ACS Medicinal Chemistry Letters
Papers 3,221
1 page of 323 pages (3,221 results)
#1Yoshihide Hattori (OPU: Osaka Prefecture University)H-Index: 10
#2Miki Ishimura (OPU: Osaka Prefecture University)H-Index: 6
Last. Mitsunori Kirihata (OPU: Osaka Prefecture University)H-Index: 18
view all 6 authors...
We developed novel closo-dodecaborate ([B12H11]2–) anion-containing translocator protein (TSPO) ligand as a boron carrier for boron neutron capture therapy. This compound shows high water solubilit...
#1Aldo PeschiulliH-Index: 3
#2Daniel OehlrichH-Index: 19
Last. Harrie J.M. GijsenH-Index: 22
view all 14 authors...
We recently disclosed a set of heteroaryl-fused piperazine inhibitors of BACE1 that combined nanomolar potency with good intrinsic permeability and low Pgp-mediated efflux. Herein we describe furth...
#1Barbara Schroeder (FU: Freie Universität Berlin)H-Index: 1
#2Peter Demirel (FU: Freie Universität Berlin)
Last. Jörg Rademann (FU: Freie Universität Berlin)H-Index: 33
view all 12 authors...
Viral proteases have been established as drug targets in several viral diseases including human immunodeficiency virus and hepatitis C virus infections due to the essential role of these enzymes in...
#1Ram W. SabnisH-Index: 1
#1Ram W. SabnisH-Index: 1
#1Abigail N Smith (Vanderbilt University)H-Index: 2
#2Daniel J. Blackwell (VUMC: Vanderbilt University Medical Center)H-Index: 9
Last. Jeffrey N. Johnston (Vanderbilt University)H-Index: 34
view all 4 authors...
Hit-to-lead studies employ a variety of strategies to optimize binding to a target of interest. When a structure for the target is available, hypothesis-driven structure–activity relationships (SAR...
#1Ram W. SabnisH-Index: 1
#1Jacob W. Campbell (Dalhousie University)
#2Matthew T. Tung (University of Toronto)
Last. Alison Thompson (Dalhousie University)H-Index: 28
view all 6 authors...
The synthesis and characterization of the first BODIPY appended to the five-membered heterocylic tellurophene [Te] moiety is reported. By incorporating tellurophene at the meso position, the tellur...
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