American Journal of Physiology-renal Physiology
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#1Ali Sassi (University of Geneva)H-Index: 4
#2Yubao Wang (University of Geneva)H-Index: 1
Last. Eric Féraille (University of Geneva)H-Index: 42
view all 9 authors...
Fine tuning of Na+reabsorption takes place along the aldosterone-sensitive distal nephron (ASDN) which includes the collecting duct (CD) where it is mainly regulated by aldosterone. In the CD,Na+ r...
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#1Autumn N. Harris (UF: University of Florida)H-Index: 7
#2Rebeca Castro (UF: University of Florida)
Last. I. David Weiner (VA: United States Department of Veterans Affairs)H-Index: 30
view all 5 authors...
Background: There are sex differences in renal ammonia metabolism and structure, many of which are mediated by testosterone. This study's goal was to determine the role of renal expression of testo...
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#1Alejandro R. Chade (UMMC: University of Mississippi Medical Center)H-Index: 43
#2Jason E. Engel (UMMC: University of Mississippi Medical Center)H-Index: 5
Last. Gene L. Bidwell (UMMC: University of Mississippi Medical Center)H-Index: 22
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Patients with chronic kidney disease (CKD) have a high cardiovascular mortality. CKD and heart failure (HF) coexist in up to 50% of patients and both associates with inflammation. We aim to define ...
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#1Steven Menez (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 4
#2Chirag R. Parikh (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 95
Since the start of the COVID-19 pandemic, several manifestations of kidney involvement associated with infection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus have been described, including proteinuria, hematuria, and acute kidney injury. A growing body of literature has explored the risk factors and pathogenesis of COVID-19-associated acute kidney injury (AKI), including direct and indirect mechanisms, as well as early postdischarge outcomes that may result from vari...
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#1Yuika Osada (Kyoto University)
#2Shunsaku Nakagawa (Kyoto University)H-Index: 11
Last. Kazuo Matsubara (Kyoto University)H-Index: 41
view all 10 authors...
Recent studies have revealed the impact of antibiotic-induced microbiome depletion (AIMD) on host glucose homeostasis. The kidney has a critical role in systemic glucose homeostasis; however, infor...
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#1Robert L. Myette (Ottawa Hospital Research Institute)H-Index: 3
#2Dylan Burger (Ottawa Hospital Research Institute)H-Index: 29
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#2Volkan Yazar (Bilkent University)H-Index: 1
Last. Eda Çiftci Dede (Hacettepe University)H-Index: 2
view all 14 authors...
Since previous research suggests a role of a circulating factor in the pathogenesis of steroid-sensitive nephrotic syndrome (SSNS), we speculated that circulating plasma extracellular vesicles (EVs) are a candidate source of such a soluble mediator. Here, we aimed to characterize and try to delineate the effects of these EVs in vitro. Plasma EVs from 20 children with SSNS in relapse and remission, 10 healthy controls and 6 disease controls were obtained by serial ultracentrifugation. Characteriz...
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#1Zhilin Luan (Dalian Medical University)H-Index: 3
#2Wenhua Ming (Dalian Medical University)H-Index: 3
Last. Xiao-Yan Zhang (ECNU: East China Normal University)
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The ligand-activated nuclear receptor, farnesoid X receptor (FXR), plays a pivotal role in regulating renal function. Activation of FXR by its specific agonists exerts renoprotective action in anim...
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#1Yushi Uchida (Kyushu University)H-Index: 1
#2Kumiko Torisu (Kyushu University)H-Index: 13
Last. Takanari Kitazono (Kyushu University)H-Index: 64
view all 6 authors...
Albumin transport in proximal tubule epithelial cells (PTECs) is important to control proteinuria. The neonatal Fc receptor (FcRn), a receptor for albumin transcytosis, is partially colocalized wit...
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#1Jana Löwen (DKFZ: German Cancer Research Center)H-Index: 2
#2Elisabeth Gröne (DKFZ: German Cancer Research Center)H-Index: 28
Last. Wilhelm Kriz (Heidelberg University)H-Index: 81
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Based on analysis of 819 human biopsies, essential derangement in diabetic nephropathy consists of accumulation of worn-out glomerular basement membrane in the mesangium that may advance to global ...
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