Journal of Breast Cancer
Papers 968
1 page of 97 pages (968 results)
#1Jung Min Chang (SNUH: Seoul National University Hospital)H-Index: 33
#2Hee Jung Shin (AMC : Asan Medical Center)H-Index: 24
Last. Woo Kyung Moon (SNUH: Seoul National University Hospital)H-Index: 60
view all 12 authors...
#1Fernando Osório (University of Porto)H-Index: 1
#2António BarrosH-Index: 1
Last. Adelino F. Leite-MoreiraH-Index: 45
view all 7 authors...
#1Hyelim Kim (SNUH: Seoul National University Hospital)H-Index: 1
#2Woo Kyung Moon (SNUH: Seoul National University Hospital)H-Index: 60
PURPOSE The breast cancer susceptibility gene, BRCA1, is involved in normal development and carcinogenesis of mammary glands. Here, we aimed to evaluate the relationship between histological findings of mammary gland development and breast cancer risk in BRCA1 mutant mice. METHODS Five BRCA1 mutant mice and five non-mutant FVB/NJ mice were used for each group of 1-month-old (pubertal), 3-month-old (fertile), and 8-month-old (menopausal) mice. In another experiment, 15 BRCA1 mutant mice were foll...
#1Masahiro Takeuchi (University of Occupational and Environmental Health Japan)H-Index: 35
#2Takefumi Katsuki (University of Occupational and Environmental Health Japan)H-Index: 10
Last. Keiji Hirata (University of Occupational and Environmental Health Japan)H-Index: 20
view all 10 authors...
Locally advanced breast cancer (tumor > 5 cm, widespread infiltration of the skin and muscle, or metastases to lymph nodes) is difficult to resect by surgery, and even when it is resectable, there is a high probability of local recurrence and distant metastasis. Therefore, systemic therapy should be administered first. However, as cutaneous infiltration progresses, the patient's quality of life is impaired by pain, bleeding, presence of exudates, and a foul-smelling odor. Treatment with Mohs pas...
#1Kwang-Min Kim (Yonsei University)
#2Hyang Suk Choi (Yonsei University)
Last. Airi Han (Yonsei University)H-Index: 4
view all 7 authors...
PURPOSE Triple-negative breast cancer (TNBC) has been associated with worse prognosis, and biomarkers are needed to identify high-risk patients who may benefit from clinical trials or escalated treatment after completion of standard treatment. We aimed to assess whether the post-treatment neutrophil-to-lymphocyte ratio (NLR) can reflect patient prognosis and determine the follow-up period that can provide the most feasible data. METHODS In this retrospective analysis involving patients with TNBC...
#1Liqiang Qi (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 3
#2Bo Sun (TMUCIH: Tianjin Medical University Cancer Institute and Hospital)H-Index: 2
Last. Su Lu (TMUCIH: Tianjin Medical University Cancer Institute and Hospital)H-Index: 1
view all 4 authors...
Purpose null Triple-negative breast cancer (TNBC) is a subtype of breast cancer. Increasing evidence supports that dysregulation of long noncoding RNAs (lncRNAs) plays a vital role in cancer progression. RNA component of mitochondrial RNA processing endoribonuclease (RMRP), a lncRNA, is characterized as a tumor-propeller in some cancers, but its mechanism in TNBC remains poorly understood. This study aimed to determine whether and how RMRP functions in TNBC. null Methods null Cell proliferation ...
#1Kartika Widayati Taroeno-Hariadi (UGM: Gadjah Mada University)H-Index: 2
#2Yasjudan Rastrama Putra (UGM: Gadjah Mada University)
Last. Teguh Aryandono (UGM: Gadjah Mada University)H-Index: 14
view all 6 authors...
PURPOSE Long-term estrogen inhibition may cause fatty liver disease (non-alcoholic fatty liver disease; NAFLD) among other adverse conditions such as osteoporosis, climacteric symptoms, thromboembolism, dyslipidemia, and metabolic syndrome. The prevalence of NAFLD among breast cancer patients ranges from 2.3%-45.2%. This study aimed to determine the risk factors for newly developed NAFLD among breast cancer patients after hormonal treatment and whether it influences survival outcomes. METHODS Th...
#1Jiani Pan (ZJNU: Zhejiang Chinese Medical University)H-Index: 1
#2Lei Lei (CAS: Chinese Academy of Sciences)H-Index: 4
Last. Wen-Ming Cao (CAS: Chinese Academy of Sciences)H-Index: 12
view all 5 authors...
Reversion mutations are associated with clinical resistance to poly(ADP-ribose) polymerase inhibitors (PARPi). Here, we describe the detection of a BRCA1 reversion mutation in a 39-year-old woman with metastatic breast cancer harboring a heterozygous germline BRCA1 exons 7-8 deletion who received PARPi olaparib combined with immune checkpoint inhibitor camrelizumab as third-line therapy. During progression from the olaparib and camrelizumab combination therapy, we identified via genomic sequenci...
#1Inwon Park (NGUC: New Generation University College)H-Index: 9
#2Sujung Hong (KAIST: Korea Advanced Institute of Science and Technology)H-Index: 3
Last. Soyeon Ahn (KAIST: Korea Advanced Institute of Science and Technology)H-Index: 6
view all 16 authors...
Immunoreactive dynamics of tumor-infiltrating lymphocytes (TILs) within the tumor microenvironment in breast cancer are not well understood. This study aimed to investigate the spatiotemporal cellular dynamics of TILs in breast cancer models. Breast cancer cells were implanted into the dorsal skinfold chamber of BALB/c nude mice, and T lymphocytes were adoptively transferred. Longitudinal intravital imaging was performed, and the spatiotemporal dynamics of TILs were assessed. In the 4T1 model, T...
view all 6 authors...
Purpose null The purpose of the current study was to explore the functions and potential mechanism of miR-451a in breast cancer (BC). null Methods null Quantitative reverse transcription real-time polymerase chain reaction was used to analyze the expression of miR-451a in human normal mammary cells (MCF-10A) and BC cells. Colony formation assay, terminal-deoxynucleoitidyl transferase mediated nick end labeling assay and transwell assays were conducted to validate the effect of miR-451a on prolif...
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