Clinical Biochemistry
Papers 9,730
1 page of 973 pages (9,730 results)
#1Brooke M. Katzman (Mayo Clinic)H-Index: 4
#2Amy M. Wockenfus (Mayo Clinic)H-Index: 7
Last. Leslie J. Donato (Mayo Clinic)H-Index: 19
view all 5 authors...
Rapid and widespread diagnostic testing is critical to providing timely patient care and reducing transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Recently, the Visby Medical COVID-19 point of care (POC) test was granted emergency use authorization (EUA) for qualitative detection of SARS-CoV-2 nucleic acid at the point of care. We evaluated its performance characteristics using residual specimens (n = 100) collected from Mayo Clinic patients using nasopharyngeal (NP)...
#1Alexander Jordan (Dalhousie University)
#2Ali Sherazi (SJRH: Saint John Regional Hospital)
Last. Jennifer L. Shea (Dalhousie University)H-Index: 14
view all 7 authors...
Abstract null null Introduction null The type of blood collection tube used when obtaining samples for therapeutic drug monitoring (TDM) has important implications on the accuracy of results. Serum tubes without a gel separator are currently considered best practice. We sought to evaluate the performance of of Barricor™, a novel plasma tube that utilizes an inert mechanical separator, as well as a gel-based tube (PST™) for testing acetaminophen, digoxin, gentamicin, methotrexate, phenobarbital, ...
#1Muna Abdulridha Al-Barqaawi (University of Kufa)
#2Thekra Abdul-Jabr (University of Kufa)
Last. Majid Kadhum Hussain (University of Kufa)H-Index: 3
view all 6 authors...
BACKGROUND Coronary artery disease (CAD) is the primary cause of death worldwide. It is mainly caused by atherosclerosis that initiates from a genetic-environmental interaction. Studies highlighted the association of numerous gene polymorphisms with CAD. Omentin-1 is secreted from visceral adipose tissues, intestine, and others; it has anti-inflammatory and insulin sensitivity improving roles. AIM To explore the association of the omentin-1 gene polymorphisms (rs2274907 and rs2274908) with serum...
#1Idris Bugra Cerik (Cumhuriyet University)H-Index: 3
#2Ferhat DindaşH-Index: 1
Last. İbrahim Gül (Cumhuriyet University)H-Index: 9
view all 7 authors...
Abstract null null Introduction null Idiopathic pulmonary hypertension(IPAH) is a rare disease that causes severe morbidity and mortality despite advances in treatment management. Evaluating the prognosis of the disease is critical in determining therapeutic approaches. We aimed to evaluate the prognostic significance of C-reactive protein/albumin ratio (CAR) and uric acid, which is an easily applicable and inexpensive parameter in patients with IPAH. null null null Methods null Seventy-two IPAH...
#1Jens Kristian Munk (Hvidovre Hospital)H-Index: 4
#2Margrethe F. Hansen (Hvidovre Hospital)
Last. Henrik L. Jørgensen (UCPH: University of Copenhagen)H-Index: 25
view all 6 authors...
Abstract null null As healthcare costs continue to rise throughout the world, critical assessment of the appropriateness of expenses gain focus. Objectives: We aimed to describe the developments in test numbers of the 10 most frequently requested tests, and to simulate the effect of introducing minimal retesting intervals. Design & Methods: Data from the blood tests – albumin, alanine transaminase, cholesterol, creatinine, C-reactive protein, hemoglobin, hemoglobin A1c, potassium, sodium, and th...
#1Raül Rigo-Bonnin (HUB: Bellvitge University Hospital)H-Index: 7
#2Víctor-Daniel Gumucio-Sanguino (HUB: Bellvitge University Hospital)
Last. Joan Sabater-Riera (HUB: Bellvitge University Hospital)H-Index: 5
view all 12 authors...
Abstract null null Background null Currently, good prognosis and management of critically ill patients with COVID-19 are crucial for developing disease management guidelines and providing a viable healthcare system. We aimed to propose individual outcome prediction models based on binary logistic regression (BLR) and artificial neural network (ANN) analyses of data collected in the first 24 hours of intensive care unit (ICU) admission for patients with COVID-19 infection. We also analysed differ...
Abstract null null Background null null Anti-Sry-like null high mobility group null box 1 (anti SOX-1) proteins are rare onconeural antibodies associated with paraneoplastic Lambert-Eaton myasthenic syndrome (LEMS). Few patients with anti-SOX-1 antibodies and negative anti-glial null null nuclear antibody null reactivity have been described to date. null null null Case subject and methods null null Our case involves a 72-year-old female patient with progressive girdle weakness, sensation of heav...
#1A. Cossart (UQ: University of Queensland)H-Index: 2
#2Christine E. Staatz (UQ: University of Queensland)H-Index: 30
Last. Katherine A. Barraclough (University of Melbourne)H-Index: 20
view all 4 authors...
Abstract null null Therapeutic monitoring (TDM) of mycophenolic acid (MPA) has the potential to improve drug inefficacy and toxicities in kidney transplantation. However, measurement of plasma MPA concentrations is laborious and invasive. This study examined the utility of saliva compared with plasma based TDM of MPA. Paired blood and saliva samples were collected from 47 adult kidney transplant recipients pre- and at 1-, 2-, and 4-hours post mycophenolate mofetil administration. No relationship...
#1M.A. KarsdalH-Index: 5
#2Federica GenoveseH-Index: 23
Last. L. Jennings (Novartis)
view all 15 authors...
Abstract null null Objectives null There is a need for precision medicine and an unspoken promise of an optimal approach for identification of the right patients for value-based medicine based on big data. However, there may be a misconception that measurement of proteins is more valuable than measurement of fewer selected biomarkers. In population-based research, variation may be somewhat eliminated by quantity. However, this fascination of numbers may limit the attention to and understanding o...
#1Ummuhan Oncul (Ankara University)H-Index: 1
#2Fatma Tuba Eminoğlu (Ankara University)H-Index: 3
Last. Zehra Aycan (Ankara University)H-Index: 20
view all 6 authors...
OBJECTIVES Biotin therapy can affect the results of many immunoassay procedures. The present study investigates biotin's interference on 25-hydroxy vitamin D (25-OHD), parathyroidhormone (PTH) and thyroid-stimulating hormone (TSH) tests using four different assay systems and biotin neutralization. DESIGN AND METHODS Enrolled in the study were 50 children diagnosed with biotinidase deficiency (BTD) undergoing treatment with biotin (5-20 mg/day) who were subjected to a series of analyses involving...
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