Nuklearmedizin-nuclear Medicine
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1.38
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2,240
Papers 2,323
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#1Daniel Schmidt (University Hospital Regensburg)
#2Jirka Grosse (University Hospital Regensburg)H-Index: 24
Last. Dirk Hellwig (University Hospital Regensburg)H-Index: 33
view all 5 authors...
Aim [99mTc]Tc-PSMA-based radioguided surgery (TPRS) represents a curative approach for localized relapse of prostate cancer. For its simplified regulatory permission, the radiation protection authorities require a 99mTc- activity below the exemption limit of 10 MBq at the time of surgery. Our aim was to determine the optimal amount of radioactivity (OAR) to comply with that limit and to estimate the maximum number of TPRS procedures per year and surgeon without triggering the full monitoring obl...
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#1Soo Bin Park (Soonchunhyang University Hospital)H-Index: 2
#2Chae Hong Lim (Soonchunhyang University Hospital)
Last. Jung Mi Park (Soonchunhyang University Hospital)
view all 7 authors...
Purpose We investigated the diagnostic performance of single photon emission computed tomography (SPECT)/computed tomography (CT) as a combination of functional and anatomic imaging, in patients with unspecified chest wall pain. null null null null Methods Fifty-two patients with unspecified chest wall pain and no history of recent major traumatic events or cardiac disease were included. The number and location of radioactive chest wall lesions were evaluated on both planar images and SPECT/CT. ...
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#1Willm Uwe KampenH-Index: 9
#2Lutz S. FreudenbergH-Index: 37
Last. R. KlettH-Index: 9
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Die popliteale Bakerzyste galt lange Zeit als Kontraindikation bei der Durchfuhrung einer Radiosynoviorthese (RSO). Insbesondere bei einem vorliegenden „Ventilmechanismus“ der Zyste furchtete man eine vermehrte Anreicherung des intraartikular injizierten Radiopharmazeutikums Yttrium-90-Kolloid in der Zyste, die aus einer mit der Kniegelenkhohle kommunizierenden Bursa unter dem medialen Kopf des M. gastrocnemius bei chronischer Arthritis mit Ergussneigung entstehen kann. Aufgrund der im Vergleich...
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#1Renata Koukalová (Masaryk University)H-Index: 8
#2Jiří Vašina (Masaryk University)H-Index: 2
Last. Petr Szturz (UNIL: University of Lausanne)H-Index: 14
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Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An 18F-FDG PET/CT revealed an overall ...
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Die Theranostik uber den Natrium-Iodid-Symporter (NIS) bietet bei differenzierten Schilddrusenkarzinomen eine einzigartige Option. Die diagnostischen und therapeutischen Nuklide weisen eine ubereinstimmende Aufnahme und Kinetik auf, sodass der NIS das wichtigste theranostische Target bei dieser Erkrankung darstellt. Radioiodrefraktare Schilddrusenkarzinome (RRTC) zeichnen sich durch eine verminderte/fehlende NIS-Expression aus, sodass diese Struktur als theranostisches Ziel entfallt. Auch aufgru...
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Theranostic applications with radio-isotopes currently are rapidly progressing and expand nuclear medicine application in clinical routine. Alpha emitting isotopes, in particular, have long been hypothesized to achieve relevant advances for the treatment of malignancies. Here, an overview of their properties and the knowledge of radiobiology is reviewed in view of clinical translation. Clinical evidence of radiopharmaceuticals based on alpha emitters is summarized with a focus on recent developm...
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#1Wolfgang Burchert (RUB: Ruhr University Bochum)H-Index: 24
#2Jörg van den HoffH-Index: 8
Last. Lilli GeworskiH-Index: 15
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#1Sheima Farag (NKI-AVL: Netherlands Cancer Institute)
#2Nikki S IJzerman (NKI-AVL: Netherlands Cancer Institute)H-Index: 4
Last. Lioe-Fee de Geus-Oei (LUMC: Leiden University Medical Center)H-Index: 29
view all 10 authors...
Aim The aim of this study was to investigate the impact of 18F-FDG-PET/CT on treatment decision making in metastatic gastrointestinal stromal tumor (GIST) patients. null null null null Methods This study retrospectively evaluated 18F-FDG-PET/CT scans to monitor response of metastatic GIST patients treated with palliative intent. Data from the Dutch GIST Registry was used. Early scans ( 10 weeks after start of treatment) were scored on the impact in change of treatment. null null null null Result...
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