Transplant International
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#1Julia M. Grottenthaler (University of Tübingen)H-Index: 2
#2Judith K Füger (University of Tübingen)
Last. Martina Guthoff (University of Tübingen)H-Index: 17
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Posttransplantation diabetes mellitus (PTDM) is a relevant complication following liver transplantation with profound impact on morbidity and mortality. To date, little is known about the evolution and dynamics of glucose metabolism and the impact of prediabetes in long-term follow-up. To address this issue, all consecutive adult liver transplant recipients (n=429) from a European university hospital transplant center between 2007 and 2017 were analyzed retrospectively. In patients without pre-e...
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#1Maarten Coemans (Katholieke Universiteit Leuven)H-Index: 8
#2Aleksandar Senev (Katholieke Universiteit Leuven)H-Index: 7
Last. Maarten Naesens (Katholieke Universiteit Leuven)H-Index: 55
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The interplay between donor-specific anti-HLA antibodies (HLA-DSA), histology of active antibody-mediated rejection (aABMRh ), transplant glomerulopathy (cg) and graft failure in kidney transplantation remains insufficiently understood. We performed a single-center cohort study (n=1000) including 2761 protocol and 833 indication biopsies. Patients with pre-transplant HLA-DSA were more prone to develop aABMRh (OR 22.7, 95% CI, 11.8 - 43.7, p<0.001), cg (OR 5.76, 95% CI, 1.67 - 19.8, p=0.006) and ...
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#1Babak J. Orandi (UAB: University of Alabama at Birmingham)H-Index: 23
#2Sanjay Kulkarni (Yale University)H-Index: 21
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#1Piyavadee Homkrailas (UCLA: University of California, Los Angeles)H-Index: 1
#2Suphamai Bunnapradist (UCLA: University of California, Los Angeles)H-Index: 62
White kidney transplant candidates have the highest pre-transplant mortality rate compared to other ethnicities. The reason for a higher mortality rate is not well understood. Estimated post transplant survival (EPTS) score has been used to predict patient survival after transplant and may be associated with pre-transplant survival. First-time kidney transplant candidates listed between 2015-2018 were identified from the OPTN database. Individuals listed for multiple organs, at multiple centers,...
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#1John M. O’Callaghan (University of Oxford)H-Index: 9
#2Liset H. M. Pengel (University of Oxford)H-Index: 12
To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch. The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. This page of Transplant International offers commentaries on methodological issues and clinical implications on two articles of particular interest from the CET Transplant ...
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#1Thijmen Visseren (EUR: Erasmus University Rotterdam)H-Index: 2
#2Nicole S. Erler (EUR: Erasmus University Rotterdam)H-Index: 16
Last. Sarwa Darwish Murad (EUR: Erasmus University Rotterdam)H-Index: 32
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BACKGROUND Liver transplantation for primary sclerosing cholangitis (PSC) can be complicated by recurrence of PSC (rPSC). This may compromise graft survival but the effect on patient survival is less clear. We investigated the effect of post-transplant rPSC on graft and patient survival in a large European cohort. METHODS Registry data from the European Liver Transplant Registry regarding all first transplants for PSC between 1980 and 2015 were supplemented with detailed data on rPSC from 48 out...
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#1Ane M. Andres (Hospital Universitario La Paz)H-Index: 11
#2Paloma TalayeroH-Index: 8
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Aim null To review our experience using sirolimus in a single center pediatric intestinal transplantation cohort. null Patient/methods null Intestinal transplant patients with more than 3 months follow-up were divided in two groups according to their immunosuppression regimen: tacrolimus, (TAC group, n=45 grafts) or sirolimus (SRL group, n=38 grafts), which included those partially or completely converted from tacrolimus to sirolimus. The indications to switch were tacrolimus side-effects and im...
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#1Marieta Theodorakopoulou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 3
#2Afroditi K. BoutouH-Index: 11
Last. Pantelis A. Sarafidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 48
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Patients with kidney failure often present with reduced cardiovascular functional reserve and exercise tolerance. Previous studies on cardiorespiratory fitness examined with cardiopulmonary-exercise-testing (CPET) in kidney-transplant-recipients (KTR) had variable results. This is a systematic review and meta-analysis of studies examining cardiovascular functional reserve with CPET in KTR in comparison to patients with kidney failure (CKD-Stage-5 before dialysis, hemodialysis or peritoneal dialy...
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#1Abbas Al-Kurd (HFH: Henry Ford Hospital)
#2Toshihiro Kitajima (HFH: Henry Ford Hospital)H-Index: 8
Last. Marwan S Abouljoud (HFH: Henry Ford Hospital)H-Index: 24
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While adverse effects of prolonged recipient warm ischemia time (rWIT) in liver transplantation (LT) have been well investigated, few studies have focused on possible positive prognostic effects of short rWIT. We aim to investigate if shortening rWIT can further improve outcomes in donation after brain-death liver transplant (DBD-LT). Primary DBD-LT between 2000 and 2019 were retrospectively reviewed. Patients were divided according to rWIT (≤30, 31-40, 41-50, and >50 min). The requirement of in...
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#1Johannes KlägerH-Index: 3
#2Farsad EskandaryH-Index: 22
Last. Heinz RegeleH-Index: 50
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Background Gene expression profiling of renal allograft biopsies revealed the Duffy antigen receptor for chemokines (DARC) as being strikingly upregulated in antibody-mediated rejection (ABMR). DARC has previously been shown to be associated with endothelial injury. This study aimed at assessing the value of DARC immunohistochemistry as diagnostic marker in ABMR. Methods The study was performed on 82 prospectively collected biopsies of a clinically well-defined population (BORTEJECT trial, NCT01...
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Top fields of study
Surgery
Immunology
Liver transplantation
Kidney transplantation
Transplantation
Diabetes mellitus
Medicine