Kidney & Blood Pressure Research
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Introduction null Albuminuria is a risk factor for macro- and microvascular complications of type 2 diabetes (T2D).With an increasing trend of normoalbuminuria, however, of the 2 predictors - estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR) - which one is a better predictor of vascular complications of T2D is not clear. null Objective null This study aimed to compare the impacts of albuminuria and eGFR on patients with T2D associated with micro- and macrov...
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#1Yuta YoshizawaH-Index: 1
#2Michihiro HosojimaH-Index: 13
Last. Ichiei NaritaH-Index: 55
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#1Wenkai Xiao (Chinese PLA General Hospital)H-Index: 12
#2Ping Ye (Chinese PLA General Hospital)H-Index: 15
Last. Xiaona Wang (Chinese PLA General Hospital)H-Index: 5
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BACKGROUND Whether elevated plasma total homocysteine (tHcy) is a risk factor for the progression of kidney disease in general population has not been well established. The purpose of this study was to investigate the prognostic properties of plasma tHcy for renal function decrement and early chronic kidney disease (CKD) in community-dwelling populations with normal renal function at baseline. METHODS A total of 1,426 participants were enrolled and followed for a median of 4.8 years (interquarti...
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#1Lei Zhang (SDU: Shandong University)
Last. Min Ma
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Background null LncRNAs play regulatory roles in diverse nephrological disorders, including renal cancer. Overexpression of lncRNA POU3F3 (POU3F3) has only been reported in esophageal squamous-cell carcinomas, indicating POU3F3 may be an oncogene in this disease. LncRNA GAS5 (GAS5) was reported to be a suppressor in various tumors. However, the roles and underlying mechanism of POU3F3 and GAS5 involved in renal cell carcinoma (RCC) remain unknown. null Methods null Real-time quantitative PCR and...
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#1Hui LiewH-Index: 1
#2Matthew A RobertsH-Index: 22
Last. Lawrence P. McMahonH-Index: 26
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INTRODUCTION The endothelial glycocalyx on the vascular luminal surface contributes to endothelial health and function. Damage to this layer is indicative of vascular injury, reflected by increased levels of its shed constituents in serum and an increase in the perfused boundary region (PBR) when measured in sublingual capillaries using the GlycoCheck™ device. We aimed to examine the longitudinal effects of kidney transplantation on the glycocalyx by measuring biochemical markers of the glycocal...
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#1Jingjing Wu (PRC: China Medical University (PRC))H-Index: 5
#2Guangrui Lai (PRC: China Medical University (PRC))H-Index: 5
Last. Yanyan Zhao (PRC: China Medical University (PRC))H-Index: 11
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INTRODUCTION 20-Hydroxyeicosatetraenoic acid (20-HETE) is the metabolite of cytochrome P450, which modulates blood pressure by inhibiting renal sodium transport. However, the molecular mechanisms underlying the role of 20-HETE in the development of obesity-related hypertension remain unclear, necessitating this study. METHODS Cytochrome P450 4F2 (CYP4F2) transgenic mice fed high-fat diet (HFD) were used as research animal models. The expression of renal ion transport molecules targeted by 20-HET...
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#1Jonathan S Chávez-Iñiguez (University of Guadalajara)H-Index: 5
#2Pablo Maggiani-Aguilera (University of Guadalajara)H-Index: 1
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Background null Based on the pathophysiology of acute kidney injury (AKI), it is plausible that certain early interventions by the nephrologist could influence its trajectory. In this study, we investigated the impact of 5 early nephrology interventions on starting kidney replacement therapy (KRT), AKI progression, and death. null Methods null In a prospective cohort at the Hospital Civil of Guadalajara, we followed up for 10 days AKI patients in whom a nephrology consultation was requested. We ...
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#1Hormat Rahimzadeh (Tehran University of Medical Sciences)H-Index: 1
#2Sina Kazemian (Tehran University of Medical Sciences)H-Index: 2
Last. Atefeh Jannatalipour (Tehran University of Medical Sciences)
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INTRODUCTION: Kidney involvement, ranging from mild hematuria and proteinuria to acute kidney injury (AKI) in patients with coronavirus disease-2019 (COVID-19), is a recent finding with various incidence rates reported among hospitalized patients with COVID-19. Given the various AKI rates and their associated risk factors, lack of AKI recovery in the majority of patients hospitalized with COVID-19, and limited data regarding AKI in patients with COVID-19 in Iran, we aim to investigate the potent...
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#1Guoliang Zheng (UQ: University of Queensland)
#2Swetha R KanduriH-Index: 5
Last. Juan Carlos Q. Velez (UQ: University of Queensland)H-Index: 22
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Introduction null Oncogenic osteomalacia (Onc-Ost) is a paraneoplastic phenomenon characterized by hypophosphatemia due to elevated fibroblast growth factor-23 (FGF-23). Onc-Ost has been previously reported in patients with germ line mesenchymal tumors and solid organ malignancies. This is the first report of aggressive natural killer (NK) T-cell lymphoma presenting as Onc-Ost. null Case description null A 33-year-old Vietnamese female with active hepatitis B and Mycobacterium avium complex, on ...
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#1Gamze Aytaş (Bezmialem Foundation University)
#2Rumeyza Kazancioglu (Bezmialem Foundation University)H-Index: 22
Last. Semra Özçelik (Bezmialem Foundation University)H-Index: 13
view all 9 authors...
Introduction null Orthostatic hypotension (OH) affects 5-20% of the population. Our study investigates the presence of OH in diabetic nephropathy (DNP) patients and the factors affecting OH in comparison with nondiabetic chronic kidney disease (NDCKD) patients. null Method null Patients presented to the nephrology clinic, and those who consented were included in the study. DNP was defined by kidney biopsy and/or clinical criteria. NDCKD patients of the same sex, age, and eGFR were matched to DNP...
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Top fields of study
Endocrinology
Renal function
Chemistry
Kidney
Diabetes mellitus
Medicine