Neurological Research
Papers 4510
1 page of 451 pages (4,510 results)
#1Dongliang Wang (PKU: Peking University)H-Index: 7
#2Jiayu Liu (PKU: Peking University)H-Index: 4
Last. Ruen Liu (PKU: Peking University)H-Index: 3
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OBJECTIVE To analyze the causes of wire tethering in deep brain stimulation (DBS) and propose ways to prevent it. METHODS A total of 70 consecutive patients (140 electrodes) operated for DBS in our department from September 2017 to December 2019 were analyzed to document wire tethering, respectively, in the initial period (September 2017-June 2018) and the late period (July 2018-December 2019). The patients come back to our clinic 1 month postoperatively to turn on the equipment and followed up ...
#1Secil Ak Aksoy (Uludağ University)H-Index: 5
#2Melis Mutlu (Uludağ University)H-Index: 2
Last. Ismail Seckin Kaya (Uludağ University)
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Objective: This study was designed to conduct molecular classification based on IDH1/2, TERT, ATRX, and DAXX changes in pediatric and adult primary glioblastoma (GB) and to analyze the potential interaction of LncRNA MALAT1 in the determined homogeneous subgroups.Methods: We analyzed the expression profiles of ATRX/DAXX and MALAT1 using the qRT-PCR method and IDH and TERT mutation status using DNA sequencing analysis in 85 primary pediatric and adult GB patients.Results: IDH1 mutation was observ...
#1Oruç Yunusoğlu (Yüzüncü Yıl University)H-Index: 3
OBJECTIVE Alcohol abuse causes several neurological disorders. Resveratrol is a natural polyphenol that occurs as a phytoalexin. In different studies, it has been investigated that resveratrol has positive effects on various mechanisms that are important in drug addiction or substance use disorder. The objective of the present study was to examine the effect of resveratrol on alcohol-induced conditioned place preference (CPP) in mice. METHODS CPP was induced by intraperitoneal (i.p.) administrat...
#2Pietro Fiaschi (UniGe: University of Genoa)H-Index: 9
Last. Crescenzo CaponeH-Index: 2
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Background null In patients suffering from traction lesions of the brachial plexus, complete C5 and/or C6 root avulsion patients with C7 root preservation are relatively uncommon occurrences, but represent excellent candidates for surgical treatment, with satisfactory results. Shoulder abduction and extra-rotation, elbow flexion and forearm supination are lost functions restorable with surgical treatment. null Methods null This single-center, prospective observational study involved a series of ...
#1Karl RoesslerH-Index: 22
#2Burkhard S. Kasper (FAU: University of Erlangen-Nuremberg)H-Index: 22
Last. Michael BuchfelderH-Index: 91
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Objective: The aim of this retrospective cohort study was to assess seizure and memory outcomes following temporal lobe surgery in patients suffering from medically refractory temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS).Methods: A retrospective monocentric data analysis was performed in consecutive patients who were operated on during 2002-2018. In the first decennium, standard temporal lobe resections (TLR) were predominately performed, and later, antero-temporal lobe resections...
#1Guangwen Li (Qingdao University)H-Index: 3
#2Tonghui Liu (Qingdao University)H-Index: 3
Last. Yong Zhang (Qingdao University)H-Index: 3
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Objectives: To investigate the factors affecting the risk of recurrent stroke after intracranial artery stenting.Methods: This is a subgroup analysis of a prospective single-arm registry study with 20 participating sites. Patients aged 18-85 years old with symptomatic intracranial atherosclerotic stenosis caused by 70-99% stenosis combined with poor collaterals were included in this study. The median follow-up in this study was 26.4 months.Results: A total of 260 patients were recruited in this ...
#1Qingzhu Wang (Capital Medical University)H-Index: 1
#2Melissa Wills (WSU: Wayne State University)H-Index: 1
Last. Yuchuan Ding (Veterans Health Administration)H-Index: 4
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Objective: Exercise is an essential rehabilitative strategy after stroke butits implementation is limited as its very early use can exacerbate damage and is restricted by patient disability. Remote Ischemic Conditioning (RIC) is a safe alternative for post-stroke neuroprotetion. The present study investigated the neurorehabilitative benefits of early RIC followed by exercise (RICE) therapy.Methods: 48 adult male Sprague-Dawley rats were divided into groups: 1) sham, 2) stroke, 3) stroke with RIC...
#1Edoardo Bianchini (Sapienza University of Rome)H-Index: 3
#2Michela Sforza (Sapienza University of Rome)H-Index: 3
Last. Francesco E. Pontieri (Sapienza University of Rome)H-Index: 32
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Besides the inhibition of monoamine-oxidase-B, high-dose safinamide (100 mg) also blocks voltage-gated Na+ and Ca++ channels and inhibits glutamate release at overactive synapses. This latter mechanism may provide further benefit to fluctuating Parkinson's disease (PD) patients compared to rasagiline. Here, we retrospectively investigated the consequences of shifting from rasagiline to high-dose safinamide in PD patients reporting symptoms of wearing-off, defined by the Wearing-Off-Questionnaire...
Introduction: Subthalamic nucleus (STN) deep brain stimulation (DBS) is an important option in the treatment of motor symptoms and fluctuations in patients with advanced Parkinson's disease (PD). In addition to the improvement in motor symptoms, many studies have reported changes in some non-motor symptoms (NMS) after STN DBS.Method: 61 patients (42 males) who underwent STN DBS with advanced PD and 24 healthy controls (15 males) were included in the study. Autonomic symptoms (orthostatic hypoten...
#1Weizhe Li (USF: University of South Florida)
#2W. Scott Burgin (USF: University of South Florida)H-Index: 21
Last. Zeguang Ren (USF: University of South Florida)H-Index: 10
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Background:Rapid and effective revascularization is the cornerstone of acute ischemic stroke treatment. Endovascular thrombectomy reperfusion has dramatically changed patients' outcomes with large vessel occlusions. Results of randomized controlled trials have shown that the benefit of this treatment is highly time-sensitive. The purpose of this review is to introduce a new approach to acute stroke treatment - direct angiographic intervention for selected patients. Methods & Results:We examined ...
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