Epidemiology
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#1Covello L (UM: University of Michigan)
#2Andrew Gelman (Columbia University)H-Index: 118
Last. Wang S (Columbia University)
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Throughout the coronavirus disease 2019 (COVID-19) pandemic, government policy and healthcare implementation responses have been guided by reported positivity rates and counts of positive cases in the community. The selection bias of these data calls into question their validity as measures of the actual viral incidence in the community and as predictors of clinical burden. In the absence of any successful public or academic campaign for comprehensive or random testing, we have developed a proxy...
2 CitationsSource
#1Etsuji Suzuki (Okayama University)H-Index: 26
#2Eiji Yamamoto (Okayama University of Science)H-Index: 14
For decades, the sufficient cause model and the counterfactual model have shaped our understanding of causation in biomedical science, and the link between these two models has enabled us to obtain a deeper understanding of causality. Recently, a new causal model-the marginal sufficient component cause model-was proposed and applied in the context of interaction or mediation. The proponents of this model have emphasized its utility in visualizing the presence of "agonism" (a subtype of mechanist...
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#1Timo E Strandberg (Finnish Institute of Occupational Health)
#2Jaana Pentti (Finnish Institute of Occupational Health)H-Index: 74
Last. Mika Kivimäki (Finnish Institute of Occupational Health)H-Index: 182
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#1Michael D George (UAB: University of Alabama at Birmingham)
#2Jesse Y. HsuH-Index: 17
Last. Joshua F. BakerH-Index: 29
view all 7 authors...
Background null Low-dose glucocorticoids are commonly used in the treatment of rheumatoid arthritis (RA). Observational studies have found increased risk of serious infection associated with low-dose glucocorticoids, but concerns about residual confounding remain. null Methods null We identified adults with RA on stable immunomodulatory therapy for >6 months receiving no glucocorticoids or ≤5mg/day using Medicare data from 2006-2015. We used provider preference for glucocorticoids as an instrume...
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#1Jung In Kim (UNC: University of North Carolina at Chapel Hill)H-Index: 3
Last. Shanshan ZhaoH-Index: 21
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Background null Preinvasive cancer conditions are often actively treated to minimize progression to life-threatening invasive cancers, but this creates challenges for analysis of invasive cancer risk. Conventional methods of treating preinvasive conditions as censoring events or targeting at the composite outcome could both lead to bias. null Methods null We propose two solutions: one that provides exact estimates of risk based on distributional assumptions about progression, and one that provid...
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#1Nikos StratakisH-Index: 7
#2Erika GarciaH-Index: 9
Last. Carlos A. CamargoH-Index: 147
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Rationale null Asthma and obesity often co-occur. It has been hypothesized that asthma may contribute to childhood obesity onset. null Objectives null To determine if childhood asthma is associated with incident obesity and examine the role of asthma medication in this association. null Methods null We studied 8716 children between ages 6-18.5 years who were non-obese at study entry participating in 18 U.S. cohorts of the Environmental influences on Child Health Outcomes program (among 7299 chil...
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#1Michael J. Lopez (UNC: University of North Carolina at Chapel Hill)
#2Christina D. MackH-Index: 12
Last. Dan HanflingH-Index: 21
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BACKGROUND: The National Football League (NFL) and National Football League Players Association (NFLPA) implemented a set of strict protocols for the 2020 season with the intent to mitigate COVID-19 risk among players and staff. In that timeframe, the league's 32 teams completed 256 regular season games and several thousand meetings and practices. In parallel, community cases of COVID-19 were highly prevalent. We assess the risk of holding a 2020 NFL season by comparing community and player COVI...
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#1Teresa J. Filshtein (UCSF: University of California, San Francisco)H-Index: 7
#2Xiang Li (GW: George Washington University)
Last. Melinda C. Power (GW: George Washington University)H-Index: 27
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BACKGROUND Integrating results from multiple samples is often desirable, but privacy restrictions may preclude full data pooling, and most datasets do not include fully harmonized variable sets. We propose a simulation-based method leveraging partial information across datasets to guide creation of synthetic data, based on explicit assumptions about the underlying causal structure, that permits pooled analyses that adjust for all desired confounders in the context of privacy restrictions. METHOD...
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#1Michail Katsoulis (UCL: University College London)H-Index: 22
#2Bianca De Stavola (ICH: UCL Institute of Child Health)H-Index: 39
Last. Spiros DenaxasH-Index: 31
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BACKGROUND Cross-sectional measures of body mass index (BMI) are associated with cardiovascular disease (CVD) incidence, but less is known about whether weight change affects the risk of CVD. METHODS We estimated the effect of 2-y weight change interventions on 7-y risk of CVD (CVD death, myocardial infarction, stroke, hospitalization from coronary heart disease, and heart failure) by emulating hypothetical interventions using electronic health records. We identified 138,567 individuals with 45-...
1 CitationsSource
#1Motao Zhu (Nationwide Children's Hospital)H-Index: 19
#2Sijun Shen (Nationwide Children's Hospital)H-Index: 2
Last. Robert D. Foss (UNC: University of North Carolina at Chapel Hill)H-Index: 25
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Background null As of January 2020, 18 of 50 US states comprehensively banned almost all handheld cellphone use while driving, 3 states and the District of Columbia banned calling and texting, 27 states banned texting on a handheld cellphone, and 2 states had no general cellphone ban for all drivers. However, it remains unknown whether these bans were associated with fewer traffic deaths and whether comprehensive handheld bans are more effective than isolated calling or texting bans. We evaluate...
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