Chinese Journal of Natural Medicines
Papers 3191
1 page of 320 pages (3,191 results)
#1Hai-Zhen Liang (PKU: Peking University)
Last. Yong Jiang (PKU: Peking University)H-Index: 31
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There are two source plants for the traditional Chinese medicine Murrayae Folium et Cacumen (MFC) in the Chinese Pharmacopoeia, i.e. Murraya exotica L. and M. paniculata (L.) Jack. Herein, a chemical comparison of M. exotica and M. paniculata by high performance liquid chromatography (HPLC) fingerprint analysis coupled with chemometrics and network pharmacology was performed. The main peaks in the fingerprints were identified by liquid chromatography coupled with ion trap/time-of-flight mass spe...
#1Ye Zhong (SPU: Shenyang Pharmaceutical University)
#2Nan Liang (SPU: Shenyang Pharmaceutical University)
Last. Maosheng Cheng (SPU: Shenyang Pharmaceutical University)H-Index: 21
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Natural products are one of the important sources for the discovery of new drugs. Betulinic acid (BA), a pentacyclic triterpenoid widely found in various plant sources, exhibits powerful biological effects, including antitumor activity against various types of cancer cells. Numerous BA derivatives have been designed and prepared to overcome its disadvantages, including poor water solubility and low bioavailability. This review summarizes the current status of the structural diversity of BA deriv...
Buxrugulosides A–E, four lignan glycosides ( null 1–4 null ) and a protocatechuate derivative ( null 5 null ) featuring a rare (N, N-diethyl)methyl amino group at aromatic rings, were obtained from the aerial parts of Buxus rugulosa, which is famous for treating coronary heart disease. Their structures including absolute configurations were elucidated by HRMS, 1D and 2D NMR, and by comparing their CD data with previous reports. Compound null null 1 null null was a rare sesquilignan, and all of t...
This work aims to establish a quality control method and evaluate the effects in glucose and lipids for fruit body of Isaria cicadae Miquel from strain Ic-17-7(Ic-17-7fb) in type 2 diabetes (T2DM) rat model. Random amplified polymorphic DNA, sequence-characterized amplified region, and high-performance liquid chromatography (HPLC) were used for the quality control of Ic-17-7fb. The pharmacological effects on streptozocin (STZ)-induced high-fat diet-fed Albino Wistar rats, divided into model, met...
Simiao Wan (SMW) is a traditional Chinese formula, including Atractylodis Rhizoma, Achyranthis Bidentatae Radix, Phellodendri Chinensis Cortex and Coicis Semen at the ratio of 1:1:2:2. It could be used to the treatment of diabetes. However, its bioactive compounds and underlying mechanism are unclear. This study aimed to screen the antilipolytic fraction from SMW and investigate its therapeutic mechanisms on hepatic insulin resistant. Different fractions of SMW were prepared by membrane separati...
Four new prenylflavonoid glycosides, namely koreanoside H-K ( 1 - 4 ), together with eleven known ones ( 5 – 15 ) were isolated from the leaves of Epimedium koreanum Nakai. Their structures were elucidated by spectroscopic techniques including 1D NMR, 2D NMR, HRESIMS, IR and UV. The identification of the sugar moieties was carried out by means of acid hydrolysis and HPLC analysis of their derivatives. It is worth noting that compound null 3 null and compound null 4 null were elucidated to contai...
#1Zou Jian (JNU: Jinan University)
#2Zhang Shuai (SPU: Shenyang Pharmaceutical University)
Last. Gao Hao (SPU: Shenyang Pharmaceutical University)
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Biotransformation of α-asarone by Alternaria longipes CGMCC 3.2875 yielded two pairs of new neolignans, (+) (7S, 8S, 7′S, 8′R) iso-magnosalicin ( null 1a null )/(−) (7R, 8R, 7'R, 8′S) iso-magnosalicin ( null 1b null ) and (+) (7R, 8R, 7′S, 8'R) magnosalicin ( null 2a null )/(−) (7S, 8S, 7′R, 8'S) magnosalicin ( null 2b null ), and four known metabolites, (±) acoraminol A ( null 3 null ), (±) acoraminol B ( null 4 null ), asaraldehyde ( null 5 null ), and 2, 4, 5-trimethoxybenzoic acid ( null 6 n...
#1Jinjin Zhang (CAS: Chinese Academy of Sciences)H-Index: 6
#2Baosong Chen (CAS: Chinese Academy of Sciences)H-Index: 6
Last. Hongwei Liu (CAS: Chinese Academy of Sciences)H-Index: 62
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A chemical investigation on the fermentation products of Sanghuangporus sanghuang led to the isolation and identification of fourteen secondary metabolites ( null 1 null − null 14 null ) including eight sesquiterpenoids ( null 1 null − null 8 null ) and six polyphenols ( null 9 null − null 14 null ). Compounds null null 1 null − null 3 null null were sesquiterpenes with new structures which were elucidated based on NMR spectroscopy, high resolution mass spectrometry (HRMS) and electronic circula...
#1Fang-Shen Liu (SPU: Shenyang Pharmaceutical University)
#2Ting-Ting Zhang (SPU: Shenyang Pharmaceutical University)
Last. Zhong Yuan (SPU: Shenyang Pharmaceutical University)
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Six unprecedented tirucallane-type triterpenoids ( null 1 null − null 6 null ), co-occurring with ten known related triterpenoids, were isolated from methylene chloride extract of the resin of Boswellia carterii Birdw. By the application of the comprehensive spectroscopic data, the structures of the compounds were clarified. The experimental electronic circular dichroism spectra were compared with those calculated, which allowed us to unambiguously assign the absolute configurations. Compounds n...
Ocotillol (OT)-type ginsenosides, one subtype of ginsenosides, consist of a dammarane skeleton and a tetrahydrofuran ring. Most naturally-occurring OT-type ginsenosides exist in Panax species, particularly in Panax quinquefolius, which may be attributed to the warm and humid climate of its native areas. Till now, merely 28 types of naturally-occurring OT-type ginsenosides have been isolated. In contrast, semi-synthesized OT-type ginsenosides are attracted considerable attentions. These ginsenosi...
Top fields of study
Organic chemistry
Traditional medicine