Hematological Oncology
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#1Stefania Benatti (University of Modena and Reggio Emilia)H-Index: 6
#2Claudio Giacinto Atene (University of Modena and Reggio Emilia)H-Index: 3
Last. Leonardo Potenza (University of Modena and Reggio Emilia)H-Index: 27
view all 17 authors...
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#1Hanae Ida (Juntendo University)H-Index: 1
#2Yoshihiro InamotoH-Index: 19
Last. Ayumu ItoH-Index: 9
view all 13 authors...
This study characterized the outcomes of patients who underwent hematopoietic cell transplantation (HCT) for transformed follicular lymphoma (tFL), and clarified the association of low-dose anti-thymocyte globulin use with outcomes after allogeneic HCT. The retrospective study cohort included 74 consecutive patients who underwent autologous (n = 23) or allogeneic (n = 51) HCT at our center from 2000 to 2017. Compared with the allogeneic HCT group, the autologous HCT group underwent fewer systemi...
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#1Josep-Maria Ribera (Autonomous University of Barcelona)H-Index: 56
#2Mireia Morgades (Autonomous University of Barcelona)H-Index: 16
Last. José González-CamposH-Index: 12
view all 38 authors...
Despite high complete remission (CR) rates with frontline therapy, relapses are frequent in adults with T-cell acute lymphoblastic leukemia (T-ALL) with limited salvage options. We analyzed the outcomes and prognostic factors for CR to salvage therapy and overall survival (OS) of patients with R/R T-ALL included in two prospective measurable residual disease-oriented trials. Seventy-five patients (70 relapsed, 5 refractory) were identified. Relapses occurred in bone marrow, isolated or combined ...
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#1Michela Ansuinelli (Sapienza University of Rome)H-Index: 4
#2Irene Della Starza (Sapienza University of Rome)H-Index: 12
Last. Anna Guarini (Sapienza University of Rome)H-Index: 55
view all 12 authors...
In Ph+ acute lymphoblastic leukaemia (Ph+ ALL), minimal residual disease (MRD) is the most relevant prognostic factor. Currently, its evaluation is based on quantitative real-time polymerase chain reaction (Q-RT-PCR). Digital droplet PCR (ddPCR) was successfully applied to several haematological malignancies. We analyzed 98 samples from 40 Ph+ ALL cases, the majority enrolled in the GIMEMA LAL2116 trial: 10 diagnostic samples and 88 follow-up samples, mostly focusing on positive non-quantifiable...
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#1Montserrat Mesegue (University of Barcelona)H-Index: 1
#2Anna Alonso-Saladrigues (University of Barcelona)H-Index: 3
view all 12 authors...
Asparaginase (ASP) is an essential component for the acute lymphoblastic leukemia (ALL) treatment, but toxicities, such as allergy, frequently limit its use. Although the potentially lower PEG-ASP formulation immunogenicity, few studies with conflicting results have compared the allergy incidence between Escherichia coli-ASP and PEG-ASP in the same protocol. We aimed at comparing the allergy incidence in children receiving native E. coli-ASP versus PEG-ASP within the same clinical protocol (Span...
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#1Barbora Weinbergerova (Masaryk University)H-Index: 11
#2Jiri Mayer (Masaryk University)H-Index: 49
Last. Petr Husa (Masaryk University)H-Index: 13
view all 13 authors...
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#1Huijun Huang (Peking Union Medical College)H-Index: 2
#2J Y Wu (Peking Union Medical College)
Last. Qi Sun (Peking Union Medical College)H-Index: 2
view all 16 authors...
In recent years, genome-based classifications for hematological neoplasms have been proposed successively and proved to be more accurate than histologic classifications. However, some previous studies have reported the racial differences of genetic landscape in persons with hematological neoplasms including myelodysplastic syndromes (MDS), which may cause a genomic classification based on a particular ethnic group does not operate in other races. To determine whether race plays an important role...
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Introduction: COVID-19 is thought to be more frequent and severe in patients with cancer. Lymphoma patients may be especially vulnerable, due to the immunodeficiency and immune dysregulation caused by the lymphoma itself and the antitumor treatments. This study describes the characteristics and outcomes of lymphoma patients after developing COVID-19. Methods: This is a retrospective multicentre study carried out in the hospitals of the GELTAMO group, which included patients with a histological d...
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#1Christopher D'Angelo (UNMC: University of Nebraska Medical Center)H-Index: 3
#2Walter Hanel (OSU: Ohio State University)H-Index: 1
Last. Kevin A. David (RU: Rutgers University)H-Index: 12
view all 22 authors...
Diffuse large B-cell lymphoma featuring overexpression of MYC and B-Cell Lymphoma 2 (double expressor lymphoma, DEL) is associated with poor outcomes. Existing evidence suggesting improved outcomes for DEL with the use of more intensive regimens than R-CHOP is restricted to younger patients and based on limited evidence from low patient numbers. We retrospectively evaluated the impact of intensive frontline regimens versus R-CHOP in a multicenter analysis across 7 academic medical centers in the...
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