Cell Transplantation
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#1Lauren M Timmins (RU: Rutgers University)H-Index: 1
#2Alexandra Burr (RU: Rutgers University)H-Index: 1
Last. Biju Parekkadan (RU: Rutgers University)H-Index: 23
view all 11 authors...
When considering the development pathway for a genetically modified cell therapy product, it is critically important that the product is engineered consistent with its intended human use. For scientists looking to develop and commercialize a new technology, the decision to select a genetic modification method depends on several practical considerations. Whichever path is chosen, the developer must understand the key risks and potential mitigations of the cell engineering approach. The developer ...
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#1Shunli Rui (CQMU: Chongqing Medical University)
#2Yi Yuan (Chongqing University)H-Index: 2
Last. Ling Li (CQMU: Chongqing Medical University)H-Index: 27
view all 10 authors...
PRP-Exos are nanoscale cup-shaped vesicles that carry a variety of proteins, mRNAs, microRNAs, and other bioactive substances. PRP-Exos can be formed through several induction pathways, which deter...
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#1Gulce Sari (Erasmus University Medical Center)H-Index: 4
#2Gertine W. van Oord (Erasmus University Medical Center)H-Index: 11
Last. Thomas Vanwolleghem (Erasmus University Medical Center)H-Index: 16
view all 6 authors...
Humanized liver mouse models are crucial tools in liver research, specifically in the fields of liver cell biology, viral hepatitis and drug metabolism. The livers of these humanized mouse models a...
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#1Piotr J. Bachul (U of C: University of Chicago)H-Index: 6
#2Karolina Golab (U of C: University of Chicago)H-Index: 7
Last. Piotr Witkowski (U of C: University of Chicago)H-Index: 28
view all 22 authors...
A recent randomized, multicenter trial did not show benefit of a CXCR1/2 receptor inhibitor (Reparixin) when analysis included marginal islet mass (>3,000 IEQ/kg) for allotransplantation and when i...
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#1Srividya Vasu (Baylor University Medical Center)
#1Srividya Vasu (Baylor University Medical Center)H-Index: 2
Last. Melena D. Bellin (UMN: University of Minnesota)H-Index: 40
view all 24 authors...
Circulating microRNAs (miRNAs) can be biomarkers for diagnosis and progression of several pathophysiological conditions. In a cohort undergoing total pancreatectomy with islet autotransplantation (...
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#1Er-Hu Wei (Zhengzhou University)H-Index: 1
#2Xiao Fang (Zhengzhou University)
Last. Dan Gao (Zhengzhou University)
view all 8 authors...
Pneumonia is a serious respiratory tract infection disease in children, which threatens to the health or life of children patients. Ginsenoside Rb1 (Rb1) is a principle active ingredient extracted from the root of Panax notoginseng (Burk.) F.H. Chen with anti-inflammatory effect. Our study aimed to determine the effects and molecular mechanisms of Rb1 on lipopolysaccharide (LPS)-induced inflammatory injury of lung fibroblasts WI-38 cells. Cell viability and apoptosis were evaluated by CCK-8 and ...
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#1Chenxia Ren (Changzhi Medical College)
#2Cuiling Wu (Changzhi Medical College)
Last. Changqing Yang (Changzhi Medical College)
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Stomach adenocarcinoma (STAD) is a highly heterogeneous disease. Due to the lack of effective molecular markers and personalized treatment, the prognosis of gastric cancer patients is still very poor. The ABSOLUTE algorithm and cancer cell fraction were used to evaluate the clonal and subclonal status of 349 TCGA (The Cancer Genome Cancer Atlas)-STAD patients. Non-negative matrix factorization was used to identify the mutation characteristics of the samples. Univariate Cox regression analysis wa...
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#1Kazuaki Shibuya (Hokkaido University)H-Index: 4
#2Masaaki Watanabe (Hokkaido University)H-Index: 9
Last. Akinobu Taketomi (Hokkaido University)H-Index: 66
view all 6 authors...
The safety and short-term efficacy of hepatocyte transplantation (HCTx) have been widely proven. However, issues such as reduced viability and/or function of hepatocytes, insufficient engraftment, and lack of a long-term effect have to be overcome for widespread application of HCTx. In this study, we evaluated hepatocyte spheroids (HSs), formed by self-aggregation of hepatocytes, as an alternative to hepatocytes in single-cell suspension. Hepatocytes were isolated from C57BL/6 J mice liver using...
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#1Ning Wang (Xi'an Jiaotong University)H-Index: 8
#2Qian Song (Xi'an Jiaotong University)
Last. Gang Bao (Xi'an Jiaotong University)
view all 4 authors...
FBXO17 is a newly studied F-box protein associated with high-grade glioma. However, its exact role in glioma remains unclear. In the present study, we aimed to investigate the role of FBXO17 in gli...
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#1Hong-Meng ChuangH-Index: 3
#2Li-Ing Ho (Taipei Veterans General Hospital)H-Index: 1
Last. Ching-Ann LiuH-Index: 1
view all 4 authors...
COVID-19 has spread worldwide, including the United States, United Kingdom, and Italy, along with its site of origin in China, since 2020. The virus was first found in the Wuhan seafood market at the end of 2019, with a controversial source. The clinical symptoms of COVID-19 include fever, cough, and respiratory tract inflammation, with some severe patients developing an acute and chronic lung injury, such as acute respiratory distress syndrome (ARDS) and pulmonary fibrosis (PF). It has already ...
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Top fields of study
Islet
Immunology
Stem cell
Transplantation
Diabetes mellitus
Medicine
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