Biomedical Materials
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#1Deboki Naskar (IIT-KGP: Indian Institute of Technology Kharagpur)H-Index: 18
#2Sunaina Sapru (IIT-KGP: Indian Institute of Technology Kharagpur)H-Index: 7
Last. Subhas C. Kundu (IIT-KGP: Indian Institute of Technology Kharagpur)H-Index: 64
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The emerging field of tissue engineering and regenerative medicines utilizing artificial polymers is facing many problems. Despite having mechanical stability, non-toxicity, and biodegradability, most of them lack cytocompatibility and biocompatibility. Natural polymers (such as collagen, hyaluronic acid, and others), including blends, are introduced to the field to solve some of the relevant issues. Another natural biopolymer: silkworm silk gained special attention primarily due to its specific...
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#1Mohammad Ranjbar Hamghavandi (University of Gilan)
#2Arash Montazeri (University of Gilan)H-Index: 3
Last. Malihe PishvaeiH-Index: 2
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Mg and its alloys are biodegradable and mechanically strong materials, which can be used for an orthopedic implant and device applications, but corrosion rate of these alloys is high. In this research, the nanocomposite coatings of chitosan (CS)/graphene oxide (GO) were fabricated to improve the corrosion resistance of the Mg-2 wt% Zn scaffold. The contents of the GO nanosheets and the pulse electrodeposition process parameters, including peak current density (CD) and duty cycle (DC), will also ...
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#1Isnayra Kerolaynne Carneiro Pacheco (Federal University of Piauí)
#2Fernando da Silva Reis (Federal University of Piauí)H-Index: 1
Last. Ana Cristina Vasconcelos Fialho (Federal University of Piauí)H-Index: 1
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The development of "smart" scaffolds has achieved notoriety among current prospects for bone repair, especially for chronic osteopathies, such as osteoporosis. Millions of individuals in the world suffer from poor bone healing due to osteoporosis. The objective of this work was to produce and characterize castor polyurethane scaffolds (Ricinus communis L.), as well as to evaluate its in vitro biocompatibility with stem cells and osteoinductive effect in vivo on bone failures in a leporid model o...
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#1Jing-Zhu Duan (PRC: China Medical University (PRC))H-Index: 1
Last. Yang Yang (PRC: China Medical University (PRC))H-Index: 3
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Ti-Si-xCu coatings (TS-xC,x= 5, 10 and 15 wt.%) with advanced bio-corrosion resistance, excellent antibacterial property and biocompatibility were laser cladded on Ti-6Al-4V (TAV) substrate which is widely used as endosseous implants. The bio-corrosion resistance of the TAV substrate was improved due to the presence of Ti5Si3and TiCu phases in the coatings. The addition of Cu in the precursor contributes to the improvement of the antibacterial property of TAV substrate. Meanwhile, induced normal...
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#1Xing Huang (SHU: Shanghai University)H-Index: 2
#2Jiaxin Zhang (SHU: Shanghai University)H-Index: 1
Last. Bing Wang (CAS: Chinese Academy of Sciences)H-Index: 35
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Background null Hydroxycamptothecin (HCPT) is a topoisomerase I inhibitor, and it has been widely used clinically in the treatment of primary liver cancer, gastric cancer, and other tumors. The clinical application of HCPT is limited by its water solubility, and it has certain toxicity to patients with tumor. Therefore, the effective tumor site accumulation of HCPT is necessary. null Methods null This work studied the inhibitory effect of HCPT on the proliferation and migration of human liver ca...
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#1Lucas R.X. Cortella (USP: University of São Paulo)H-Index: 2
#2Idágene A. Cestari (USP: University of São Paulo)H-Index: 11
Last. Ismar N. CestariH-Index: 6
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Surface functionalization of polymers aims to introduce novel properties that favor bioactive responses. We have investigated the possibility of surface functionalization of polyethylene terephthalate (PET) sheets by the combination of laser ablation with hot embossing and the application of such techniques in the field of stem cell research. We investigated the response of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to topography in the low micrometer range. HiPSC-CMs...
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#1Yuting Huang (Hunan University)H-Index: 1
#2Zheng Zhou (Hunan University)H-Index: 5
Last. Hairong Liu (Hunan University)H-Index: 13
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3D bioprinting technology displays many advantages for tissue engineering applications, but its utilization is limited by veryfew bioinks available for biofabrication. In this study, a novel type of bioink, which includes three methacryloyl modifiedmannans, was introduced to 3D bioprinting for tissue engineering applications. Yeast mannan (YM) was modified by reactingwith methacrylate anhydride (MA) at different concentrations, and three YM derived bioinks were obtained, which weretermed as YM-M...
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#1Ching-Chien Chiang (Memorial Hospital of South Bend)
#2Ming-Kai Hsieh (Memorial Hospital of South Bend)H-Index: 1
Last. Po-Liang Lai (Memorial Hospital of South Bend)H-Index: 25
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Poly(methyl methacrylate) (PMMA) has been widely used in orthopedic applications, but bone ingrowth and toxic monomer release are drawback of this material. Particle reinforcement with osteoconductive substitute, such as calcium sulfate (CaSO4), is one of the solutions used to modify PMMA bone cement. The current study investigated the mechanical, chemical and biological properties of CaSO4-augmented bone cement. Mechanical strength was measured by a material testing machine. The concentration o...
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#1Stefanie Heltmann-Meyer (FAU: University of Erlangen-Nuremberg)
#2Dominik Steiner (FAU: University of Erlangen-Nuremberg)H-Index: 7
Last. Raymund E. Horch (FAU: University of Erlangen-Nuremberg)H-Index: 59
view all 9 authors...
In situtissue engineering is an emerging field aiming at the generation of ready-to-use three-dimensional tissues. One solution to supply a proper vascularization of larger tissues to provide oxygen and nutrients is the arteriovenous loop (AVL) model. However, for this model, suitable scaffold materials are needed that are biocompatible/non-immunogenic, slowly degradable, and allow vascularization. Here, we investigate the suitability of the known gelatin methacryloyl (GelMA)-based hydrogel fori...
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#1Şükrü Öztürk (Hacettepe University)H-Index: 3
#1Sukru Ozturk (Hacettepe University)H-Index: 3
Last. Kezban Ulubayram (Hacettepe University)H-Index: 19
view all 8 authors...
In this study, we evaluated cardiomyogenic differentiation of electromechanically stimulated rat bone marrow-derived stem cells (rt-BMSCs) on an acellular bovine pericardium (aBP) and we looked at the functioning of this engineered patch in a rat myocardial infarct (MI) model. aBP was prepared using a detergent-based decellularization procedure followed by rt-BMSCs seeding, and electrical, mechanical, or electromechanical stimulations (3 millisecond pulses of 5 V cm-1at 1 Hz, 5% stretching) to e...
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Biomedical engineering
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Organic chemistry
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Biocompatibility
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