Endocrine Journal
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1.95
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3956
Papers 3871
1 page of 388 pages (3,871 results)
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#1Tsukasa Kawakami (Fujita Health University)H-Index: 1
#2Haruki Fujisawa (Fujita Health University)
Last. Yoshihisa Sugimura (Fujita Health University)H-Index: 21
view all 10 authors...
Recently, chronic hyponatremia, even mild, has shown to be associated with poor quality of life and high mortality. The mechanism by which hyponatremia contributes to those symptoms, however, remains to be elucidated. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a primary cause of hyponatremia. Appropriate animal models are crucial for investigating the pathophysiology of SIADH. A rat model of SIADH has been generally used and mouse models have been rarely used. In this...
1 CitationsSource
#1Yoshimi Morita (Hiroshima University)
#2Haruya Ohno (Hiroshima University)H-Index: 15
Last. Masayasu Yoneda (Hiroshima University)H-Index: 16
view all 5 authors...
Japanese Americans living in the United States are genetically identical to Japanese people, but have undergone a rapid and intense westernization of their lifestyle. This study investigated variability in glucagon secretion after glucose loading among Japanese Americans with normal glucose tolerance (NGT) according to obesity status. The 75-g oral glucose tolerance test (OGTT) was performed for 138 Japanese Americans (aged 40-75 years) living in Los Angeles. Plasma glucagon levels measured usin...
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#1Sae Ishihara (OCU: Osaka City University)H-Index: 2
#2Naoyoshi Onoda (OCU: Osaka City University)H-Index: 27
Last. Masaichi Ohira (OCU: Osaka City University)H-Index: 32
view all 9 authors...
Anaplastic thyroid cancer (ATC) is a rarely occurring refractory disease. While recent clinical trials have demonstrated the efficacy of tyrosine kinase inhibitor (TKI) therapy for ATC, evidence is scarce in clinical practice. In this study, we reviewed our initial experiences with TKI treatment in ATC patients with the aim of revealing the efficacy and safety of the same in clinical practice. We retrospectively reviewed our experiences with TKI treatment use in ATC patients diagnosed at our ins...
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#1Takehiro Kitagawa (Memorial Hospital of South Bend)H-Index: 1
#2Tatsuya Ohtonari (Memorial Hospital of South Bend)H-Index: 4
Last. Kazuhiro Takekoshi (University of Tsukuba)H-Index: 21
view all 6 authors...
Metastatic paraganglioma (MPG) of the spine is a rare condition, with no established management. Herein, we report the longest survival case of a primary neck tumor that caused spinal MPG with a succinate dehydrogenase subunit B (SDHB) mutation (c.470delT, p.L157X) which could have promoted its malignancy. This male patient initially presented with ‍a left neck PG which was diagnosed by a biopsy when he was 54 years-old. Simultaneously performed additional examinations revealed the spinal metast...
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#1Guoqiang Fan (NAU: Nanjing Agricultural University)H-Index: 3
#2Yanfei Li (NAU: Nanjing Agricultural University)H-Index: 2
Last. Xiaojing Yang (NAU: Nanjing Agricultural University)H-Index: 14
view all 5 authors...
Skeletal muscle is the most abundant tissue in the adult body and plays an essential role in maintaining heat production for the entire body. Recently, muscle-derived non-shivering thermogenesis under cold conditions has received much attention. Zinc-α2-glycoprotein (ZAG) is an adipokine that was shown to influence energy metabolism in the adipose tissue. We used ZAG knock-out (ZAG KO) and wild-type (WT) mice to investigate the effect of ZAG on the lipid metabolism of skeletal muscle upon exposu...
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#1Tetsuro Niri (Nagasaki University)H-Index: 2
#2Ichiro Horie (Nagasaki University)H-Index: 13
Last. Atsushi Kawakami (Nagasaki University)H-Index: 42
view all 12 authors...
Idiopathic hypothalamitis is a rare condition that can cause anterior pituitary dysfunction and central diabetes insipidus (CDI), occasionally accompanied by a disturbance of autonomic regulation known as hypothalamic syndrome. This condition has been described as a subtype of autoimmune (lymphocytic) hypophysitis; however, some cases of isolated hypothalamic involvement with no inflammatory lesions in either the pituitary gland or infundibulum have been reported. The detailed epidemiology and p...
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#1Erkan Somuncu (UHSA: University of Health Sciences Antigua)
#2Yasin Kara (UHSA: University of Health Sciences Antigua)H-Index: 1
Quality of life (QoL) typically improves with a parathyroidectomy (PTx) in cases of primary hyperparathyroidism (PHPT), but the effect of surgery on QoL is not yet fully understood. This study evaluated the impact of PTx on health-related QoL (HRQoL). Patients who underwent PTx for PHPT between January 2016 and December 2019 were asked to complete the 36-Item Short Form Health Survey (SF-36) and the Primary Hyperparathyroidism Quality of Life (PHPQoL) questionnaire before surgery and 1 year late...
1 CitationsSource
#1Jianxin Li (PRC: China Medical University (PRC))H-Index: 1
#2Jing Li (PRC: China Medical University (PRC))H-Index: 14
Last. Zhaojun Yang (China-Japan Friendship Hospital)H-Index: 10
view all 14 authors...
Using the data from the trial of Metformin and AcaRbose in Chinese as the initial Hypoglycemic treatment (MARCH), this study was performed to compare the differential effects of acarbose and metformin on glucose metabolism after stratification by gender. Six hundred and forty patients who had finished the whole 48-week follow-up were included. The reduction of haemoglobin A1c (HbA1c) was comparable between acarbose- and metformin-treated patients among either females or males, and it was also si...
1 CitationsSource
#1Hiroshi Arima (Nagoya University)H-Index: 27
Last. San-E Ishikawa (International University of Health and Welfare)
view all 7 authors...
The purpose of this study was to determine the efficacy and safety of tolvaptan in Japanese patients with hyponatremia secondary to syndrome of inappropriate secretion of antidiuretic hormone (SIADH). This multicenter, open-label, dose-escalation, phase III study enrolled Japanese patients (20-85 years old) with hyponatremia secondary to SIADH who were unresponsive to fluid restriction. Oral tolvaptan was administered for up to 30 days, initially at 7.5 mg/day, but escalated daily as necessary, ...
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#1Yohei Masunaga (Hamamatsu University)H-Index: 2
#2Yasuko Fujisawa (Hamamatsu University)H-Index: 8
Last. Tsutomu Ogata (Hamamatsu University)H-Index: 53
view all 9 authors...
SHORT syndrome is a rare developmental disorder frequently associated with growth failure and insulin resistant diabetes mellitus (IRDM). Since GH has a diabetogenic effect, GH therapy has been regarded as a contraindication. We observed a Brazilian girl with SHORT syndrome who received GH therapy from 4 6/12 years of age for SGA short stature. GH dosage was increased from 0.23 to 0.36 mg/kg/week, but statural response to GH therapy remained poor. Her blood HbA1c level, though it remained 5.5-6....
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Endocrinology
Insulin
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Diabetes mellitus
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