Pediatric Research
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#1Sripriya Sundararajan (UMB: University of Maryland, Baltimore)H-Index: 3
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#1Jennifer Jao (NU: Northwestern University)H-Index: 3
#2Lauren C. Balmert (NU: Northwestern University)H-Index: 8
Last. Stephen Arpadi (UCT: University of Cape Town)
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BACKGROUND Early-life metabolic derangements in HIV-exposed uninfected (HEU) infants have been reported. METHODS Pregnant women with HIV and HIV-uninfected pregnant women were enrolled with their newborns in a US cohort from 2011 to 2015. We measured cord insulin, C-peptide, and metabolic cytokines of HEU and HIV-unexposed uninfected (HUU) newborns using ELISA and metabolites, lipid subspecies, and eicosanoids via liquid chromatography/mass spectrometry. Linear regression was employed to assess ...
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#1Astrid Nieuwets (UU: Utrecht University)H-Index: 2
#2Mehmet N. Cizmeci (UU: Utrecht University)
Last. Niek E. van der Aa (UU: Utrecht University)H-Index: 12
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BACKGROUND Data on microstructural white matter integrity in preterm infants with post-hemorrhagic ventricular dilatation (PHVD) using diffusion tensor imaging (DTI) are limited. Also, to date, no study has focused on the DTI changes in extremely preterm (EP) infants with PHVD. METHODS A case-control study of EP infants <28 weeks' gestation with PHVD was conducted. Diffusivity and fractional anisotropy (FA) values of corticospinal tracts (CST) and corpus callosum (CC) were measured using DTI at ...
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#1Wafaa moustafa M. Abo El-fotoh (Menoufia University)H-Index: 2
#2Hebatallah Mohammed Nasser Bahbah (Menoufia University)
Last. Noha Rabie Bayomy (Menoufia University)H-Index: 2
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Backround null This study aimed to assess the possible association between rs41423247 (Bcl-I) polymorphism in the gene for the human glucocorticoid receptor (GR) called Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1) with obesity in Egyptian children with and without Down syndrome. null Methods null The Bcl-I polymorphism was assessed, using real-time PCR, in 300 children divided into four groups: Down-obese, Down-non obese, normal-obese, and normal non-obese. null Results null There was n...
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#1Ibrahim Qattea (MetroHealth)H-Index: 1
#2Mohsen A. A. Farghaly (MetroHealth)
Last. Hany Aly (Cleveland Clinic)H-Index: 5
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OBJECTIVE The objective of this study was to assess the prevalence and trends for neonatal hyperbilirubinemia, and the development of bilirubin neurotoxicity in the USA. STUDY DESIGN We used a de-identified national dataset for the years 2002-2017. The study included all newborn inpatients with postnatal age ≤28 days. Cochran-Armitage trend test was used for trend analyses. Regression analyses were performed and adjusted odds ratios (aOR) were reported. RESULTS The study included 57,989,476 infa...
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#1Aryaz Sheybani (Boston Children's Hospital)
#2Kim Crum (Boston Children's Hospital)
Last. Jonathan H. Soslow (Boston Children's Hospital)H-Index: 10
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Background null Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD), but studies suggest heart failure biomarkers correlate poorly with cardiomyopathy severity. DMD clinical trials have used troponin I (cTnI) as a biomarker of toxicity, but it is unclear if asymptomatic DMD patients have elevated cTnI. We longitudinally evaluated cTnI, brain natriuretic peptide (BNP), and N-terminal pro-BNP (NT-proBNP) in a DMD cohort. null Methods null DMD patients were prospective...
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#1Julia Suikkanen (National Institute for Health and Welfare)H-Index: 1
#1Julia Suikkanen (National Institute for Health and Welfare)
Last. Eero Kajantie (National Institute for Health and Welfare)H-Index: 88
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BACKGROUND We evaluated pubertal growth and pubertal timing of participants born preterm compared to those born at term. METHODS In the ESTER Preterm Birth Study, we collected growth data and measured final height of men/women born very or moderately preterm (<34 gestational weeks, n = 52/55), late preterm (34-<37 weeks, 94/106), and term (≥37 weeks, 131/151), resulting in median 9 measurements at ≥6 years. Timing of menarche or voice break was self-reported. Peak height velocity (PHV, cm/year) ...
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#1Gunilla Önning (Lund University)H-Index: 27
Last. Niklas Larsson (Lund University)H-Index: 8
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Background null Different microorganisms from the environment will begin to colonise the infant during and immediately after the delivery. It could be advantageous to influence the microbiome early on by giving infants probiotic bacteria. The aim of the study was to investigate the tolerance of two probiotic lactobacilli in infants. The effect on the microbiota was also followed. null Methods null Thirty-six healthy infants, aged 4-83 days at the start of the study, were given a daily supplement...
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#1Christian Nguyen (VUMC: Vanderbilt University Medical Center)
#2Shari L. Barkin (VUMC: Vanderbilt University Medical Center)H-Index: 29
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#1Mads Langager Larsen (Copenhagen University Hospital)H-Index: 1
#2Rikke WiingreenH-Index: 2
Last. Gorm Greisen (Copenhagen University Hospital)H-Index: 72
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BACKGROUND Preterm infants have an increased risk of neurodevelopmental disorders. We established a direct quantitative comparison of the association between the degree of prematurity and three different neurodevelopmental disorders. METHODS In this cohort study, we combined data from 995,498 children in the Danish Medical Birth Register, from birth years 1997-2013, with information on cerebral palsy, epilepsy, and special educational needs. We estimated the gestational week-specific prevalence ...
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