Cancer Nanotechnology
Papers 123
1 page of 13 pages (123 results)
#1Elham Poonaki (Tehran University of Medical Sciences)
#2Fatemeh Ariakia (MUMS: Mashhad University of Medical Sciences)H-Index: 3
Last. Ali GorjiH-Index: 33
view all 9 authors...
Despite advances in glioblastoma (GBM) treatments, current approaches have failed to improve the overall survival of patients. The oncogene BMI-1, a core member of the polycomb group proteins, is a potential novel therapeutic target for GBM. To enhance the efficacy and reduce the toxicity, PTC209, a BMI-1 inhibitor, was loaded into a PLGA–PEG nanoparticle conjugated with CD133 antibody (Nano-PTC209) and its effect on the behavior of human GBM stem-like cells (GSCs) and the human glioblastoma cel...
#1Monika Ruzycka-Ayoush (Medical University of Warsaw)H-Index: 1
#2Patrycja Kowalik (University of Warsaw)H-Index: 3
Last. Ireneusz P. Grudzinski (Medical University of Warsaw)H-Index: 13
view all 8 authors...
#1Zohre Zibaei (University of Tabriz)H-Index: 1
#2Esmaeil Babaei (University of Tabriz)H-Index: 12
Last. Hewa Jalal Azeez (University of Tabriz)H-Index: 2
view all 5 authors...
Here, we examined the tumoricidal effect of Gemini surfactant nanoparticles enriched with curcumin on 3D spheroid HT-29 cells. The delivery of curcumin and other phytocompounds to the tumor niche is an important challenge. Spheroid HT-29 cells were generated by using a conventional hanging drop method and exposed to different concentrations of Gemini-curcumin nanoparticles. The changes in spheroid integrity and cell viability were evaluated by measuring the spheroid diameter and LDH release, res...
1 CitationsSource
In this label-free bioassay, an electrochemiluminescence (ECL) immunosensor was developed for the quantification of breast cancer using HER-2 protein as a metastatic biomarker. For this purpose, the ECL emitter, [Ru(bpy)3]2+, was embedded into biocompatible chitosan (CS) polymer. The prepared bio-composite offered high ECL reading due to the depletion of human epidermal growth factor receptor 2 (HER-2) protein. Reduced graphene oxide (rGO) was used as substrate to increase signal stability and a...
#1Anand Bhardwaj (Charotar University of Science and Technology)H-Index: 2
#2Neeraj Jain (Charotar University of Science and Technology)H-Index: 10
Last. Kinnari Parekh (Charotar University of Science and Technology)H-Index: 15
view all 3 authors...
Magnetic fluid hyperthermia (MFH) is a successful nanotechnology application in recent decade where a biocompatible magnetic fluid is used to kill cancer cells in a controlled heating using AC magnetic field. In the present study, two ferrite-based magnetic fluids, with and without surfactant coating, were synthesized to study the effect of the outer layer of magnetic nanoparticles on cervical cancer cells. The magnetic fluid without surfactant coating (MFWI) was made stable by providing negativ...
#1Monika Ruzycka-Ayoush (Medical University of Warsaw)H-Index: 1
#2Patrycja Kowalik (University of Warsaw)H-Index: 3
Last. Ireneusz P. Grudzinski (Medical University of Warsaw)H-Index: 13
view all 8 authors...
Lung cancer is one of the most frequently diagnosed cancers all over the world and is also one of the leading causes of cancer-related mortality. The main treatment option for small cell lung cancer, conventional chemotherapy, is characterized by a lack of specificity, resulting in severe adverse effects. Therefore, this study aimed at developing a new targeted drug delivery (TDD) system based on Ag–In–Zn–S quantum dots (QDs). For this purpose, the QD nanocrystals were modified with 11-mercaptou...
2 CitationsSource
#1Ana Luísa G. Silva (UnB: University of Brasília)H-Index: 1
#2Natália V. Carvalho (UnB: University of Brasília)
Last. Sônia Nair Báo (UnB: University of Brasília)H-Index: 41
view all 7 authors...
Cancer constitutes group of diseases responsible for the second largest cause of global death, and it is currently considered one of the main public health concerns nowadays. Early diagnosis associated with the best choice of therapeutic strategy, is essential to achieve success in cancer treatment. In women, breast cancer is the second most common type, whereas ovarian cancer has the highest lethality when compared to other neoplasms of the female genital system. The present work, therefore, pr...
#1Malwina Sosnowska (Warsaw University of Life Sciences)H-Index: 5
#2Marta Kutwin (Warsaw University of Life Sciences)H-Index: 15
Last. Ewa Sawosz (Warsaw University of Life Sciences)H-Index: 25
view all 11 authors...
The extracellular matrix (ECM) is a mosaic of various structural and functional proteins that cooperate with the cell, regulate adhesion, and consequently manage its further fate. Liver destruction is accompanied by a disruption of the physicochemical properties of the ECM which deregulates the cell–ECM interaction and can lead to uncontrolled proliferation and neoplastic transformation of cells. Therefore, it can be assumed that ECM modification and restoration of its characteristics for health...
#1Jossana Damasco (SUNY: State University of New York System)H-Index: 9
#2Tymish Y. Ohulchanskyy (SUNY: State University of New York System)H-Index: 48
Last. Paras N. Prasad (SUNY: State University of New York System)H-Index: 129
view all 13 authors...
Background In this study, we report on the synthesis, imaging, and radiosensitizing properties of ultrasmall β-NaGdF4:Yb50% nanoparticles as a multifunctional theranostic platform. The synthesized nanoparticles act as potent bimodal contrast agents with superior imaging properties compared to existing agents used for magnetic resonance imaging (MRI) and computed tomography (CT). Clonogenic assays demonstrated that these nanoparticles can act as effective radiosensitizers, provided that the nanop...
#1Md. Nazir Hossen (University of Oklahoma Health Sciences Center)H-Index: 9
#1Nazir Hossen (University of Oklahoma Health Sciences Center)H-Index: 5
Last. Priyabrata Mukherjee (University of Oklahoma Health Sciences Center)H-Index: 55
view all 7 authors...
Background Ovarian cancer is one of the deadliest gynecological malignancies. While the overall survival of ovarian cancer patients has slightly improved in recent years in the developed world, it remains clinically challenging due to its frequent late diagnosis and the lack of reliable diagnostic and/or prognostic markers. The aim of this study was to identify potential new molecular target proteins (NMTPs) responsible for the poor outcomes. When nanoparticles (NP) are exposed to biological flu...
1 CitationsSource
Top fields of study
Biomedical engineering
Materials science
Drug delivery
Radiation therapy
Cancer cell