Papers 3,810
1 page of 381 pages (3,810 results)
#1Qian Liu (CQUPT: Chongqing University of Posts and Telecommunications)
Last. Hao Liu (NSMC: North Sichuan Medical University)H-Index: 1
view all 11 authors...
Intestinal inflammation is a common disease which can further lead to inflammatory bowel disease and even intestinal cancer. The increasing focus has come to the role of short-chain fatty acid (SCFA) in various bowel diseases. Hence, this study was designed to explore the specific role of SCFA in intestinal inflammation. In vivo and in vitro models of intestinal inflammation were constructed by lipopolysaccharide (LPS) injection in mice and LPS treatment on intestinal epithelial cells. A possibl...
#1Liu Yuhan (HUST: Huazhong University of Science and Technology)H-Index: 1
#2Luorui Shang (HUST: Huazhong University of Science and Technology)H-Index: 1
Last. Shenglan Yang (HUST: Huazhong University of Science and Technology)H-Index: 1
view all 6 authors...
Emodin, the effective component of the traditional Chinese medicine Dahuang, has anti-inflammatory effects. However, the protective effects and potential mechanisms of emodin are not clear. This study investigated the protective effects and potential mechanisms of emodin on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vitro and in vivo. In vivo, we designed an LPS-induced ALI rat model. In vitro, we chose the J774A.1 cell line to establish an inflammatory cellular model, and knock...
#1Monu (CBT: Institute of Genomics and Integrative Biology)H-Index: 1
#2Prachi Agnihotri (CBT: Institute of Genomics and Integrative Biology)H-Index: 1
Last. Sagarika Biswas (CBT: Institute of Genomics and Integrative Biology)H-Index: 9
view all 3 authors...
Rheumatoid arthritis (RA) is a chronic inflammatory, autoimmune disease that gradually affects the synovial membrane and joints. Many intrinsic and/or extrinsic factors are crucial in making RA pathology challenging throughout the disease. Substantial enzymatic or non-enzymatic modification of proteins driving inflammation has gained a lot of interest in recent years. Endogenously modified glycated protein influences disease development linked with AGEs/non-AGEs and is reported as a disease mark...
#1Zhao Chen (XJTU: Xi'an Jiaotong University)H-Index: 6
#2Lifang Tian (XJTU: Xi'an Jiaotong University)H-Index: 12
Last. Rongguo Fu (XJTU: Xi'an Jiaotong University)H-Index: 9
view all 7 authors...
Hyperglycemia-induced oxidative stress in podocytes exerts a major role in the pathological process of diabetic nephropathy. Tripartite motif-containing protein 32 (TRIM32) has been reported to be a key protein in the modulation of cellular apoptosis and oxidative stress under various pathological processes. However, whether TRIM32 participates in the regulation of high glucose (HG)-induced injury in podocytes has not been investigated. This work aimed to assess the possible role of TRIM32 in me...
#1Chun Wang (Tongji University)
#2Jingshu Yang (Fudan University)
Last. Changsheng Du (Tongji University)H-Index: 11
view all 11 authors...
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), characterized by demyelinating neuropathy. The etiology of MS is not yet clear and its treatment remains a major medical challenge. While we search for drugs that can effectively treat experimental autoimmune encephalomyelitis (EAE), the animal model of MS, we also hope to further explore its possible pathogenesis. In the present study, we investigated whether methyl butyrate (MB) could alleviate EAE and its po...
#1Fang Cao (ZMU: Zunyi Medical University)
Last. Hua Zhong (WHU: Wuhan University)H-Index: 6
view all 6 authors...
#1Tuan-Mao GuoH-Index: 2
#2Yan-Li XingH-Index: 2
Last. Jiang Xu
view all 7 authors...
Rheumatoid arthritis (RA) is chronic inflammatory autoimmune disease. The crucial role of long non-coding RNA (lncRNA) in the progression of RA has been highlighted. Hence, this study was designed to explore the specific downstream mechanism of lncRNA nuclear-enriched abundant transcript 1 (NEAT1) in RA. Initially, the expression of NEAT1, p-p65, p300, and IL-18 in clinical tissues and cells was determined. Then, interactions among p65, NEAT1, p300, CBP, and IL-18 were investigated by immunofluo...
#1Youwen Mei (CQMU: Chongqing Medical University)
#2yuxin Ran (CQMU: Chongqing Medical University)H-Index: 1
Last. Hongbo Qi (CQMU: Chongqing Medical University)H-Index: 21
view all 7 authors...
This study aimed to investigate whether interleukin-27 (IL-27) activates maternal peripheral blood mononuclear cells (PBMCs) and induces inflammatory responses in amniotic epithelial cells in preterm labour (PL). The expression of IL-27p28, EBI3 and IL-27Rα was compared in maternal PBMCs of the PL, term labour (TL) and term not in labour (TNL) groups. The relationship between IL-27 and molecules associated with PBMC activation was investigated using bioinformatic and quantitative reverse transcr...
#1Cheng Hu (NJUCM: Nanjing University of Chinese Medicine)H-Index: 5
#2Meng-Lin He (NJUCM: Nanjing University of Chinese Medicine)
Last. Weiqian Tian (NJUCM: Nanjing University of Chinese Medicine)H-Index: 1
view all 8 authors...
Neuropathic pain (NP) treatment remains a challenge because the pathomechanism is not yet fully understood. Because of low treatment efficacy, there is an important unmet need in neuropathic pain patients, and the development of a more effective pharmacotherapy is urgently required. Neuroinflammation induced by oxidative stress-mediated activation of nuclear factor-kappa B (NF-κB) plays an important role in NP. In this study, we aimed to investigate the protective properties of tetrahydropalmati...
#1Siyuan Huang (SDU: Shandong University)H-Index: 1
#2Rong Zeng (SDU: Shandong University)
Last. Liang Dong (SDU: Shandong University)H-Index: 17
view all 8 authors...
Asthma is a chronic disease closely related to airway inflammation. It has been proven that type 2 innate lymphoid cells (ILC2s) play an essential role in airway inflammation in asthma. Furthermore, there is growing evidence that Follistatin-like 1 (FSTL1) can participate in various inflammatory reactions mediated by the JAK/STAT signaling pathway, among others. Therefore, we put forward a new hypothesis: FSTL1 promotes asthmatic airway inflammation by activating ILC2. This study generated an ov...
Top fields of study
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.