Pharmaceutical Biology
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#1Jin-Ryul Hu (Daegu Haany University)H-Index: 1
#2Chul-Jong JungH-Index: 1
Last. Jae-Suk ChoiH-Index: 17
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CONTEXT Kyeongok-go (KOG) is a traditional mixed herb preparation consisting of Panax ginseng CA Meyer (Araliaceae), Poria cocos Wolf (Polyporaceae), Rehmannia glutinosa (Gaertner) Liboschitz ex Steudel (Orobanchaceae), and honey. Various pharmacological effects of KOG are reported, but the efficacy on respiratory diseases has not been evaluated. OBJECTIVE The anti-inflammatory, expectorant, and antitussive properties of KOG were examined using animal models of respiratory diseases. MATERIALS AN...
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Last. Zongying Tian (HUM: Hubei University of Medicine)
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Peimine and paeoniflorin can be combined for the treatment of cough in paediatrics. The interaction during the co-administration could dramatically affect the bioavailability of drugs.The interacti...
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#1Tang Donghong (Peking Union Medical College)H-Index: 1
#2Wang Chenyun (Peking Union Medical College)H-Index: 1
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The uric acid metabolism pathway is more similar in primates and humans than in rodents. However, there are no reports of using primates to establish animal models of hyperuricaemia (HUA).To establ...
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#1Luping Zhang (JLU: Jilin University)
#2Ruitao Dong (JLU: Jilin University)
Last. Zhaoli Meng (JLU: Jilin University)
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Physcion (Phy) exerts several pharmacological effects including anti-inflammatory, antioxidant, and antitumor properties.This study investigates the cytotoxicity and its underlying mechanisms of Ph...
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#1Leyu Fang (Tianjin University of Traditional Chinese Medicine)H-Index: 1
#2Lu Chen (Tianjin University of Traditional Chinese Medicine)H-Index: 6
Last. Hong Wang (Tianjin University of Traditional Chinese Medicine)H-Index: 11
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Naoxintong (NXT), a prescribed traditional Chinese medicine, widely used in cerebrovascular and cardiovascular diseases, could be effective in diabetic wounds.This study evaluates the wound healing...
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#1Lizhu Han (Shaanxi University of Chinese Medicine)H-Index: 1
#2Jing Kou (Shaanxi University of Chinese Medicine)
Last. Xiao Song (Shaanxi University of Chinese Medicine)H-Index: 3
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Re-yan-ning mixture (RYNM) is a new national drug approved by China's State Food and Drug Administration for the treatment of colds, simple pneumonia and acute bronchitis.To determine the mechanism...
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#1Danling Liang (Guangzhou University of Chinese Medicine)H-Index: 2
#2Tianqiao YongH-Index: 6
Last. Huiping HuH-Index: 3
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Poria coco F.A.Wolf (Polyporaceae) dispels dampness and promotes diuresis implying hypouricaemic action.To examine hypouricaemic action of Poria coco.Ethanol extract (PCE) was prepared by extractin...
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#1Narges Marefati (MUMS: Mashhad University of Medical Sciences)H-Index: 5
#2Vahideh Ghorani (MUMS: Mashhad University of Medical Sciences)H-Index: 6
Last. Mohammad Hosein Boskabady (MUMS: Mashhad University of Medical Sciences)H-Index: 6
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Allium cepa L. (Liliaceae), known as onion, is consumed throughout the world. Onion and its derivatives including saponins, aglycones, quercetin, cepaenes, flavonoids, organosulfurs, and phenolic c...
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#1Jiaqi LuH-Index: 2
#2Lili GuH-Index: 3
Last. Xinyue ZhangH-Index: 7
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CONTEXT Andrographolide (Andro) has a neuroprotective effect and a potential for treating Alzheimer's disease (AD), but the mechanism has not been elucidated. OBJECTIVE The efficacy of Andro on p62-mediated Kelch-like ECH-associated protein 1(Keap1)-Nuclear factor E2 related factor 2 (Nrf2) pathways in the aluminium maltolate (Al(mal)3)-induced neurotoxicity in PC12 cell was explored. MATERIALS AND METHODS PC12 cells were induced by Al(mal)3 (700 μM) to establish a neurotoxicity model. Following...
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#1Shujun Wei (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 4
#2Qing Zhang (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 5
Last. Yongxiang Gao (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 5
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Guizhi-Shaoyao-Zhimu decoction (GSZD) is commonly used to treat rheumatoid arthritis (RA), but its mechanism is unclear.To investigate the effect of GSZD on bone erosion in type II collagen (CII)-i...
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