Physics in Medicine and Biology
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#1Yingtao Fang (Fudan University)H-Index: 1
#2Jiazhou Wang (Fudan University)H-Index: 14
Last. Weigang Hu (Fudan University)H-Index: 16
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To investigate the impact of training sample size on the performance of deep learning-based organ auto-segmentation for head-and-neck (HNC) cancer patients, a total of 1,160 patients with head-and-neck cancer who received radiotherapy were enrolled in this study. Patient planning CT images and regions of interest (ROIs) delineation, including the brainstem, spinal cord, eyes, lenses, optic nerves, temporal lobes, parotids, larynx and body, were collected. An evaluation dataset with 200 patients ...
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#1Julie Lascaud (LMU: Ludwig Maximilian University of Munich)H-Index: 3
#2Pratik Dash (LMU: Ludwig Maximilian University of Munich)H-Index: 1
Last. Katia Parodi (LMU: Ludwig Maximilian University of Munich)H-Index: 56
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The sharp spatial and temporal dose gradients of pulsed ion beams result in an acoustic emission (ionoacoustics), which can be used to reconstruct the dose distribution from measurements at different positions. The accuracy of range verification from ionoacoustic images measured with an ultrasound linear array configuration is investigated both theoretically and experimentally for monoenergetic proton beams at energies relevant for pre-clinical studies (20 and 22 MeV). The influence of the linea...
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#1Ahmed M Elamir (U of T: University of Toronto)
#2T Stanescu (U of T: University of Toronto)H-Index: 12
Last. Rebecca Wong (U of T: University of Toronto)H-Index: 60
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Dose painting of hypoxic tumour sub-volumes using positron-emission tomography (PET) has been shown to improve tumour control in silico in several sites, predominantly head and neck and lung cancers. Pancreatic cancer presents a more stringent challenge, given its proximity to critical gastro-intestinal (GI) organs-at-risk (OARs), anatomic motion, and impediments to reliable PET hypoxia quantification. A radiobiological model was developed to estimate clonagen survival fraction (SF), using 18F-f...
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#1Seung Eun Lee (SNU: Seoul National University)H-Index: 31
#2Jae Sung Lee (SNU: Seoul National University)H-Index: 52
Inter-crystal scattering (ICS) is a type of Compton scattering of photons from one crystal to adjacent crystals and causes inaccurate assignment of the annihilation photon interaction position in positron emission tomography (PET). Because ICS frequently occurs in highly light-shared PET detectors, its recovery is crucial for the spatial resolution improvement. In this study, we propose two different convolutional neural networks (CNNs) for ICS recovery, exploiting the good pattern recognition a...
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#1S. Colombi (University of Trento)H-Index: 3
#2M. RovitusoH-Index: 8
Last. Chiara La Tessa (University of Trento)H-Index: 5
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Carbon therapy is a promising treatment option for cancer. The physical and biological properties of carbon ions can theoretically allow for the delivery of curative doses to the tumor, while simultaneously limiting risks of toxicity to adjacent healthy structures. The treatment effectiveness can be further improved by decreasing the uncertainties stemming from several sources, including the modeling of tissue heterogeneity. Current treatment plans employ density-based conversion methods to tran...
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#1Kazuki Wakabayashi (Kindai University)H-Index: 1
#2Hajime Monzen (Kindai University)H-Index: 13
Last. Yasumasa Nishimura (Kindai University)H-Index: 25
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We have developed soft rubber (SR) bolus that can be shaped in real time by heating flexibly and repeatedly. This study investigated whether the SR bolus could be used as an ideal bolus, such as not changing of the beam characteristics and homogeneity through the bolus and high plasticity to adhere a patient in addition to real-time shapeable and reusability, in electron radiotherapy. Percentage depth doses (PDDs) and lateral dose profiles (LDPs) were obtained for 4, 6, and 9 MeV electron beams ...
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#1Sodai TanakaH-Index: 1
#2Naoki Miyamoto (Hokkaido University)H-Index: 13
Last. Taeko Matsuura (Hokkaido University)H-Index: 17
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Increasing numbers of proton imaging research studies are being conducted for accurate proton range determination in proton therapy treatment planning. However, there is no proton imaging system that deals with motion artifacts. In this study, a gated proton imaging system was developed and the first experimental results of proton radiography were obtained for a moving object without motion artifacts. A motion management system using dual x-ray fluoroscopy for detecting a spherical gold fiducial...
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#1Wencheng Shao (NUAA: Nanjing University of Aeronautics and Astronautics)
#2Yunhe Xie (Harvard University)H-Index: 4
Last. Hsiao-Ming LuH-Index: 31
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This study aims to develop a method for verifying site specific and/or beam path specific proton beam range, which could reduce range uncertainty margins and the associated treatment complications. It investigates the range uncertainties from both CT HU to relative stopping power (RSP) conversion and patient positioning errors for prostate treatment using pelvic-like biological phantoms. Three 25×14×12 cm3 phantoms, made of fresh animal tissues mimicking the pelvic anatomies of prostate patients...
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#1Aiping YaoH-Index: 4
#2Manuel MurbachH-Index: 15
Last. Niels KusterH-Index: 73
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PURPOSE To characterize and quantify the induced radiofrequency (RF) E-fields and B1+rms fields in patients undergoing magnetic resonance (MR) examinations; to provide guidance on aspects of RF heating risks for patients with and without implants; and to discuss some strengths and limitations of safety assessments in current ISO, IEC, and ASTM standards to determine the RF heating risks for patients with and without implants. METHODS Induced E-fields and B1+rms fields during 1.5T and 3T MR exami...
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#1Nicolaus Kratochwil (CERN)H-Index: 19
#2Stefan Gundacker (CERN)H-Index: 113
Last. Etiennette Auffray (CERN)H-Index: 95
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Time of flight positron emission tomography (TOF-PET) can strongly benefit from a very accurate time estimator given by Cherenkov radiation, which is produced upon a 511 keV positron-electron annihilation gamma interaction in heavy inorganic scintillators. While time resolution in the order of 30 ps FWHM has been reported using MCP-PMTs and black painted Cherenkov radiators, such solutions have several disadvantages, like high cost and low detection efficiency of nowadays available MCP-PMTs. On ...
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