International Journal for Numerical Methods in Biomedical Engineering
Papers 1108
1 page of 111 pages (1,108 results)
#1Xinyu Tong (BIT: Beijing Institute of Technology)
#2Jia Dong (Capital Medical University)
Last. Duanduan Chen (BIT: Beijing Institute of Technology)H-Index: 13
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Fenestration is a rare congenital abnormality that refers to a segmental duplication of arteries. It is still not clear about the role of fenestrations in the etiology and pathological evolution of vascular diseases. This study aims to investigate the hemodynamic influence brought by various sizes and locations of fenestration in basilar artery models. A series presumptive fenestration models were established based on a normal basilar artery model with various sizes and locations. Identical boun...
#1R. Krishna Priya (National University of Science and Technology)H-Index: 1
#2Susamma Chacko (National University of Science and Technology)
A central nervous system (CNS) disease affecting the insulating myelin sheaths around the brain axons is called multiple sclerosis (MS). In today's world, MS is extensively diagnosed and monitored using the MRI, because of the structural MRI sensitivity in dissemination of white matter lesions with respect to space and time. The main aim of this study is to propose Multiple Sclerosis Lesion Segmentation in Brain MRI imaging using Optimized Deep Convolutional Neural Network and Super-pixel Cluste...
#1Thomas Grandits (Graz University of Technology)H-Index: 3
#2Alexander Effland (Graz University of Technology)H-Index: 6
Last. Simone Pezzuto (USI: University of Lugano)H-Index: 10
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The identification of the initial ventricular activation sequence is a critical step for the correct personalization of patient-specific cardiac models. In healthy conditions, the Purkinje network is the main source of the electrical activation, but under pathological conditions the so-called earliest activation sites (EASs) are possibly sparser and more localized. Yet, their number, location and timing may not be easily inferred from remote recordings, such as the epicardial activation or the 1...
#1Abhignyan Nagesetti (FIU: Florida International University)H-Index: 8
#2George S. Dulikravich (FIU: Florida International University)H-Index: 29
Last. Anthony J. McGoron (FIU: Florida International University)H-Index: 22
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Drug delivery to tumors suffers from poor solubility, specificity, diffusion through the tumor micro-environment and nonoptimal interactions with components of the extracellular matrix and cell surface receptors. Nanoparticles and drug-polymer complexes address many of these problems. However, large size exasperates the problem of slow diffusion through the tumor. Three-dimensional tumor spheroids are good models to evaluate approaches to mitigate these difficulties and aid in design strategies ...
#1Li Guotong (Beijing University of Technology)
#2Jianfeng Li (Beijing University of Technology)H-Index: 5
Last. Mingjie Dong (Beijing University of Technology)H-Index: 5
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The Ortho-SUV frame (OSF) is a hexapod external fixator widely applied in orthopedics deformity correction. The possibility of collision between OSF's struts and the soft tissue is an essential but overlooked issue. To avoid the issue, a novel collision detection algorithm is established based on a cone-cylinder model of the tibial limb-strut interaction for detecting the closeness of the tibial limb and external fixator. The algorithm is constructed using the vector analysis based on the model ...
#1Samuele L Gould (UNIBO: University of Bologna)
#2Luca Cristofolini (UNIBO: University of Bologna)H-Index: 44
Last. Marco Viceconti (UNIBO: University of Bologna)H-Index: 67
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Scoliosis is a deformity of the spine that in severe cases requires surgical treatment. There is still disagreement among clinicians as to what the aim of such treatment is as well as the optimal surgical technique. Numerical models can aid clinical decision making by estimating the outcome of a given surgical intervention. This paper provided some background information on the modelling of the healthy spine and a review of the literature on scoliotic spine models, their validation, and their ap...
#1Chen Onn Leong (UM: University of Malaya)H-Index: 3
#2Chin Neng Leong (UNSW: University of New South Wales)H-Index: 4
Last. Einly Lim (UM: University of Malaya)H-Index: 19
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Infarct extension involves necrosis of healthy myocardium in the border zone (BZ), progressively enlarging the infarct zone (IZ) and recruiting the remote zone (RZ) into the BZ, eventually leading to heart failure. The mechanisms underlying infarct extension remain unclear, but myocyte stretching has been suggested as the most likely cause. Using human patient-specific left-ventricular (LV) numerical simulations established from cardiac magnetic resonance imaging (MRI) of myocardial infarction (...
#1Hangkai Shen (THU: Tsinghua University)H-Index: 2
Last. Weiqiang Liu (THU: Tsinghua University)H-Index: 15
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Lumbar spinal fusion may cause adjacent segment degeneration (ASD) in the long term. Recently, inserting an interspinous process device (IPD) proximal to the fusion has been proposed to prevent ASD. The aim of this study was to investigate the biomechanics of lumbar fusion with proximal IPD implantation (LFPI) under both static loads and whole body vibration (WBV). A previously validated finite element (FE) model of the L1-5 lumbar spine was modified to simulate L4-5 fusion. Three different IPDs...
#1Bernard Helou (University of Rennes)
#2Aline Bel-Brunon (INSA Lyon: Institut national des sciences Appliquées de Lyon)H-Index: 4
Last. Pascal Haigron (University of Rennes)H-Index: 21
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In this work we propose a generic modeling approach for simulating percutaneous transluminal angioplasty (PTA) endovascular treatment, and evaluating the influence of balloon design, plaque composition, and balloon sizing on acute post-procedural outcomes right after PTA, without stent implantation. Clinically-used PTA balloons were classified into two categories according to their compliance characteristics, and were modeled correspondingly. Self-defined elastoplastic constitutive laws were imp...
#1Gareth A. Jones (Swansea University)H-Index: 22
#1Gareth P. Jones (Swansea University)H-Index: 8
Last. Sanjay Pant (Swansea University)H-Index: 10
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This study creates a physiologically realistic virtual patient database (VPD), representing the human arterial system, for the primary purpose of studying the effects of arterial disease on haemodynamics. A low dimensional representation of an anatomically detailed arterial network is outlined, and a physiologically realistic posterior distribution for its parameters constructed through the use of a Bayesian approach. This approach combines both physiological/geometrical constraints and the avai...
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