Journal of Bone and Mineral Metabolism
Papers 2,343
1 page of 235 pages (2,343 results)
#1Gang Zhao (Kunming Medical University)
#2Luo Wendong (Kunming Medical University)
Last. Jun Shu (Kunming Medical University)
view all 9 authors...
Human umbilical cord blood-derived MSCs (hUC-MSCs) have the potential to differentiate into osteoblasts. This study investigated the function and potential mechanisms of a novel lncRNA LINC02381 in hUC-MSC osteogenic differentiation. hUC-MSCs were maintained in osteogenic differentiation medium. RT-qPCR assay was performed to assess LINC02381 expression. Alizarin Red S (ARS) and alkaline phosphatase (ALP) staining were performed to evaluate osteogenic differentiation. The interaction between miR...
#1Shun Okuwaki (University of Tsukuba)H-Index: 3
#2Toru Funayama (University of Tsukuba)H-Index: 11
Last. Masashi Yamazaki (University of Tsukuba)H-Index: 54
view all 11 authors...
We aimed to investigate the risk factors that affect vertebral deformity 6 months after osteoporotic vertebral fractures (OVFs) at the time of injury. From May 2017 to May 2020, 70 postmenopausal women with OVFs were evaluated for age; body mass index; number of previous OVFs; total 25-hydroxy vitamin D [25(OH)D] levels; posterior wall injury on computed tomography; cross-sectional area (CSA) of the psoas major, erector spinae, and multifidus; fat infiltration; vertebral instability (VI) upon ad...
#1Arjan C.Y. Loenen (TU/e: Eindhoven University of Technology)H-Index: 1
#2Marloes Peters (UM: Maastricht University)H-Index: 4
Last. Paul C. Willems (UM: Maastricht University)H-Index: 24
view all 7 authors...
Although computed tomography (CT) can identify the presence of eventual bony bridges following lumbar interbody fusion (LIF) surgery, it does not provide information on the ongoing formation process of new bony structures. 18F sodium fluoride (18F-NaF) positron emission tomography (PET) could be used as complementary modality to add information on the bone metabolism at the fusion site. However, it remains unknown how bone metabolism in the operated segment changes early after surgery in uncompr...
#1Lysette Iglesias (Winthrop-University Hospital)H-Index: 1
#2James K. Yeh (Winthrop-University Hospital)H-Index: 39
Last. John F. Aloia (Winthrop-University Hospital)H-Index: 58
view all 4 authors...
#1Hun Jee Choe (Seoul National University Hospital)
#2Bo Kyung Koo (Seoul Metropolitan Government)H-Index: 18
Last. Sang Wan Kim (Seoul Metropolitan Government)H-Index: 30
view all 8 authors...
Bone loss caused by primary hyperparathyroidism (PHPT) is an indication for parathyroidectomy (PTX). However, whether adding bisphosphonates would be superior to PTX alone to increase bone mass remains unclear. We thus aimed to compare the skeletal effects of the combination treatment of bisphosphonates and PTX with PTX alone. In this retrospective analysis, bone mineral density (BMD) changes after 1 year of combination treatment and PTX alone were compared. We also analyzed the correlation betw...
#1Chuanmei He (Bengbu Medical College)
#2Mingming Liu (Bengbu Medical College)
Last. Tongdao Xu (Bengbu Medical College)
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Diabetic osteoporosis (DOP) is a chronic diabetic complication, which is attributed to high glucose (HG)-induced dysfunction of bone marrow mesenchymal stem cells (BMSCs). Studies have revealed that microRNAs (miRNAs) play critical roles in osteogenic differentiation of BMSCs in DOP. Here, the role of miR-9-5p in DOP progression was explored. The rat model of DOP was established by intraperitoneal injection of streptozotocin (STZ). BMSCs were treated with high glucose (HG) to establish in vitro ...
#1Taizo Kaneko (UTokyo: University of Tokyo)H-Index: 1
#2Keisuke Horiuchi (National Defense Medical College)H-Index: 33
Last. Taku Saito (UTokyo: University of Tokyo)H-Index: 32
view all 11 authors...
A disintegrin and metalloproteinase 17 (Adam17), also known as TNFα-converting enzyme (Tace), is a membrane-anchored protein involved in shedding of TNF, IL-6 receptor, ligands of epidermal growth factor receptor (EGFR), and Notch receptor. This study aimed to examine the role of Adam17 in adult articular cartilage and osteoarthritis (OA) pathophysiology. Adam17 expression was examined in mouse knee joints during OA development. We analyzed OA development in tamoxifen-inducible chondrocyte-speci...
#1Minako Wakasugi (Niigata University)H-Index: 15
#2Akio Yokoseki (Niigata University)H-Index: 14
Last. Ichiei Narita (Niigata University)H-Index: 56
view all 9 authors...
Introduction null Polypharmacy is associated with an increased risk of fracture in aging populations, but no study has accounted for the impact of kidney function on this association. This study aimed to examine the association between polypharmacy and incident fragility fracture based on chronic kidney disease (CKD) status. null Materials and methods null Participants were 2023 patients (55% men; mean age, 69 years) of Sado General Hospital enrolled in the Project in Sado for Total Health (PROS...
#1Chang Kyun Choi (Chonnam National University)H-Index: 4
#2Sun-Seog Kweon (Chonnam National University)H-Index: 34
Last. Min-Ho Shin (Chonnam National University)H-Index: 34
view all 8 authors...
Many previous studies have reported a positive relationship between alcohol and bone mineral density (BMD). However, the causality between alcohol and BMD has not been fully evaluated. This study enrolled 8892 participants from the Dong-gu study. Mendelian randomization (MR) using two-stage least-squared regression was used to evaluate the association between the genetically predicted amount of alcohol consumption per day and BMD. The aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism was used ...
#1Qian Liang (SYSU: Sun Yat-sen University)H-Index: 2
#2Yingsi Lu (SYSU: Sun Yat-sen University)H-Index: 1
Last. Chengming Zhu (SYSU: Sun Yat-sen University)H-Index: 2
view all 11 authors...
Heterotopic ossification of tendons and ligaments is a painful and debilitating disease with no effective treatment. Although aging has been reported to be correlated with the occurrence and development of this disease, the mechanism remains unknown. In the present study, we generated Bmal1-/- mice, which disrupted the circadian clock and displayed premature aging, as an aging model to explore the role of Bmal1 in TGF-beta (β)/BMP signaling in progressive heterotopic ossification of tendons and ...
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