World Journal of Surgical Oncology
Papers 3,926
1 page of 393 pages (3,926 results)
#1Huanhuan Xu (NMU: Nanjing Medical University)H-Index: 1
#2Qi Liang (NMU: Nanjing Medical University)H-Index: 2
Last. Lingxiang Liu (NMU: Nanjing Medical University)H-Index: 21
view all 7 authors...
BACKGROUND HER2 is a member of the ERBB family of receptor tyrosine kinases, and HER2 mutations occur in 1-4% of non-small cell lung cancer (NSCLC) as an oncogenic driver mutation. We found a rare mutation of HER2 p.Asp769Tyr in NSCLC. CASE PRESENTATION We presented a case of a 68-year-old nonsmoking male patient with brain metastasis from lung adenocarcinoma harboring a rare mutation of HER2 p.Asp769Tyr. After multiple lines of treatment, he obtained a durable response (10 months) to afatinib a...
#1Weiyuan Li (Yunnan University)
#2Jiao Ma (Yunnan University)
Last. Chunjie Xiao (Yunnan University)
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BACKGROUND This study aims to screen and identify the biological functions and prognostic value of CXC chemokines in ovarian cancer (OC) through bioinformatics and molecular biology methods, and to provide data support for the selection of biomarkers and prognostic analysis of OC. METHODS In this study, GEO, ONCOMINE, GEPIA, cBioPortal, GeneMANIA, Metascape, STRING, TRRUST, and TIMER databases were used to study CXC chemokines. Angiogenesis and T cell killing assay were used to detect the effect...
#1jie Zhang (CSU: Central South University)
#2Weidong Liu (CSU: Central South University)H-Index: 2
Last. Baiyun Zhong (CSU: Central South University)H-Index: 1
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Background null Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites (SRMS) is a non-receptor tyrosine kinase that has been found to be overexpressed in various tumors. However, the role of SRMS in colorectal cancer (CRC) has not been well established. null Methods null We evaluated the expression levels of SRMS in CRC using GEPIA, Oncomine, and HPA datasets. Survival information and gene expression data of CRC were obtained from The Cancer Genome Atlas (...
#2Serdar ÇulcuH-Index: 1
Last. Ali Unal (Ankara University)H-Index: 25
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BACKGROUND In-transit metastasis is considered a locoregional disease in cutaneous melanoma (CM) patients. Isolated limb perfusion (ILP) is among the treatment options in selected cases. The aim of this study was to determine the success of pre- and post-perfusion mSIS values in predicting the potential complications and the prognosis of the disease by investigating the early and long-term results of mSIS values calculated before and after ILP in CM cases with in-transit metastases. MATERIALS AN...
#1Weixia Wang (Fudan University)H-Index: 2
#2Hongyan Jing (Fudan University)H-Index: 2
Last. Jing Liu (Fudan University)H-Index: 2
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Background null The effect of schistosomiasis on CD8+ T cells and then on PD-L1 expression was unknown, and the utility of CD8+ TILs as a biomarker for schistosomal-associated colorectal cancer (SCRC) rarely has been reported. null Methods null Three hundred thirty-eight patients with colorectal cancer (CRC) were enrolled. Immunohistochemical analysis was conducted to evaluate the expression of PD-L1 and the infiltration of CD8+ T cells. null Results null In the total cohort, the results showed ...
#1Jie He (CSU: Central South University)
#2Chaojie Zhang (HNU: Hunan Normal University)
Last. Fada Xia (CSU: Central South University)
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BACKGROUND Carbon nanoparticles (CNs) are tracers used in thyroid surgery of patients with thyroid cancer (TC) to help remove lymph nodes and protect the parathyroid gland. The facilitative effect of carbon nanoparticles in endoscopic thyroidectomy and prophylactic central neck dissection (pCND) has not been reported. METHODS The protective effect on parathyroid gland (PG) function and the numbers of identified parathyroid glands and central lymph nodes in endoscopic thyroid surgery through the ...
#1Yu Mu (Jilin University)
#2Linxian Zhao (Jilin University)
Last. Jiannan Li (Jilin University)H-Index: 5
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BACKGROUND Protective ileostomy is always applied to avoid clinically significant anastomotic leakage and other postoperative complications for patients receiving laparoscopic rectal cancer surgery. However, whether it is necessary to perform the ileostomy is still controversial. This meta-analysis aims to analyze the efficacy of ileostomy on laparoscopic rectal cancer surgery. METHODS Cochrane Library, EMBASE, Web of Science, and PubMed were applied for systematic search of all relevant literat...
#1Lu Fang (Anhui Medical University)H-Index: 4
#2Huan Li (Anhui Medical University)H-Index: 1
Last. Dexin Yu (Anhui Medical University)H-Index: 16
view all 9 authors...
BACKGROUND Adherent perinephric fat (APF), characterized by inflammatory fat surrounding the kidney, can limit the isolation of renal tumors and increase the operative difficulty in laparoscopic partial nephrectomy (LPN). The aim of this study was to investigate the predictors of APF and its impact on perioperative outcomes during LPN. METHODS A total of 215 consecutive patients undergoing LPN for renal cell carcinoma (RCC) from January 2017 to June 2019 at our institute were included. We divide...
#1Noriyuki Hirahara (Shimane University)H-Index: 16
#2Takeshi Matsubara (Shimane University)H-Index: 9
Last. Yoshitsugu Tajima (Shimane University)H-Index: 20
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BACKGROUND Risk factors for anastomotic leakage include local factors such as excessive tension across anastomosis and increased intraluminal pressure on the gastric conduit; therefore, we consider the placement of a nasogastric tube to be essential in reducing anastomotic leakage. In this study, we devised a safe and simple technique to place an NGT during an end-to-side, automatic circular-stapled esophagogastrostomy. METHODS First, a 4-0 nylon thread is fixed in the narrow groove between the ...
#1Zeyuan Qiang (Henan University)H-Index: 1
#2Haofeng Zhang (Zhengzhou University)
Last. Haibo Yu (Zhengzhou University)H-Index: 7
view all 7 authors...
Background null The aim of this study was to investigate the prognostic value of arginase-1 (Arg-1) and glypican-3 (GPC-3) in patients with intrahepatic cholangiocarcinoma (ICC). null Methods null Two hundred and thirty-seven patients with ICC were included in this study. All patients had undergone radical surgery and had complete clinical information. Immunohistochemistry was used to assess the levels of Arg-1 and GPC-3 in ICC tissues. Univariate and multivariate analyses were conducted to iden...
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