BMC Nephrology
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#1John P. Burke (Royal Brisbane and Women's Hospital)H-Index: 76
Last. D. Ranganathan (Griffith University)H-Index: 2
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BACKGROUND Percutaneous kidney biopsy is the gold standard investigation for the diagnosis of kidney diseases. The associated risks of the procedure depend on the skill and experience of the proceduralist as well as the characteristics of the patient. The Kidney Health Australia - Caring for Australasians with Renal Impairment (KHA-CARI) guidelines on kidney biopsies, published in 2019, are the only published national kidney biopsy guidelines. As such, this study surveys current kidney biopsy pr...
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#1Yong WangH-Index: 9
Last. Xiangmei ChenH-Index: 46
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BACKGROUND Chronic kidney disease (CKD) has become a global public health problem. Accumulating evidence suggested that vitamins play important roles in the progression of CKD. METHODS A cross-sectional study was conducted to investigate the vitamin status of patients with CKD at stage 1-5. The serum concentrations of 9 vitamins, vitamin A, B1, B2, B6, B9, B12, C, D, and E were measured by electroanalytical method with a Multi-Vitamin Analyzer. Pearson correlation and multiple linear regression ...
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#1Yijia Jiang (Beijing Chao-Yang Hospital)
#2Xiuming Xi (Capital Medical University)H-Index: 16
Last. Wenxiong Li (Beijing Chao-Yang Hospital)H-Index: 1
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BACKGROUND Acute kidney injury (AKI) newly-emerged in intensive care unit (ICU), has not been thoroughly studied in previous researches, is likely to differ from AKI developed before ICU admission. This study aimed to evaluate the incidence, risk factors, clinical features and outcome of new-onset AKI in critically ill patients. METHODS The data of present study derived from a multicenter, prospective cohort study in17 Chinese ICUs (January 2014 - August 2015). The incidence, risk factors, clini...
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Objective null Long noncoding RNA (lncRNA) taurine upregulated gene 1 (TUG1) is increased under the condition of ischemia. This study intended to identify the mechanism of TUG1 in renal ischemia-reperfusion (I/R). null Methods null First, a rat model of acute renal injury induced by I/R was established, followed by the measurement of blood urea nitrogen (BUN), serum creatine (SCr), methylenedioxyphetamine (MDA) and superoxide dismutase (SOD) in the serum of rats. TUG1 was knocked down in I/R rat...
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#1Koichiro Kajiwara (Fukuoka Dental College)H-Index: 1
#2Yoshihiko Sawa (Okayama University)H-Index: 19
Background null The overexpression of sodium-glucose cotransporter 2 (SGLT2) in diabetic kidneys has been reported. It has also been established that the diabetic glomerular endothelium expresses the toll-like receptors TLR2 and TLR4. The present study aims to examine the renal SGLT2 induction by the TLR2/4 ligand Porphyromonas (P.) gingivalis lipopolysaccharide (Pg-LPS) in mouse diabetic nephropathy. null Methods null Immunohistochemical study and tissue RT-PCR analyses were performed on mouse ...
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#1Davide SparasciH-Index: 1
Last. Mauro Manconi (USI: University of Lugano)H-Index: 37
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#1Ling Hou (PRC: China Medical University (PRC))H-Index: 4
#2Lu Yin (PRC: China Medical University (PRC))
Last. Yue Du (PRC: China Medical University (PRC))H-Index: 3
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Background null Crescentic glomerulonephritis is a disease characterized by severe glomerular injuries that is classified into five different pathological types. Patients with type V disease have pauci-immune crescentic glomerulonephritis (PICGN) that is negative for anti-neutrophil cytoplasmic autoantibodies (ANCAs). There are limited clinical data on the manifestations, treatment, and prognosis of type V crescentic glomerulonephritis, especially in children. null Case presentation null A 13-ye...
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#1Khoa Vu (UMN: University of Minnesota)H-Index: 3
#2Zhou J (UMN: University of Minnesota)
Last. Pinar Karaca-Mandic (NBER: National Bureau of Economic Research)H-Index: 21
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BACKGROUND Variation in de-adoption of ineffective or unsafe treatments is not well-understood. We examined de-adoption of erythropoiesis-stimulating agents (ESA) in anemia treatment among patients with chronic kidney disease (CKD) following new clinical evidence of harm and ineffectiveness (the TREAT trial) and the FDA's revision of its safety warning. METHOD We used a segmented regression approach to estimate changes in use of epoetin alfa (EPO) and darbepoetin alfa (DPO) in the commercial, Me...
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#1K. Lindhard (Herlev Hospital)
Last. D. Hansen (Herlev Hospital)
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An arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis treatment. After creation many of the AVFs will never mature or if functioning will need an intervention within 1 year due to an AVF stenosis. Studies investigating possible therapies that improves the AVF maturation and survival are scarce. Far infrared therapy (FIR) has shown promising results. In minor single centre and industry supported trials FIR has shown improved AVF maturation and survival. There is a need ...
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#1Kunaal Kharbanda (MAHSC: Manchester Academic Health Science Centre)
#2Osasuyi Iyasere (Leicester General Hospital)H-Index: 9
Last. Sandip Mitra (Royal Hallamshire Hospital)H-Index: 19
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BACKGROUND NICE Guideline NG107, "Renal replacement therapy and conservative management" (Renal replacement therapy and conservative management (NG107); 2018:1-33) was published in October 2018 and replaced the existing NICE guideline CG125, "Chronic Kidney Disease (Stage 5): peritoneal dialysis" (Chronic kidney disease (stage 5): peritoneal dialysis | Guidance | NICE; 2011) and NICE Technology Appraisal TA48, "Guidance on home compared with hospital haemodialysis for patients with end-stage ren...
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Top fields of study
Internal medicine
Renal function
Intensive care medicine
Kidney disease
Nephrology
Diabetes mellitus
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