hepatocellular carcinoma (HCC) and other end-stage liver disease. However, the potential mechanism and therapeutic strategies have not been clarified. This study aimed to identify potential roles of miRNA/mRNA axis in the pathogenesis and drug combinations in the treatment of NASH. null Methods null Microarray GSE59045 and GSE48452 were downloaded from the Gene Ex...