#2Xiaolin Xu(Capital Medical University)H-Index: 10
Last. Wenbin Wei(Capital Medical University)H-Index: 9
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PURPOSE Primary central nervous system lymphoma (PCNSL) is a non-Hodgkin lymphoma involving the brain with possible leptomeningeal and ocular involvement. This study aimed to evaluate the safety and efficacy of modified intravitreal injection regimen of methotrexate (MTX) for therapeutic management of vitreoretinal lymphoma. MATERIALS AND METHODS Forty human immunodeficiency virus (HIV)-negative Chinese patients with primary vitreoretinal lymphoma were included in this retrospective noncomparati...
OBJECTIVES To present and validate a deep ensemble algorithm to detect diabetic retinopathy (DR) and diabetic macular oedema (DMO) using retinal fundus images. METHODS A total of 8739 retinal fundus images were collected from a retrospective cohort of 3285 patients. For detecting DR and DMO, a multiple improved Inception-v4 ensembling approach was developed. We measured the algorithm's performance and made a comparison with that of human experts on our primary dataset, while its generalization w...
PURPOSE To evaluate the 12-month outcomes of a novel posterior small incision sub-tenon ab interno technique of XEN stent insertion ('Semi-open'). METHOD Consecutive eyes underwent XEN stent insertion with the Semi-open technique by two surgeons between 1st July 2018 and 30th September 2019. All cases received subconjunctival injection of 0.1 mL of mitomycin C 0.2 mg/mL. Eyes with primary open angle glaucoma (OAG), secondary OAG or pseudophakic primary angle closure glaucoma (PACG) were included...
INTRODUCTION As gonococcal infections continue to increase, we wanted to review the number and clinical course of recent ocular gonococcal cases presenting to ophthalmology departments in NHS Greater Glasgow and Clyde. METHODS A 5-year retrospective review of adult ocular gonococcal cases, where the diagnosis of Neisseria gonorrhoeae was made on microbiological culture, was undertaken. RESULTS Fifteen cases were identified (80% male). Average age was 26 years (range 17-42; median 24). Most commo...
Last. Petros Petrou(UoA: National and Kapodistrian University of Athens)H-Index: 13
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BACKGROUND To assess the association between optical coherence tomography angiography (OCTA) retinal measurements and Alzheimer's disease (AD). METHODS We searched MEDLINE and EMBASE from inception up to October 28th, 2020 for studies assessing the association between OCTA retinal measurements and AD. Estimates from eligible studies were meta-analysed and pooled standardized mean differences (SMDs) between AD patients and healthy participants with corresponding 95% confidence intervals (95% CI) ...
OBJECTIVES: To evaluate the effect of the COVID-19 pandemic restrictions on myopia progression (MP) in school age children. METHODS: A total of 115 children aged 8-17 years with a diagnosis of myopia who had been followed-up for at least three years, were included in this study with a retrospective and single-centre design. The subjects' age, the history of myopia in the family, the time spent in front of a screen, the digital devices used during home education (computer, tablet, smartphone, tel...