Seminars in Neurology
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#1Leana Doherty (University of Pittsburgh)
#2Vinay Chaudhry (UNC: University of North Carolina at Chapel Hill)
Although many neuromuscular conditions are evaluated on an outpatient basis owing to their chronic or progressive nature, more urgent evaluation and management is often required for the inpatient presenting with acute to subacute focal or generalized numbness or weakness. This review focuses on clinical pattern recognition and basic anatomic localization principles to aid in the identification of common, as well as some less frequently encountered, neuromuscular disorders in hospitalized patient...
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#1Abrar O Al-Faraj (BU: Boston University)H-Index: 2
#2Myriam Abdennadher (BU: Boston University)H-Index: 5
Last. Trudy Pang (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 10
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Seizures are among the most common neurological presentations to the emergency room. They present on a spectrum of severity from isolated new-onset seizures to acute repetitive seizures and, in severe cases, status epilepticus. The latter is the most serious, as it is associated with high morbidity and mortality. Prompt recognition and treatment of both seizure activity and associated acute systemic complications are essential to improve the overall outcome of these patients. The purpose of this...
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#1Kristin M. Galetta (Brigham and Women's Hospital)H-Index: 21
#2Shamik Bhattacharyya (Brigham and Women's Hospital)H-Index: 12
Systemic autoimmune diseases can affect the peripheral and central nervous system. In this review, we outline the common inpatient consultations for patients with neurological symptoms from rheumatoid arthritis, Sjogren's syndrome, systemic lupus erythematosus, sarcoidosis, immunoglobulin G4-related disease, Behcet's disease, giant cell arteritis, granulomatosis with polyangiitis, microscopic polyangiitis, eosinophilic granulomatosis, polyarteritis nodosa, and ankylosing spondylitis. We discuss ...
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#1Adeline L. Goss (UCSF: University of California, San Francisco)H-Index: 3
#2Claire J. Creutzfeldt (UW: University of Washington)H-Index: 20
The palliative care needs of inpatients with neurologic illness are varied, depending on diagnosis, acuity of illness, available treatment options, prognosis, and goals of care. Inpatient neurologists ought to be proficient at providing primary palliative care and effective at determining when palliative care consultants are needed. In the acute setting, palliative care should be integrated with lifesaving treatments using a framework of determining goals of care, thoughtfully prognosticating, a...
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#1Myriam Abdennadher (BU: Boston University)H-Index: 5
#2Aneeta Saxena (BU: Boston University)H-Index: 3
Last. Milena Pavlova (Brigham and Women's Hospital)H-Index: 39
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First seizures are often perceived as devastating events by patients and their families due to the fear of having a life-long disease. One in 10 people experiences one or more seizures during their lifetime, while 1 in 26 people develops epilepsy. Acute symptomatic seizures are often related to a provoking factor or an acute brain insult and typically do not recur. Careful history and clinical examination should guide clinicians' management plans. Electroencephalography and brain imaging, prefer...
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#1Elia Sechi (Mayo Clinic)H-Index: 13
#2Eoin P. Flanagan (Mayo Clinic)H-Index: 33
Acute myelopathies are spinal cord disorders characterized by a rapidly progressive course reaching nadir within hours to a few weeks that may result in severe disability. The multitude of underlying etiologies, complexities in confirming the diagnosis, and often unforgiving nature of spinal cord damage have always represented a challenge. Moreover, certain slowly progressive myelopathies may present acutely or show abrupt worsening in specific settings and thus further complicate the diagnostic...
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#1Sophia L. Ryan (Mount Sinai Hospital)
#2Eyal Y. Kimchi (Harvard University)H-Index: 16
Delirium, sometimes referred to as encephalopathy, is an acute confusional state that is both common in hospitalized patients and associated with poor outcomes. For patients, families, and caregivers, delirium can be a traumatic experience. While delirium is one of the most common diagnoses encountered by the consulting neurologist, the majority of the time it will have been previously unrecognized as such by the care team. Neurologic syndromes such as dementia or aphasia can either be misdiagno...
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#1Pria Anand (BU: Boston University)H-Index: 12
#2Joshua P. Klein (Brigham and Women's Hospital)H-Index: 18
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#1Elizabeth Carroll (NYU: New York University)H-Index: 3
#2Ariane Lewis (NYU: New York University)H-Index: 23
Approximately 15% of deaths in developed nations are due to sudden cardiac arrest, making it the most common cause of death worldwide. Though high-quality cardiopulmonary resuscitation has improved overall survival rates, the majority of survivors remain comatose after return of spontaneous circulation secondary to hypoxic ischemic injury. Since the advent of targeted temperature management, neurologic recovery has improved substantially, but the majority of patients are left with neurologic def...
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#1Anastasia Vishnevetsky (Harvard University)H-Index: 3
#2Pria Anand (BU: Boston University)H-Index: 12
Neurologic complications are common in immunocompromised patients, including those with advanced human immunodeficiency virus, transplant recipients, and patients on immunomodulatory medications. In addition to the standard differential diagnosis, specific pathogens and other conditions unique to the immunocompromised state should be considered in the evaluation of neurologic complaints in this patient population. A thorough understanding of these considerations is critical to the inpatient neur...
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