Seminars in Arthritis and Rheumatism
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INTRODUCTION Pain is prevalent in juvenile idiopathic arthritis (JIA). Unknowns regarding the biological drivers of pain complicate therapeutic targeting. We employed neuroimaging to define pain-related neurobiological features altered in JIA. METHODS 16 male and female JIA patients (12.7 ± 2.8 years of age) on active treatment were enrolled, together with age- and sex-matched controls. Patients were assessed using physical examination, clinical questionnaires, musculoskeletal MRI, and structura...
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#1Joanna Tieu (University of Adelaide)H-Index: 2
#2Jonathan T. L. Cheah (UMMS: University of Massachusetts Medical School)
Last. Jasvinder A Singhi (UAB: University of Alabama at Birmingham)
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Abstract null null Objective null : Our primary objective was to develop an Outcome Measures in Rheumatology (OMERACT) core domain set to capture the impact of glucocorticoids (GC), both positive and negative, on patients with Rheumatic conditions. null null null Methods null : The OMERACT Filter 2.1 was used to guide core domain selection. Systematic literature reviews, qualitative studies and quantitative surveys were conducted by the OMERACT GC Impact working group to identify candidate domai...
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#1Jui-Hung Kao (NTU: National Taiwan University)
#2Ting-Yuan Lan (NTU: National Taiwan University)
Last. Song-Chou Hsieh (NTU: National Taiwan University)H-Index: 16
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ABSTRACT null null Objective null : To investigate the neonatal and maternal outcomes of patients treated with belimumab during pregnancy. null null null Materials and Methods null : We retrospectively collected patients who were treated with belimumab during pregnancy from January 2018 to October 2020 in a tertiary referral hospital in Taiwan. All patients had clinical and serological features of systemic lupus erythematosus or antiphospholipid syndrome and had been treated accordingly. The pat...
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#1C. López-Medina (UCO: University of Córdoba (Spain))H-Index: 5
#2Lourdes Ladehesa-Pineda (UCO: University of Córdoba (Spain))H-Index: 2
Last. Eduardo Collantes-Estevez (UCO: University of Córdoba (Spain))H-Index: 31
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OBJECTIVES To determine groups of factors (clusters) potentially associated with the patient global assessment (measured with the Bath Ankylosing Spondylitis Patient Global Score (BAS-G)), and to quantify the contribution of each cluster to the patient's well-being. METHODS This was a cross-sectional study in patients with a diagnosis of ankylosing spondylitis (AS) from the national, multicentre Spanish REGISPONSER-AS registry. A hierarchical cluster analysis was conducted to group the potential...
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#1Matthew C. Baker (Stanford University)H-Index: 3
#2Khushboo Sheth (Stanford University)H-Index: 3
Last. Julia F. Simard (Stanford University)H-Index: 35
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#1Tristan Pascart (Lille Catholic University)H-Index: 13
#2Paul Carpentier (Lille Catholic University)
Last. Fabio Becce (UNIL: University of Lausanne)H-Index: 21
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ABSTRACT null null Objective null To characterize peripheral vascular plaques color-coded as monosodium urate (MSU) deposition by dual-energy computed tomography (DECT) and assess their association with the overall soft-tissue MSU crystal burden. null null null Methods null Patients with suspected crystal arthropathies were prospectively included in the CRYSTALILLE inception cohort to undergo baseline knees and ankles/feet DECT scans; treatment-naive gout patients initiating treat-to-target urat...
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#1Krystel Aouad (""St. Joe's"": Saint Joseph's University)H-Index: 3
#1Krystel Aouad (""St. Joe's"": Saint Joseph's University)
Last. Laure Gossec (University of Paris)H-Index: 78
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Abstract null null Introduction null Psoriatic arthritis (PsA) is a multidimensional inflammatory disease for which multiple outcome measures can be used to assess disease activity. In 2006, the OMERACT has proposed the first core domain set in PsA. Since 2006, much work has been performed on outcome measures in PsA. null null null Objectives null The purpose of this study was to assess outcome measures collected in recent PsA registries or longitudinal cohorts. null null null Methods null A sys...
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#1Denis Poddubnyy (Charité)H-Index: 33
#2Deepak R. Jadon (University of Cambridge)H-Index: 7
Last. Dafna D. Gladman (Toronto Western Hospital)H-Index: 144
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Abstract null null Psoriatic arthritis (PsA) is a heterogenous, chronic, inflammatory musculoskeletal disease that can lead to peripheral and axial damage and loss of function. Axial involvement occurs in 25% to 70% of patients with PsA, varying greatly depending on its definition, with the key manifestations being sacroiliitis and/or spondylitis. However, there are no agreed-upon classification or diagnostic criteria for axial involvement in PsA and no consensus on treatment paradigms, which co...
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#1Marie Wetterslev (UCPH: University of Copenhagen)
#2Walter P. Maksymowych (U of A: University of Alberta)H-Index: 88
Last. A. J. Mathew (UCPH: University of Copenhagen)
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Abstract null null Objective null To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA). null null null Methods null Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises. null null null Results null In the final exercise, reliability ...
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#1Vanessa L. Kronzer (Mayo Clinic)H-Index: 6
#2Cynthia S. Crowson (Mayo Clinic)H-Index: 96
Last. Elena Myasoedova (Mayo Clinic)H-Index: 20
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Abstract null null Objective null We aimed to assess the incidence of dementia over time in patients with incident rheumatoid arthritis (RA) as compared to non-RA referents. null null null Methods null This population-based, retrospective cohort study included Olmsted County, Minnesota residents with incident RA by ACR 1987 criteria, diagnosed between 1980 and 2009. We matched non-RA referents 1:1 on age, sex, and calendar year and followed all individuals until 12/31/2019. Incident dementia was...
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Rheumatoid arthritis
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