Journal of Breast Cancer
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#2Cristina GutierrezH-Index: 34
Last. Vratislav Strnad (FAU: University of Erlangen-Nuremberg)H-Index: 30
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#1Sayantan Banik (SRM University)
#2Sudeshna Rakshit (SRM University)
Last. Koustav Sarkar (SRM University)H-Index: 16
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Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that facilitate several facets of cellular immunity, proliferation, apoptosis, and differentiation. They are principally stimulated by membrane receptor-associated Janus kinases. Dysregulation of this pathway is often detected in primary tumors and hints at augmented angiogenesis, which enriches tumors persistence and immunosuppression. STAT proteins play indispensable ro...
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#1Weipeng Liu (CTGU: China Three Gorges University)
#2Xin Zhou (CTGU: China Three Gorges University)
Last. Aijun Chen (CTGU: China Three Gorges University)
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PURPOSE Non-coding RNA activated by DNA damage (NORAD) has been reported to be a cancer-related long non-coding RNA (lncRNA) implicated in the progression of several cancers; however, its role in breast cancer (BC) has not yet been clarified. METHODS Quantitative real-time polymerase chain reaction was used to examine NORAD, microRNA (miR)-155-5p, and suppressor of cytokine signaling 1 (SOCS1) mRNA expression levels. Western blotting was used to analyze SOCS1 protein expression. The malignancy o...
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#1Jong Ho Cheun (New Generation University College)
#2Jiyoung Won (Seoul National University Hospital)
Last. Han Byoel Lee (New Generation University College)H-Index: 10
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Purpose null Trastuzumab is effective in early and advanced human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, few studies have reported the effect of trastuzumab on ipsilateral breast tumor recurrence (IBTR), whose incidence is higher in the HER2-positive subtype than in other subtypes. null Methods null We retrospectively investigated 959 patients who underwent breast-conserving surgery (BCS), chemotherapy, and radiotherapy for HER2-positive breast cancer between ...
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Purpose null The programmed death ligand 1 (PD-L1) SP142 assay with a 1% immune cell (IC) cutoff is approved for the selection of advanced triple-negative breast cancer (TNBC) patients for atezolizumab treatment. We aimed to evaluate the interobserver concordance of PD-L1 scoring and inter-assay variability of various PD-L1 assays in TNBC. null Methods null Thirty patients with primary TNBC were selected, and SP142, SP263, 22C3, and E1L3N assays were performed. PD-L1 staining in ICs and tumor ce...
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#1Jihyoun Lee (SCH: Soonchunhyang University)H-Index: 12
#2Ji Sung Lee (UOU: University of Ulsan)
Last. Sungmin Park (CBNU: Chungbuk National University)H-Index: 8
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#1Marta Bottero (University of Rome Tor Vergata)H-Index: 5
#2V. BorzilloH-Index: 5
Last. Rolando Maria D'Angelillo (University of Rome Tor Vergata)H-Index: 20
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#1Jae-Ho Chung (Korea University Medical Center)H-Index: 3
#2Yong-Jae Hwang (Korea University Medical Center)
Last. Eul Sik Yoon (Korea University Medical Center)H-Index: 19
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#1Chenguang Zhang (XMU: Xinjiang Medical University)
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#1Haeyoung Kim (SMC: Samsung Medical Center)H-Index: 10
#2Danbee Kang (SMC: Samsung Medical Center)H-Index: 15
Last. Kyeong Tae Lee (SMC: Samsung Medical Center)H-Index: 4
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PURPOSE In this study, we examined the impact of reconstruction using tissue expander insertion (TEI) on the risk of radiation dermatitis in patients undergoing postmastectomy radiotherapy (PMRT). METHODS Between August 2015 and March 2019, patients with breast cancer who had received systemic chemotherapy and PMRT were prospectively included. Skin parameters, including melanin, erythema, hydration, sebum, and elasticity, were measured using a multi-probe instrument at 6 time points: before the ...
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Cancer
Pathology
Oncology
Breast cancer
General surgery
Medicine