Clinical Oncology
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3.11
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#1C.E. Shelley (Royal Surrey County Hospital)
Last. Alexandra J. Stewart (Royal Surrey County Hospital)H-Index: 16
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The complex and varied motion of the cervix-uterus target during external beam radiotherapy (EBRT) underscores the clinical benefits afforded by adaptive radiotherapy (ART) techniques. These gains have already been realised in the implementation of image-guided adaptive brachytherapy, where adapting to anatomy at each fraction has seen improvements in clinical outcomes and a reduction in treatment toxicity. With regards to EBRT, multiple adaptive strategies have been implemented, including a per...
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#1J. Lima (The Royal Marsden NHS Foundation Trust)
#2Z. Ali (The Royal Marsden NHS Foundation Trust)
Last. Susana Banerjee (ICR: Institute of Cancer Research)H-Index: 32
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Despite advances in the treatment of gynaecological malignancies, both recurrent endometrial and cervical cancers when not amenable to localised therapy (surgery or radiotherapy), remain incurable with limited prognosis and effective treatment options. Chemotherapy remains the standard of care for women with metastatic endometrial or cervical cancers. The addition of bevacizumab to first-line chemotherapy for metastatic cervical cancer patients represents a significant step forward in improving ...
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#1Umesh MahantshettyH-Index: 26
#2G. Lavanya (HBNI: Homi Bhabha National Institute)H-Index: 2
Last. N. Amornwichet (Chula: Chulalongkorn University)H-Index: 6
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Cervical cancer is one of the most common cancers in developing nations. It has had a tremendous impact on the lifetime of millions of women over the last century and continues to do so. In this collaborative clinicians' review, we highlight the incidence, treatment and clinical outcomes of cervical cancer in low-income (LICs) and low- and middle-income countries (LMICs) across Asia, South America, South Africa and Eastern Europe. With the cervical cancer burden and locally advanced cancers bein...
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#1S. Mutyala (UA: University of Arizona)
#2G. Patel (Montefiore Medical Center)
Last. Keyur J. Mehta (Montefiore Medical Center)H-Index: 8
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Endometrial cancer is a common gynaecological cancer, is typically early stage and treated with surgery. For patients where surgery is difficult or dangerous, definitive radiation therapy is the next best option. This study included a single institution case series (step 1) and a systematic review of the literature (step 2). In step 1, all endometrial cancer cases that were treated with definitive image-guided brachytherapy at a single institution from 2008 to 2020 were retrospectively analysed....
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#1I. Rizzuto (Royal Adelaide Hospital)
#2M.K. Oehler (Royal Adelaide Hospital)
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Abstract null null Modern multimodality cancer treatment has led to a rise in cancer survivors, and by 2030 the survival rate is estimated to increase by 31.4%. This is an impressive survival statistic on which clinicians and services continue to build. One of the less well-acknowledged consequences of survivorship among health professionals and patients alike is female sexual dysfunction, despite it occurring in more than 60% of women diagnosed with cancer. The systematic assessment and managem...
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#1Thomas Müdder (University Hospital Bonn)H-Index: 2
#2Gustavo R. Sarria (University Hospital Bonn)H-Index: 6
Last. Christina Leitzen (University Hospital Bonn)H-Index: 3
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AIMS To carry out a dosimetric comparison and constraints feasibility proof of adjuvant radiotherapy through helical tomotherapy or volumetric modulated arc therapy (VMAT) for malignant pleural mesothelioma patients after pleurectomy/decortication. MATERIALS AND METHODS Retrospective calculations were carried out on previously acquired simulations. A whole-pleura volume with 50.4 Gy in 28 fractions was prescribed, simulating a no residual tumour situation. Calculations were carried out using an ...
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#1L. Wang (Royal Surrey County Hospital)
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#1S.D. Robinson (Imperial College Healthcare)
#2J.D. Towler (Imperial College Healthcare)
Last. D.M. Gujral (Imperial College Healthcare)H-Index: 1
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#1Masoom A. Haider (U of T: University of Toronto)H-Index: 39
#2Janet E. Brown (McMaster University)H-Index: 46
Last. Andrew Loblaw (Sunnybrook Health Sciences Centre)H-Index: 35
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There has been growing utilisation of multiparametric magnetic resonance imaging (MPMRI) as a non-invasive tool to diagnose and localise clinically significant prostate cancer (CSPCa). This updated systematic review examines the use of MPMRI in patients with an elevated risk of CSPCa who have had a prior negative transrectal ultrasound systematic biopsy (TRUS-SB) and who were biopsy naive. MEDLINE, EMBASE and the Cochrane Database of Systematic Reviews were searched for existing systematic revie...
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