Wiley Interdisciplinary Reviews-nanomedicine and Nanobiotechnology
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#1Peter Ludewig (UHH: University of Hamburg)H-Index: 15
#2Matthias GraeserH-Index: 12
Last. Tim Magnus (UHH: University of Hamburg)H-Index: 36
view all 11 authors...
Stroke is one of the leading worldwide causes of death and sustained disability. Rapid and accurate assessment of cerebral perfusion is essential to diagnose and successfully treat stroke patients. Magnetic particle imaging (MPI) is a new technology with the potential to overcome some limitations of established imaging modalities. It is an innovative and radiation-free imaging technique with high sensitivity, specificity, and superior temporal resolution. MPI enables imaging and diagnosis of str...
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#1Namita S. Mahadik (Indian Institute of Chemical Technology)
#2Dwaipayan Bhattacharya (BITS: Birla Institute of Technology and Science)H-Index: 5
Last. Rajkumar Banerjee (Indian Institute of Chemical Technology)H-Index: 24
view all 6 authors...
The steroid hormone receptors (SHRs) among nuclear hormone receptors (NHRs) are steroid ligand-dependent transcription factors that play important roles in the regulation of transcription of genes promoted via hormone responsive elements in our genome. Aberrant expression patterns and context-specific regulation of these receptors in cancer, have been routinely reported by multiple research groups. These gave an window of opportunity to target those receptors in the context of developing novel, ...
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#1Lauren E. Kass (UNC: University of North Carolina at Chapel Hill)
#2Juliane Nguyen (UNC: University of North Carolina at Chapel Hill)H-Index: 17
Hydrogels are a class of biomaterials widely implemented in medical applications due to their biocompatibility and biodegradability. Despite the many successes of hydrogel-based delivery systems, there remain challenges to hydrogel drug delivery such as a burst release at the time of administration, a limited ability to encapsulate certain types of drugs (i.e., hydrophobic drugs, proteins, antibodies, and nucleic acids), and poor tunability of geometry and shape for controlled drug release. This...
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#1Jianxin Wang (UW: University of Wisconsin-Madison)H-Index: 5
#2Adam J. Drelich (UW: University of Wisconsin-Madison)H-Index: 8
Last. Seungpyo HongH-Index: 37
view all 7 authors...
Viruses are infectious agents that pose significant threats to plants, animals, and humans. The current coronavirus disease 2019 pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally and resulted in over 2 million deaths and immeasurable financial losses. Rapid and sensitive virus diagnostics become crucially important in controlling the spread of a pandemic before effective treatment and vaccines are available. Gold nanoparticle (AuNP)-ba...
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#1Yunhua Guo (TJU: Tianjin University)H-Index: 1
#2Jianpu Tang (TJU: Tianjin University)H-Index: 5
Last. Dayong Yang (TJU: Tianjin University)H-Index: 26
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Deoxyribonucleic acid (DNA) has been an emerging building block to construct functional biomaterials. Due to their programmable sequences and rich responsiveness, DNA has attracted rising attention in the construction of intelligent nanomaterials with predicable nanostructure and adjustable functions, which has shown great potential in drug delivery. On the one hand, the DNA sequences with molecule recognition, responsiveness, and therapeutic efficacy can be easily integrated to the framework of...
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#1Eshant Bhatia (IITB: Indian Institute of Technology Bombay)H-Index: 3
#2Durga Kumari (IITB: Indian Institute of Technology Bombay)H-Index: 2
Last. Rinti Banerjee (IITB: Indian Institute of Technology Bombay)H-Index: 32
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Aging is a continuous process defined by a progressive functional decline in physiological parameters. Skin, being one of the most vulnerable organs, shows early signs of aging which are predominantly affected by intrinsic factors like hormone, gender, mood, enzymes, and genetic predisposition, and extrinsic factors like exposure to radiation, air pollution, and heat. Visible morphological and anatomical changes associated with skin aging occur due to underlying physiological aberrations governe...
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In recent years, more and more research enthusiasm has been devoted to the development of emerging two-dimensional (2D) monoelement materials (Xenes) and explored potential applications in various fields, especially biomedicine and bioimaging. The inspiring results attribute to their excellent physicochemical properties, including adjustable band gap, surface electronic layout characteristics, and so on, making it easier for surface modification in order to meet designated needs. As a popular in...
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Cancer immunotherapy, or the utilization of a patient's own immune system to treat cancer, has shifted the paradigm of cancer treatment. Despite meaningful responses being observed in multiple studies, currently available immunotherapy platforms have only proven effective to a small subset of patients. To address this, nanoparticles have been utilized as a novel carrier for immunotherapeutic drugs, achieving robust anti-tumor effects with increased adaptive and durable responses. Specifically, d...
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#1Guorong Jia (SC: University of Southern California)
#2Juno Van Valkenburgh (SC: University of Southern California)H-Index: 1
Last. Kai Chen (SC: University of Southern California)H-Index: 24
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Transarterial chemoembolization (TACE) is a recommended treatment for patients suffering from intermediate and advanced hepatocellular carcinoma (HCC). As compared to the conventional TACE, drug-eluting bead TACE demonstrates several advantages in terms of survival, treatment response, and adverse effects. The selection of embolic agents is critical to the success of TACE. Many studies have been performed on the modification of the structure, size, homogeneity, biocompatibility, and biodegradabi...
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#1Brinta Bhattacharjee (Jawaharlal Nehru Centre for Advanced Scientific Research)H-Index: 2
#2Sreyan Ghosh (Jawaharlal Nehru Centre for Advanced Scientific Research)H-Index: 4
Last. Jayanta Haldar (Jawaharlal Nehru Centre for Advanced Scientific Research)H-Index: 33
view all 4 authors...
Escalating medical expenses due to infectious diseases are causing huge socioeconomic pressure on mankind globally. The emergence of antibiotic resistance has further aggravated this problem. Drug-resistant pathogens are also capable of forming thick biofilms on biotic and abiotic surfaces to thrive in a harsh environment. To address these clinical problems, various strategies including antibacterial agent delivering matrices and bactericidal coatings strategies have been developed. In this revi...
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