Ocular Immunology and Inflammation
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#1Ranju Kharel Sitaula (TU: Tribhuvan University)H-Index: 4
#2Anadi KhatriH-Index: 5
Last. Madan P. Upadhyay (TU: Tribhuvan University)H-Index: 9
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Introduction: Classification are essential part of scientific methodology and has important role in medical reporting system. Even after having 46 years long history, Seasonal Hyperacute Panuveitis (SHAPU), the blinding diseases reported mainly from Nepal lacks a standard classification system. Thus, we aim to contribute in the ophthalmic nosology by purposing a classification system for SHAPU.Methodology: The classification is suggested on the background of prolonged experience of this entity b...
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#1Andrew R. Carey (Johns Hopkins University)H-Index: 2
#2J. Fernando Arevalo (Johns Hopkins University)H-Index: 49
Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is a rare disease marked by CNS demyelination with a predilection for the optic nerve and spinal cord often resulting in severe vision loss. We aimed to characterize uveitis occurring in the setting of NMOSD.Methods: Retrospective chart reviewResults: Of 572 NMOSD patients, 1% were found to have uveitis with a relative risk of 6.2 (95% confidence interval 3-14, p < .001) compared to the general population. The mean age of uveitis onset w...
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#1Lucy I. Mudie (University of Colorado Denver)H-Index: 7
Last. Alan G. Palestine (University of Colorado Denver)H-Index: 57
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Background: COVID-19 vaccination has been accompanied by reports of inflammatory events. This report details a case of panuveitis following vaccination for COVID-19 Case.Description: A 43 year old female developed panuveitis with decreased vision three days after her second dose of Pfizer-Biontech mRNA vaccine. The choroid was significantly thickened and there was anterior chamber and vitreous inflammation. Shortly after onset of ocular symptoms she was also found have an asymptomatic COVID-19 i...
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#1Naresh Babu Kannan (Aravind Eye Hospital)H-Index: 5
#2Piyush Kohli (Aravind Eye Hospital)H-Index: 5
Last. Kim Ramasamy (Aravind Eye Hospital)H-Index: 19
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Aim: To report the clinical presentation and management outcomes of an outbreak of culture-proven post-operative endophthalmitis (POE) secondary to Ochrobactrum anthropi.Methods: This study was conducted at a tertiary-care eye hospital in South India.Results: Fifty-five patients underwent cataract surgery by six surgeons on three consecutive days in the same surgical facility in September 2020. Four patients developed POE after a mean interval of 12.0 ± 4.8 days and underwent immediate vitreous ...
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#1Kyosuke Seki (National Defense Medical College)
#2Kozo Harimoto (National Defense Medical College)H-Index: 5
Last. Masaru Takeuchi (National Defense Medical College)H-Index: 26
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Purpose: To report a case of cytomegalovirus retinitis (CMVR) with hypopyon and intense ocular inflammation.Case report: An 81-year-old female was referred to our hospital with a suspicion of postoperative endophthalmitis in the left eye. She had been treated with etoposide and prednisolone for non-Hodgkin's lymphoma. Examination revealed mutton-fat keratic precipitates and numerous infiltrating cells in the anterior chamber with hypopyon. The fundus was invisible due to intense vitreous opacity...
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Introduction: Thyroid-associated orbitopathy (TAO) is one of the most common autoimmune inflammatory disorders of the orbit. The presence of anti-thyroid antibodies is believed to play a role in the pathogenesis and clinical status of the TAO patients. Herein, we review the usefulness of TPOAb as a biomarker for TAO.Methods: A systematic search in MEDLINE library was conducted. Results: Twenty studies were included. TPO is expressed in orbital tissues, and the polymorphism rs11675434 SNP has pro...
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#1Lisa Scifo (ULB: Université libre de Bruxelles)H-Index: 1
#2Francois Willermain (ULB: Université libre de Bruxelles)H-Index: 16
Last. D Makhoul (ULB: Université libre de Bruxelles)H-Index: 3
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Purpose: To describe subclinical chorioretinal lesions revealed by indocyanine green angiography (ICGA) and their evolution under systemic treatment in tubulointerstitial nephritis and uveitis (TINU) patients.Methods: Retrospective case series of three patients with TINU syndrome. Choroidal and retinal involvement were assessed by fluorescein angiography (FA) and ICGA.Results: Three patients were analyzed. FA demonstrated hot disc, associated in two cases with retinal vascular leakage, and ICGA ...
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#2Josef Huemer (Moorfields Eye Hospital)H-Index: 5
Last. Giuseppe CasalinoH-Index: 12
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Purpose: To report acute macular neuroretinopathy (AMN) in two young women two days after receiving Vaxzevria Coronavirus disease (COVID-19) vaccination.Methods: Observational case reports.Observation: The first patient was an Italian 22-year-old female with acute onset of paracentral scotoma two days post vaccination. The second patient was an Austrian 28-year-old female who presented with sudden onset paracentral scotoma two days after vaccination. Multimodal retinal imaging was consistent wit...
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#1Abdulrahman F AlBloushi (KSU: King Saud University)H-Index: 3
#2Saad H AlEnezi (KSU: King Saud University)H-Index: 2
Last. Ahmed M. Abu El-Asrar (KSU: King Saud University)H-Index: 39
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Purpose: To investigate the outcomes of uveitis associated with Vogt-Koyanagi-Harada (VKH) disease in pediatric age group (aged 16 years and under).Methods: A retrospective review of patients with VKH disease.Results: Among the 244 patients identified, 38 (76 eyes) were children. Among them, five had insulin-dependent diabetes mellitus. 21 presented with initial-onset acute disease and 17 with chronic recurrent disease. The mean follow-up period was 59.1 months. At presentation, chronic recurren...
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#1Sepehr Feizi (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 19
#2Mohammadhasan Alemzadeh-Ansari (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 1
Last. Ahmad Kheirkhah (University of Texas at Austin)H-Index: 25
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Purpose: To investigate the safety and efficacy of topical erythropoietin for the treatment of scleral necrosis.Methods: This study enrolled eight consecutive patients with scleral necrosis due to previous ocular surgery, rheumatoid arthritis-associated necrotizing anterior scleritis, and thermal and chemical burns. Conventional treatments failed to heal avascular scleral lesions in all eyes. Patients were treated with topical erythropoietin (3000 IU/mL) four times a day.Results: The mean patien...
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Ophthalmology
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